Changeflow GovPing

Latest changes

US DARPA News
Favicon for www.darpa.mil

DARPA Launches HARQ for Heterogeneous Quantum Computing

DARPA announced the launch of the Heterogeneous Architectures for Quantum (HARQ) program on April 14, 2026, an effort to overcome barriers in quantum computing by moving beyond single-technology qubit systems to achieve scalable, practical applications. Nineteen performer teams from 15 organizations will work on two parallel workstreams over 24 months: MOSAIC (software frameworks and circuit compilers) and QSB (hardware interconnects for qubit communication). The program aims to establish heterogeneous quantum computing architectures that combine different qubit types.

Routine Notice Defense & National Security
US DARPA News
Favicon for www.darpa.mil

DARPA ALIAS Autonomous Black Hawk Delivered to U.S. Army

DARPA has delivered an experimental fly-by-wire H-60Mx Black Hawk helicopter equipped with the Sikorsky MATRIX autonomy suite to the U.S. Army for advanced operational testing. This delivery marks the completion of DARPA's Aircrew Labor In-Cockpit Automation System (ALIAS) program, which achieved the world's first uninhabited Black Hawk flight in 2022. Under the technology transition agreement between DARPA and the Army's Project Manager for Utility Helicopters, the Army Combat Capabilities Development Command will use the helicopter as a flying laboratory to mature reduced-crew and fully autonomous flight capabilities.

Routine Notice Defense & National Security
Germany LBA News
Favicon for www.lba.de

Ground Handling Declaration Deadline 27 March 2027

The German Federal Aviation Authority (LBA) is notifying ground handling service providers of their mandatory declaration obligation under Article 2 of Regulation (EU) 2025/20, falling within the scope of Regulation (EU) 2018/1139. The LBA, designated by the Federal Ministry for Digital and Transport (BMV) for supervision under Article 3 of Regulation (EU) 2020/23, requests timely submission of declarations using the ORGH.DEC.100 Annex I form. The compliance deadline is 27 March 2027, after which affected ground handling services must submit declarations to the competent authority in the member state where their main business seat is located.

Routine Notice Aviation
Germany LBA News
Favicon for www.lba.de

LBA Informs Passengers of EU Rights During Middle East Flight Disruptions

The German Federal Aviation Authority (LBA) published passenger rights guidance on 02.03.2026 in response to widespread flight disruptions caused by the Middle East security situation. The notice explains applicability of EU Regulation 261/2004, covering care obligations, rerouting/refund options, and distance-based compensation, while clarifying that extraordinary circumstances may exempt airlines from compensation payments. The LBA provides practical recommendations for affected travelers, including contact procedures for airlines and tour operators.

Routine Notice Aviation
Germany LBA News
Favicon for www.lba.de

German Airports Prepare for Entry-Exit System Wait Times

Germany's Luftfahrt-Bundesamt (LBA) announced that the EU-wide Entry-Exit System (EES) for electronic recording of third-country nationals entering the Schengen area will be fully operational at German airports beginning 1 April 2026. The system, rolled out since 12 October 2025, replaces traditional passport stamps with digital biometric registration (fingerprints and facial images). Travelers are advised to expect potential wait times during peak travel periods and to plan additional time for border control procedures.

Routine Notice Immigration
Favicon for cnpd.public.lu

Training Session on Data Protection Basics, 15th Jun

CNPD Luxembourg published an announcement for a data protection basics training session scheduled for 15 June 2026. The English-language version of the page contains no substantive content and redirects users to the French-language version of the same page. No compliance obligations, registration details, or further information are provided in the available content.

Routine Notice Data Privacy
Favicon for cnpd.public.lu

CNPD Wins Court Judgment Against Amazon for GDPR Violations

The Luxembourg Administrative Court on March 12, 2026 endorsed the CNPD's 2021 compliance order against Amazon Europe Core S.à r.l. for GDPR violations related to online behavioural advertising, confirming that Amazon's reliance on legitimate interests as a legal basis was not justified. The court also upheld the CNPD's finding that Amazon's information procedures did not comply with GDPR at the time of the decision. Amazon had already complied with the compliance order prior to the hearing. However, the court annulled the financial penalty, citing post-decision CJEU case law requiring a different analytical framework for assessing whether Amazon demonstrated negligence.

Priority review Enforcement Data Privacy
EASA News
Favicon for www.easa.europa.eu

EASA Publishes Revision 24 of Easy Access Rules for Air Operations

EASA published Revision 24 from March 2026 of the Easy Access Rules for Air Operations (EAR for Air OPS), now available as an enhanced online publication alongside PDF and machine-readable XML formats. The revision incorporates Commission Implementing Regulation (EU) 2025/2293 correcting Regulation (EU) No 965/2012, EASA Executive Director Decision 2025/020/R amending AMC and GM to Part-ORO and Part-SPA on management systems, ATQP, and FDM programmes, and EASA Executive Director Decision 2025/023/R amending AMC and GM to Part-Definitions and Part-NCO on gyroplane flight crew licensing and non-commercial VFR operations. The enhanced online publication offers optimised performance, permalinks to the latest rule versions, and improved search and navigation across devices.

Routine Notice Aviation
EASA News
Favicon for www.easa.europa.eu

Three EASA Roles: Structures Expert, Senior Military Advisor, Certification Expert, Deadline April 30

EASA published three new vacancy notices on its Careers portal: Structures Expert, Senior Military Advisor to the Executive Director, and Certification Expert for Hydromechanical and Flight Control Systems. All three positions share the same application deadline of April 30, 2026 at 23:59 CET, with candidates required to apply through the EASA Careers portal at careers.easa.europa.eu.

Routine Notice Aviation
EASA News
Favicon for www.easa.europa.eu

EASA and EUROCONTROL Publish Joint Action Plan for GNSS Safety

EASA and EUROCONTROL jointly published an Action Plan on March 26, 2026 to strengthen the safety and resilience of European aviation operations against Global Navigation Satellite System (GNSS) interference, which poses an increasing threat particularly near conflict zones. The Plan sets out short, mid, and longer-term measures including joint monitoring, data-sharing, harmonised operational procedures, updated guidance for flight crews and air traffic controllers, and collaboration with aircraft manufacturers and the avionics industry to develop more interference-resilient solutions. The Action Plan addresses concerns raised in a June 6, 2025 letter from 13 EU Member States calling for coordinated European action on Radio Frequency Interference events affecting GNSS-based systems.

Priority review Notice Aviation
Hungary NAIH News
Favicon for www.naih.hu

NAIH Warns Public Bodies About Lawful Document Destruction Requirements

Hungary's NAIH issued a public notice on April 17, 2026, warning all public bodies that destruction of public interest data must comply with statutory procedures, including proper authorization, archival approval, and documentation. The authority explicitly references Section 220 of the Criminal Code, stating that unauthorized destruction may constitute the criminal offense of 'Abuse of Public Interest Data,' and that obstructing access to public interest data may also trigger disciplinary or labor law liability.

Priority review Notice Data Privacy
Hungary NAIH News
Favicon for www.naih.hu

EU Parliament Rejects Chat Control 1.0 Extension

The European Parliament voted 228 in favor, 311 against, and 92 abstentions on March 26, 2026, to reject the European Commission's proposal to extend the temporary exemption under Regulation (EU) 2021/1232 (Chat Control 1.0). As a result, the legal framework permitting providers of interpersonal communications services—webmail, messaging, and VoIP—to voluntarily detect, report, and remove CSAM in private communications ceased to apply starting April 4, 2026. Negotiations on the permanent framework (Chat Control 2.0 / CSAR) continue, with the next trilogue expected in April 2026.

Priority review Notice Data Privacy
Hungary NAIH News
Favicon for www.naih.hu

Gyerekeknek szóló adatvédelmi rajzpályázat a NAIH-tól

A NAIH adatvédelmi témájú gyermekrajz-pályázatot hirdet általános iskolás tanulók számára, beküldési határidő: 2026. május 20. A pályamunkákat zárt borítékban kell benyújtani.

Routine Notice Data Privacy
Italy MAECI
Favicon for www.esteri.it

Italy–Poland Strategic Forum: Tajani and Sikorski Sign Cooperation Agreement

Italian Foreign Minister Antonio Tajani and Polish Foreign Minister Radosław Sikorski convened the Italy–Poland Strategic Forum in Rome on April 22, 2026, signing an agreement to strengthen political and diplomatic dialogue and strategic cooperation on foreign policy within the EU, UN, and NATO frameworks, while reaffirming shared support for Ukraine. The forum brought together over 150 participants from institutions, academia, think tanks, and business, discussing energy security, migration, countering disinformation, Western Balkans, and Africa. Bilateral trade reached EUR 37 billion in 2025, with Italian exports rising 5.9%.

Routine Notice International Trade
Italy MAECI
Favicon for www.esteri.it

Tajani and Tripodi Attend EU Foreign Affairs Council in Luxembourg

Italian Foreign Minister Antonio Tajani and Undersecretary Maria Tripodi attended the EU Foreign Affairs Council meeting in Luxembourg on April 21, 2026. The 27 EU Member States discussed the twentieth sanctions package against Russia, Ukraine reconstruction support, hybrid threat measures targeting Moldova, a Middle East ceasefire between Israel and Lebanon, and preparations for EU-Syria and EU-Armenia high-level dialogues. Italy reaffirmed commitments to freedom of navigation in the Strait of Hormuz and support for Lebanese government reforms as the UNIFIL mission approaches conclusion.

Routine Notice Sanctions
Italy MAECI
Favicon for www.esteri.it

EU Statement Marks Third Anniversary of Sudan Conflict

The EU High Representative, on behalf of the European Union, issued a statement on April 21, 2026 marking three years since the outbreak of war in Sudan between the Sudanese Armed Forces (SAF) and the Rapid Support Forces (RSF). The statement reaffirms EU commitment to Sudan's unity, sovereignty and territorial integrity, renews calls for an immediate and lasting ceasefire, demands safe humanitarian access, and supports accountability for grave violations of international humanitarian law and human rights law. At the Sudan Conference in Berlin on April 15, 2026, international donors pledged €1.5 billion in aid, including €812 million from the EU and its Member States. The EU indicated it will examine additional sanctions aimed at the war economy.

Routine Notice International Trade
Favicon for www.fincen.gov

Index of US FinCEN Advisories on Financial Crime

FinCEN published an index page listing all its financial crime advisories from 2020 to 2026. The index covers 20 advisories addressing topics including health care fraud, transnational money laundering networks, Iranian illicit oil smuggling, ISIS financing, fentanyl precursor chemicals, ransomware, elder financial exploitation, kleptocracy, COVID-19 fraud, and human trafficking. The page provides direct links to individual advisory documents.

Routine Notice Anti-Money Laundering
US EIA News
Favicon for www.eia.gov

EIA Launches Voluntary Pilot Surveys on Data Center Energy Use

EIA has launched three voluntary pilot field studies to assess energy consumption in data centers across Texas, Washington state, and the Northern Virginia-DC region. The agency identified 196 companies operating data centers in these targeted areas and will ask each company to report on at least one data center's energy sources, electricity consumption, site characteristics, server metrics, and cooling systems. Participation in the web-based surveys and in-person interviews is voluntary, with Administrator Tristan Abbey noting the effort aims to modernize data collection toward faster cycles and finer detail.

Routine Notice Energy
US EIA News
Favicon for www.eia.gov

Annual Energy Outlook 2026 Explores U.S. Energy Futures Through 2050

The U.S. Energy Information Administration (EIA) released the Annual Energy Outlook 2026 (AEO2026), projecting U.S. energy futures through 2050 across 11 alternative scenarios. Key findings show national electricity demand has risen 2.1% annually over the past five years and is projected to grow at an average annual rate of 0.9%–1.6% per year through 2050, driven primarily by data center load. Natural gas production is projected to grow from 107 Bcf/d in 2025 to between 133 Bcf/d and 151 Bcf/d by 2050, while U.S. crude oil production remains relatively stable at 12.4–12.7 million b/d by 2050 compared with 13.6 million b/d in 2025.

Routine Notice Energy
US EIA News
Favicon for www.eia.gov

EIA April STEO: Hormuz Closure Drives Oil Shut-Ins to 9.1M b/d, Brent to Peak $115/b

The EIA's April Short-Term Energy Outlook forecasts that the closure of the Strait of Hormuz will force collective shut-ins of 9.1 million barrels per day (b/d) in April 2026 across Iraq, Saudi Arabia, Kuwait, UAE, Qatar, and Bahrain, up from 7.5 million b/d in March. Brent crude oil spot prices averaged $103/b in March, with EIA projecting a peak of $115/b in Q2 2026 before easing below $90/b by Q4 2026 and averaging $76/b in 2027. Retail gasoline prices are forecast to peak at close to $4.30 per gallon in April, while diesel prices peak above $5.80/gal.

Routine Notice Energy
Spain CCN-CERT alt
Favicon for www.ccn-cert.cni.es

CCN-CERT AV 02/26 Critical Vulnerabilities in Citrix NetScaler ADC and Gateway

CCN-CERT issued alert AV 02/26 warning of two actively exploited critical vulnerabilities in Citrix NetScaler ADC and NetScaler Gateway products. CVE-2026-3055 allows memory exfiltration via SAML IDP profiles; CVE-2026-4368 enables session hijacking via race condition on VPN and AAA configurations. Affected versions span NetScaler ADC and Gateway 13.1 before 13.1-62.23 and 14.1 before 14.1-66.59. CCN-CERT recommends immediate patching, network access restrictions, and session termination following updates.

Urgent Guidance Cybersecurity
Singapore MTI News
Favicon for www.mti.gov.sg

Singapore and South America Reaffirm Bilateral Ties, Advance Carbon Credits and Agri-food Collaboration

Minister for Sustainability and the Environment Grace Fu concluded a ten-day official visit to South America covering Peru, Paraguay, and Chile from 13 to 22 April 2026. The visit reaffirmed bilateral ties and advanced collaboration on carbon credits and agri-food trade between Singapore and the three South American nations. A joint press release was issued by the Ministry of Trade and Industry and the Ministry of Sustainability and the Environment.

Routine Notice International Trade
Singapore MTI News
Favicon for www.mti.gov.sg

Singapore MAS Core Inflation 1.7% in March 2026

The Monetary Authority of Singapore (MAS) and Ministry of Trade and Industry (MTI) reported that MAS Core Inflation rose to 1.7% year-on-year in March 2026, up from 1.4% in February 2026, driven by increased retail and other goods and services inflation. On a month-on-month basis, core prices edged up by 0.1% in March. CPI-All Items inflation also picked up to 1.8% year-on-year from 1.2% in February, due to higher private transport and core inflation components.

Routine Notice Financial Services
Singapore MTI News
Favicon for www.mti.gov.sg

Singapore DPM Gan Keynote: Trade, AI, Energy Risks at CNBC Converge Live 2026

Singapore Deputy Prime Minister and Minister for Trade and Industry Gan Kim Yong delivered a keynote address at CNBC ConVERGE LIVE 2026 on April 22, discussing three forces reshaping the global economic landscape: trade fragmentation, rapid AI advancement, and the dual imperative of energy decarbonisation and security. He outlined Singapore's three strategic priorities for the next phase of growth: maintaining openness and connectivity across markets, scaling AI deployment in key sectors through AI Missions in advanced manufacturing, connectivity, financial services, and healthcare, and positioning early in the energy transition. The address noted that the Strait of Hormuz disruption has affected roughly a fifth of global oil flows, underscoring the immediacy of geopolitical supply chain risks.

Routine Notice International Trade
US DCMA News
Favicon for www.dcma.mil

Conco Plant Opens, Doubles MACS Output to 80,000 Monthly

Defense Contract Management Agency Lexington leaders attended the grand opening of Conco Inc.'s new industrial facility in Scottsburg, Indiana on February 5, 2026. The plant is dedicated to 155 mm Modular Artillery Charge System container production and will more than double the company's output to 80,000 MACS containers per month, supporting the Army's multi-year, $98 million contract. DCMA personnel will provide ongoing quality assurance oversight and contract administration throughout the product lifecycle, including oversight of the contractor's return site for container reuse.

Routine Notice Government Contracting
US DCMA News
Favicon for www.dcma.mil

DCMA Southeast Supports Army Infantry Squad Vehicle Acceptance, $90M Contract

Defense Contract Management Agency Southeast quality assurance specialists accepted 173 A1 Infantry Squad Vehicles at GM Defense LLC in Concord, N.C. on March 31, 2026, under a $90 million Army contract. The vehicles, priced between $156,000 and $400,000 depending on configuration, are being delivered to various military installations across the country. DCMA has delivered approximately 1,000 ISVs to the Army over the past five years. The team also oversees a $34 million Canadian Foreign Military Sales contract for Joint Light Tactical Vehicles, with approximately 135 Canadian vehicles inspected so far.

Routine Notice Government Contracting
Brazil MDIC News
Favicon for www.gov.br

Brazil Highlights NIB, Decarbonization and Critical Minerals at Hannover Messe

Brazil, as the official partner country of Hannover Messe 2026, showcased the Nova Indústria Brasil (NIB) industrial policy through seminars and panels. Secretary Uallace Moreira presented the six missions of NIB and highlighted policy instruments including the Plano Mais Produção and the Mover program for automotive sector decarbonization. The sessions covered sustainable aviation fuel, innovative decarbonization solutions, and Brazil-EU partnerships on critical minerals.

Routine Notice International Trade
Brazil MDIC News
Favicon for www.gov.br

Brazilian Trade Flows Reach US$ 12 Billion in Third Week of April

Brazil's trade balance recorded a weekly surplus of US$ 0.878 billion and trade flow of US$ 12 billion for the third week of April 2026, driven by exports of US$ 6.4 billion and imports of US$ 5.6 billion. For the full month through the third week, exports total US$ 21.2 billion and imports US$ 13.7 billion, yielding a cumulative surplus of US$ 7.5 billion with total trade flow of US$ 34.9 billion. Year-to-date exports stand at US$ 103.6 billion against imports of US$ 81.86 billion, producing a surplus of US$ 21.7 billion and trade flow of US$ 185.4 billion. Export sectors showed growth of 16.1% in agriculture, 29.9% in extractive industry, and 14.4% in manufacturing compared to the prior year period.

Routine Notice International Trade
Brazil MDIC News
Favicon for www.gov.br

Rodrigo Zerbone Appointed Executive Secretary at MDIC

Rodrigo Zerbone was named Executive Secretary of Brazil's Ministry of Development, Industry, Trade and Services (MDIC) on April 22, 2026. Zerbone previously led the Foreign Trade Chamber (Camex) and succeeds himself in government service since 2004. Juliana Volpi was appointed to replace Zerbone as Camex Executive Secretary, and James Elias was named Chief of Cabinet for Minister Márcio Elias Rosa, completing three senior personnel appointments at the ministry.

Routine Notice Government Contracting
Favicon for www.dpa.gr

Guidelines 1/2026 on Good Legislation for Personal Data Processing

The Hellenic Data Protection Authority (HDPA) published Guidelines 1/2026 on good legislation in relation to personal data processing, dated 10 March 2026. The guidelines require that when a legal rule establishes, permits, or presupposes personal data processing, compliance with specific principles and guarantees derived from EU and national constitutional law is mandatory. The guidelines mandate that drafting bodies consult the HDPA, particularly for high-risk processing, and provide a comprehensive checklist covering processing purpose, legal basis, roles, recipients, data categories, retention periods, data subject rights, security measures, and international transfers.

Routine Guidance Data Privacy
Favicon for ccb.belgium.be

Critical Improper Certificate Validation in Cisco Webex Allows User Impersonation (CVSS 9.8)

The Centre for Cybersecurity Belgium issued a critical security warning for CVE-2026-20184, an improper certificate-validation vulnerability (CWE-295) affecting Cisco Webex versions 39.6 through 45.4. The vulnerability carries a CVSS 9.8 score and enables remote, unauthenticated attackers to impersonate any user within the Cisco Webex service by supplying a crafted token during SSO with Control Hub, potentially compromising confidentiality, integrity, and availability. CCB strongly recommends installing vendor updates with highest priority and upscaling monitoring and detection capabilities to identify suspicious activity.

Urgent Guidance Cybersecurity
Favicon for ccb.belgium.be

OpenClaw Privilege Escalation CVE-2026-41329 Patched

The Centre for Cybersecurity Belgium has issued an urgent security advisory warning of CVE-2026-41329, a critical privilege escalation vulnerability in OpenClaw versions up to and including 2026.3.28 with CVSS 9.9. The flaw stems from improper context validation during heartbeat processing that allows attackers to bypass sandbox restrictions without credentials. CCB strongly recommends immediate patching to version 2026.3.31 and enhanced monitoring for suspicious activity.

Urgent Guidance Cybersecurity
Favicon for ccb.belgium.be

Critical Spinnaker RCE Vulnerabilities, CVSS 10.0, Patch Now

The Centre for Cybersecurity Belgium has issued a critical security advisory warning of two remote code execution vulnerabilities in Spinnaker, an open-source multi-cloud continuous delivery platform. CVE-2026-32613 and CVE-2026-32604 both carry a CVSS score of 10.0, the maximum severity rating, affecting expression parsing and gitrepo artifact type handling respectively. The vulnerabilities allow authenticated attackers to execute arbitrary code or access internal resources by exploiting insufficient input validation and improper sanitisation of user-controlled input such as branch names and file paths. CCB strongly recommends installing updates for vulnerable installations with the highest priority after thorough testing.

Urgent Guidance Cybersecurity
Favicon for www.cbcg.me

Central Bank Governors at Adria Future Summit Discuss Future of Digital Euro

Central bank governors from Montenegro, Slovenia, and Estonia participated in a panel at the Adria Future Summit 2026 to discuss the future of money in digital Europe, focusing on the digital euro and modern payment innovations. Governor Radović emphasized that early interoperability with new European financial systems is of strategic importance for Montenegro, noting the country's integration into SEPA and development of instant payment infrastructure aligned with the Eurosystem. Montenegro expressed strong interest in being considered as a pilot jurisdiction for the application of the digital euro in countries outside the euro area that use the euro.

Routine Notice Banking
Japan JETRO News
Favicon for www.jetro.go.jp

FY2025 Survey on Business Conditions of Japanese Companies in North America

JETRO published results from its FY2025 annual survey of Japanese companies operating in the U.S. and Canada, receiving 735 responses (652 from the U.S., 83 from Canada) out of 2,058 sent, a 35.7% response rate. For 2025, 66.5% of Japanese companies in the U.S. and 80.5% in Canada expect to turn a profit, with Canada's figure reaching the highest since 2000. U.S. business sentiment dropped to its lowest since 2020 due to tariff-related cost increases and economic uncertainty. Regarding supply chains, 88 Japanese companies in the U.S. reported shifts to domestic U.S. sourcing, more than double the previous year's figure, with 45 shifting from Japan and 23 from China to the U.S.

Routine Notice International Trade
Japan JETRO News
Favicon for www.jetro.go.jp

2025 Survey on Business Operations of Foreign-Affiliated Companies in Japan

JETRO has published findings from its 2025 Survey on Business Operations of Foreign-Affiliated Companies in Japan, covering responses from 1,520 companies (valid response rate of 19.7%) out of 7,698 surveyed. The survey finds that approximately 60% of foreign-affiliated companies intend to strengthen or expand their operations in Japan, with social and economic/geopolitical stability now the most highly rated aspect of Japan's business environment since the survey began. Nearly 40% of respondents expect negative impacts from U.S. tariff policy in both the short and long term.

Routine Notice International Trade
Japan JETRO News
Favicon for www.jetro.go.jp

Japan, Arizona Sign MOU for Semiconductor R&D Collaboration

JETRO, Arizona State University, the Arizona Commerce Authority, and the Greater Phoenix Economic Council signed a Memorandum of Understanding on March 4, 2026, establishing a framework for collaboration in semiconductor R&D, human resource development, and workforce development. The agreement leverages JETRO's nationwide network of Japan's regional industrial ecosystems, ASU's research expertise, and ACA and GPEC's networks of Arizona-based companies to support industrial ecosystem development in both regions. Key initiatives include jointly organizing symposiums, seminars, and business missions, and implementing collaborative programs with Japan's domestic semiconductor ecosystem.

Routine Notice International Trade
OR DOT News
Favicon for www.oregon.gov

Night Work on OR 126 Springfield, April 26

Crews will begin crack sealing on OR 126 between mileposts 10 and 15 in Springfield starting Sunday, April 26, 2026. Work will occur Sunday through Wednesday, 7 p.m. to 5:30 a.m., with intermittent lane closures in both directions and delays expected through the work zone. Drivers should watch for flaggers and pilot cars and plan extra travel time.

Routine Notice Transportation
Favicon for changeflow.com

Obrixtamig Phase 3 Trial for Advanced Extrapulmonary Neuroendocrine Cancer

NCT07544654 is a Phase 3 clinical trial registering adults with advanced extrapulmonary neuroendocrine cancer. The treatment arm receives obrixtamig plus standard chemotherapy (carboplatin and etoposide) followed by obrixtamig alone for up to 3 years, while the control arm receives standard chemotherapy alone for approximately 4 months. The trial also evaluates the Ventana DLL3 RxDx assay as a companion diagnostic device. The study is designated to begin on April 22, 2026.

Routine Notice Pharmaceuticals
Favicon for changeflow.com

BrainLive Connect Volunteer Training Programme for Dementia

This is a clinical trial registration for NCT07544875, a mixed-method randomized controlled trial evaluating BrainLive Coach training among adults aged 50 and over. The trial will compare 80-90 hours of BrainLive Coach training followed by BrainLive Connect volunteering against educational materials on dementia and cognitive health. Participants will be assessed at baseline and post-intervention on dementia knowledge, competence in dementia care, self-efficacy, attitudes to dementia, quality of life, and social capital. Qualitative interviews and focus groups with trained volunteers and NGO staff will explore perceived impacts, mechanisms, and implementation barriers.

Routine Notice Healthcare
Favicon for changeflow.com

Modified Dahuang Mouthwash, Phase 3, RTOM Prevention

A multicenter, randomized, controlled, prospective Phase 3 clinical trial (NCT07543978) is registered under NIH ClinicalTrials.gov to evaluate the safety and efficacy of Modified Dahuang Huanglian Xiexin Mouthwash versus Placebo Mouthwash for the prevention of radiotherapy-induced oral mucositis (RTOM) in patients undergoing radiotherapy. The trial is classified as Phase 3 with an anticipated start date of April 22, 2026.

Routine Notice Pharmaceuticals
Favicon for changeflow.com

Carb Loading Reduces Insulin Resistance in Pediatric Surgery

A double-blinded randomized controlled trial examining the effect of preoperative carbohydrate loading on preventing postoperative insulin resistance in pediatric patients undergoing elective surgery. The interventional study registered on ClinicalTrials.gov compares carbohydrate loading to water placebo, with insulin resistance as the primary condition studied.

Routine Notice Healthcare
Favicon for changeflow.com

Navicular Mobilization in Patients of Planter Fasciitis RCT

This randomized clinical trial registration on ClinicalTrials.gov describes a study to compare navicular mobilization versus conventional physical therapy with navicular mobilization for treating plantar fasciitis. The trial will enroll 48 participants (24 per group) at University of Lahore Teaching Hospital, Pakistan. Treatment consists of 4 sessions per week for 4 weeks (16 total sessions), with assessments at baseline, week 2, and week 4. ClinicalTrials.gov serves as the registration platform; the trial is listed under identifier NCT07544901.

Routine Notice Healthcare
Favicon for changeflow.com

Periosteal Distraction With Skin Grafting for DFU, 104-Patient Randomized Trial

A single-center, prospective, randomized controlled trial registered on ClinicalTrials.gov (NCT07545668) will evaluate whether periosteal distraction combined with autologous split-thickness skin grafting improves graft survival at postoperative day 14 compared with skin grafting alone in 104 patients with diabetic foot ulcers (Wagner grade 2-3 or post-amputation). Participants are randomized 1:1 into experimental (n=52) and control (n=52) groups, with secondary outcomes including time to complete epithelialization, wound healing quality (BWAT score at 3 months), ulcer recurrence at 6 months, foot function (AOFAS score), quality of life (DFS-SF score), and safety profile. The study addresses poor graft survival in ischemic wound environments and aims to establish a novel minimally invasive treatment paradigm for diabetic foot ulcers.

Routine Notice Healthcare
Favicon for changeflow.com

Pediatric Renal Emergencies: Presentations and Outcomes at Sohag University Hospitals

A prospective cohort study registered on ClinicalTrials.gov (NCT07543549) investigating pediatric renal emergencies at Sohag University Hospitals in Upper Egypt. The observational study aims to characterize clinical presentations of renal diseases among children presenting to the emergency room, determine prevalence of specific renal conditions, and evaluate immediate management outcomes and short-term follow-up after discharge. Expected primary completion date is April 22, 2026.

Routine Notice Public Health
Favicon for changeflow.com

Assessment of IOP After Corneal Refractive Surgery Based on AI

NCT07544615 is an observational study registered on ClinicalTrials.gov assessing intraocular pressure (IOP) changes after corneal refractive surgery using artificial intelligence. The study, registered by NIH on April 22, 2026, examines conditions including myopia, astigmatism, and refractive surgery outcomes. Clinical investigators will monitor approximately 100 participants to evaluate how corneal biomechanical changes affect IOP readings with various tonometers.

Routine Notice Public Health
Favicon for changeflow.com

CHOP Phase 2 Alpelisib Trial for Vascular Anomalies

NIH ClinicalTrials.gov registers a Phase 2 single-site trial at Children's Hospital of Philadelphia (Philadelphia Campus) evaluating Alpelisib (BYL719) in patients aged 2 months to 30 years with TIE2/PIK3CA pathway-driven vascular anomalies. The study will enroll approximately 24 participants, who must complete up to 16 clinic visits over a participation period of up to 3 years, with at least 2 years of continuous study-drug administration. Alpelisib is FDA-approved for certain breast-cancer indications but is used experimentally here, as no VA indication has received regulatory approval.

Routine Notice Pharmaceuticals
Favicon for changeflow.com

rPMS for Chronic Elbow, Wrist Pain, 40 Participants, Apr 22

This pilot, randomized, sham-controlled, single-blind study will evaluate the effectiveness of repetitive peripheral magnetic stimulation (rPMS) in reducing pain in adults with tennis/golfer's elbow or carpal tunnel syndrome. Approximately 40 participants will be randomly assigned to active or sham stimulation delivered over two consecutive days. Outcomes, including pressure pain threshold, subjective pain ratings, and local tissue oxygenation (fNIRS), will be assessed at baseline, immediately post-intervention, and during follow-up up to 6 months to evaluate both clinical effects and underlying physiological mechanisms.

Routine Notice Healthcare
Saudi SFDA News
Favicon for www.sfda.gov.sa

King Saud University Innovation Exhibition Showcases SFDA RDI Initiatives

The Saudi Food and Drug Authority showcased its research, development, and innovation initiatives at the World Creativity and Innovation Day Exhibition held at King Saud University's Innovation Center from April 21 to 23, 2026. The SFDA highlighted two programs: the Innovative Medical Devices Initiative providing technical and regulatory guidance for marketing authorization, and the Breakthrough Medicines Initiative aimed at accelerating access to advanced therapies. The exhibition united SFDA with the Royal Commission for Riyadh City, the Research Development and Innovation Authority, and the Digital Government Authority, reflecting SFDA's commitment to Saudi Vision 2030.

Routine Notice Healthcare
Favicon for www.meti.go.jp

Minister Akazawa Attends G7 Energy and Finance Ministers Online Meeting

Minister Akazawa Ryosei of Japan's Ministry of Economy, Trade and Industry attended the G7 Energy and Finance Ministers and Central Bank Governors online meeting held on March 30, 2026, chaired by France. Also attending from Japan were Finance Minister Katayama Satsuki and Bank of Japan Governor Ueda Kazuo, alongside representatives from IEA, IMF, World Bank, and OECD. Participants discussed the impact of the Middle East situation on global energy supply, demand, and economic activities, resulting in a joint statement.

Routine Notice Energy

Showing 4051–4100 of 25,000 changes

1 80 81 82 83 84 500

Get daily regulatory alerts

Daily digest delivered to your inbox.

Free. Unsubscribe anytime.

Browse by country

United States

2658 sources

United Kingdom

261 sources

European Union

130 sources

Canada

77 sources

International

60 sources

Australia

55 sources

India

41 sources

Japan

32 sources

France

30 sources

Germany

27 sources

Singapore

27 sources

GLOBAL

23 sources

Italy

21 sources

Netherlands

17 sources

Poland

16 sources

Switzerland

15 sources

Ireland

15 sources

Spain

14 sources

Hong Kong

14 sources

New Zealand

14 sources

South Korea

13 sources

Brazil

13 sources

South Africa

12 sources

Norway

12 sources

Sweden

11 sources

Finland

8 sources

China

8 sources

Colombia

8 sources

Türkiye

8 sources

Austria

8 sources

Denmark

8 sources

UAE

7 sources

Luxembourg

7 sources

Malta

7 sources

UK

7 sources

Belgium

7 sources

Ghana

6 sources

Sri Lanka

6 sources

Greece

6 sources

Taiwan

6 sources

Chile

6 sources

Egypt

5 sources

Romania

5 sources

Cyprus

5 sources

Hungary

5 sources

Kenya

4 sources

Malaysia

4 sources

Argentina

4 sources

Mexico

4 sources

Estonia

4 sources

Croatia

4 sources

Nigeria

4 sources

Mauritius

3 sources

Pakistan

3 sources

Nepal

3 sources

Russian Federation

3 sources

Israel

3 sources

Czechia

3 sources

Thailand

3 sources

Bulgaria

3 sources

Saudi Arabia

3 sources

Guernsey

2 sources

Honduras

2 sources

Panama

2 sources

Uzbekistan

2 sources

Gibraltar

2 sources

Iceland

2 sources

Ecuador

2 sources

Kyrgyzstan

2 sources

Slovenia

2 sources

Cayman Islands

2 sources

Philippines

2 sources

Vietnam

2 sources

Albania

2 sources

El Salvador

2 sources

Barbados

2 sources

Costa Rica

2 sources

Slovakia

2 sources

Botswana

2 sources

Kazakhstan

2 sources

Tanzania

2 sources

Jordan

2 sources

Bangladesh

1 sources

Bahamas

1 sources

Morocco

1 sources

Indonesia

1 sources

Montenegro

1 sources

Rwanda

1 sources

Bosnia and Herzegovina

1 sources

Isle of Man

1 sources

Peru

1 sources

Serbia

1 sources

Zambia

1 sources

Zimbabwe

1 sources

Latvia

1 sources

Saint Kitts and Nevis

1 sources

Paraguay

1 sources

Maldives

1 sources

Bhutan

1 sources

Armenia

1 sources

Portugal

1 sources

Tunisia

1 sources

Iraq

1 sources

Uganda

1 sources

Vanuatu

1 sources

Ethiopia

1 sources

XX

1 sources

Venezuela

1 sources

Liechtenstein

1 sources

Namibia

1 sources

Samoa

1 sources

Oman

1 sources

Fiji

1 sources

Turks and Caicos Islands

1 sources

Azerbaijan

1 sources

Anguilla

1 sources

Myanmar

1 sources

Lebanon

1 sources

Bermuda

1 sources

Virgin Islands, British

1 sources

Moldova

1 sources

Malawi

1 sources

Tonga

1 sources

Get alerts when regulations change

Weekly digest. AI-summarized, no noise.

Free. Unsubscribe anytime.