USPTO Patent Application: Treating NSCLC with Dostarlimab or Biosimilar

The USPTO has published a patent application detailing a method for treating non-small cell lung cancer (NSCLC) using dostarlimab or a biosimilar. The application outlines a treatment approach for patients previously treated with an immune checkpoint inhibitor.

USPTO Patent Application: NEO-201 Antibody for Suppressing Myeloid Derived Suppressor Cells

The USPTO has published a patent application (US20260083840A1) detailing methods for ablating myeloid derived suppressor cells using the NEO-201 antibody. The application describes the antibody's specific binding to certain O-glycans and its potential use in treating cancers and infectious diseases by suppressing gMDSCs.

Bispecific Molecule Stabilizing Composition Patent Application

The USPTO has published a patent application (US20260083841A1) for a pharmaceutical composition designed to stabilize bispecific antigen-binding molecules at increased concentrations. The composition includes buffer agents, saccharides, and specific stabilizing agents like EDTA or citric acid.

USPTO Patent Application: IL-17 Antibody Compositions

The USPTO has published a patent application (US20260083842A1) detailing pharmaceutical products and stable liquid compositions of IL-17 antibodies, such as secukinumab. The application covers methods of making these compositions and their use in treating IL-17-mediated disorders, including autoimmune conditions like psoriasis and rheumatoid arthritis.

USPTO Patent Application for Anti-PD-1 Antibody-IL-2 Immunoconjugate Formulations

The USPTO has published a new patent application (US20260083857A1) for anti-PD-1 antibody-IL-2 immunoconjugate formulations. The application details stable pharmaceutical formulations comprising anti-human PD-1 antibody-modified human interleukin-2 immunoconjugates.

USPTO Patent Application: Antibody Drug Conjugate Comprising NMT Inhibitor

The USPTO has published a new patent application (US20260083858A1) related to antibody drug conjugates (ADCs) that comprise an NMT inhibitor conjugated to an antibody via a linker. The application details the inventors and abstract of the invention.

Emergency Sirens Test Scheduled for April 7

The Delaware Division of Public Health announced a scheduled test of emergency sirens for Tuesday, April 7, 2026, at 7:20 PM. This test is part of the state's emergency preparedness measures, particularly concerning the Salem/Hope Creek Nuclear Generating Station.

MDE Approves Air Permit for Frederick Data Center

The Maryland Department of the Environment (MDE) has approved an air quality permit for Amazon Data Services, Inc. for emergency backup generators at a new data center campus in Frederick. The permit ensures generators will only be used during emergencies and includes continuous oversight under the Clean Air Act.

ICO fines TMAC Ltd £100,000 for PECR breaches

The UK's Information Commissioner's Office (ICO) has fined TMAC Ltd £100,000 for breaches of the Privacy and Electronic Communications Regulations (PECR). The company made over 260,000 unsolicited marketing calls to individuals registered on the Telephone Preference Service and failed to provide required caller information.

EPA Authorizes Florida Hazardous Waste Program Revisions

The EPA has granted final authorization for revisions to Florida's hazardous waste management program under RCRA. This action is effective May 26, 2026, unless adverse comments are received by April 27, 2026. The revisions were submitted by Florida on September 1, 2023.

Florida Hazardous Waste Program Revisions Authorized by EPA

The EPA is proposing to authorize revisions to Florida's hazardous waste management program. This action would allow Florida to implement and enforce these revised program elements under the Resource Conservation and Recovery Act (RCRA). The public comment period for this proposed rule closes on April 27, 2026.

EPA Seeks Comment on Clean Water Act Financial Capability Guidance

The Environmental Protection Agency (EPA) is seeking public comment on draft guidance for assessing financial capability under the Clean Water Act (CWA). This guidance aims to help states and tribes evaluate the financial capacity of entities to comply with water quality standards and permits.

EPA Modifies Privacy Act System of Records

The EPA is proposing to modify a Privacy Act system of records to add a new routine use as required by Executive Order 14249 and OMB Memorandum M-25-32. The agency is also updating contact information for the Agency Privacy Officer. The comment period for this notice closes on April 27, 2026.

EPA TSCA Confidential Business Information Renewal for OMB Review

The Environmental Protection Agency (EPA) has submitted a renewal request for its collection of TSCA Confidential Business Information (CBI) to the Office of Management and Budget (OMB) for review and approval. This notice provides an opportunity for public comment on the information collection activities.

EPA Approves Iowa Air Quality Regulations Revisions

The Environmental Protection Agency (EPA) has published a proposed rule to approve revisions to Iowa's air quality regulations. This action is part of the EPA's review process for state implementation plans under the Clean Air Act. The public has a comment period to provide input on the proposed approval.

EPA Proposes Hazardous Waste Delisting for WRB Refining

The Environmental Protection Agency (EPA) has proposed to delist hazardous waste generated by WRB Refining from the hazardous waste regulations under the Resource Conservation and Recovery Act (RCRA). This proposed rule is open for public comment.

Energy Conservation Program: Representative Average Unit Costs of Energy

The Department of Energy has published a notice regarding the representative average unit costs of energy for consumer products. These updated costs will become effective on April 27, 2026, and will remain in effect until further notice.

National Cooperative Research Act: MLCommons Association Membership Changes

The DOJ Antitrust Division has published a notice regarding changes to the membership of MLCommons Association under the National Cooperative Research and Production Act of 1993. Several new members have been added, and two members have withdrawn from the association.

DOJ Notice on Biopharmaceutical Manufacturing Preparedness Consortium Membership Changes

The DOJ Antitrust Division published a notice regarding changes to the membership of the Biopharmaceutical Manufacturing Preparedness Consortium (BIOMAP-CONSORTIUM). The consortium filed notifications disclosing new parties added to the group research project, which is intended to extend the National Cooperative Research and Production Act's provisions limiting antitrust plaintiff recovery to actual damages.

ODVA, Inc. Membership Changes Under National Cooperative Research Act

The Antitrust Division published a notice regarding ODVA, Inc. under the National Cooperative Research and Production Act. ODVA reported changes in its membership, adding two foreign parties and removing four foreign parties from its research venture. This notice serves to maintain the limitations on antitrust damages for the venture.

1EdTech Consortium Membership Changes Under National Cooperative Research Act

The Antitrust Division has published a notice regarding changes in membership for the 1EdTech Consortium, Inc., filed under the National Cooperative Research and Production Act of 1993. Several new members have joined, and others have withdrawn from the consortium.

DOJ Antitrust: National Cooperative Research and Production Act - Rust Foundation Membership Changes

The DOJ Antitrust Division has published a notice regarding changes to the Rust Foundation's membership under the National Cooperative Research and Production Act of 1993. Three new members have joined, and one has withdrawn from the research venture. This notice serves to update the record and maintain the limitations on antitrust plaintiff recovery.

National Cooperative Research Act: Cable Television Laboratories Membership Change

The DOJ Antitrust Division has published a notice regarding changes to Cable Television Laboratories, Inc.'s membership under the National Cooperative Research and Production Act of 1993. Boycom Cablevision, Inc. has been added as a party to the venture, with no other changes to membership or planned activities.

National Cooperative Research Act Notice - Pistoia Alliance, Inc.

The Department of Justice's Antitrust Division has published a notice regarding Pistoia Alliance, Inc. under the National Cooperative Research and Production Act of 1993. This notice serves as an informational filing related to the organization's research and production activities.

Notice Pursuant to the National Cooperative Research and Production Act of 1993 - National Fire Protection Association

The Department of Justice's Antitrust Division has published a notice regarding the National Fire Protection Association's compliance with the National Cooperative Research and Production Act of 1993. This notice serves to inform the public of the association's stated intent to engage in cooperative research and development activities.

National Cooperative Research Act - Z-Wave Alliance, Inc. Notice

The Department of Justice's Antitrust Division published a notice regarding Z-Wave Alliance, Inc. under the National Cooperative Research and Production Act of 1993. This notice serves as a public announcement of the alliance's formation and its stated research and production activities.

National Cooperative Research Act - TeleManagement Forum Notice

The Department of Justice's Antitrust Division has published a notice regarding the TeleManagement Forum (TM Forum) under the National Cooperative Research and Production Act of 1993. This notice serves as a public announcement of the forum's formation and its intent to engage in research and development activities.

Notice Pursuant to the National Cooperative Research and Production Act - OpenGMSL Association

The Department of Justice's Antitrust Division published a notice regarding the National Cooperative Research and Production Act of 1993 concerning the OpenGMSL Association. This notice serves as a formal announcement related to cooperative research and production activities.

DOJ Antitrust Division Notice on National Advanced Mobility Consortium Membership Changes

The Department of Justice's Antitrust Division has published a notice regarding changes in the membership of The National Advanced Mobility Consortium, Inc. (formerly Robotics Technology Consortium). This notice is filed pursuant to the National Cooperative Research and Production Act of 1993 to extend provisions limiting antitrust plaintiff recovery to actual damages.

Notice of National Cooperative Research and Production Act Mercury Consortium

The Department of Justice's Antitrust Division published a notice regarding the Mercury Consortium under the National Cooperative Research and Production Act of 1993. This notice serves as an informational filing for a research and production joint venture.

DOJ Antitrust Division Notice on America's Datahub Consortium

The Department of Justice's Antitrust Division has published a notice regarding the America's Datahub Consortium under the National Cooperative Research and Production Act of 1993. This notice serves to inform the public about the formation and purpose of this consortium.

National Cooperative Research Act - OpenJS Foundation Notice

The Department of Justice's Antitrust Division has issued a notice regarding the OpenJS Foundation under the National Cooperative Research and Production Act of 1993. This notice serves as an informational filing related to the foundation's research and production activities.

ASTM International Cooperative Research Notice

The DOJ Antitrust Division has published a notice regarding ASTM International's updated list of standards development activities. This notice is filed pursuant to the National Cooperative Research and Production Act of 1993 to maintain limitations on antitrust plaintiff recovery to actual damages.

R Consortium Inc. - Membership Change Notice

The DOJ Antitrust Division published a notice regarding R Consortium, Inc. under the National Cooperative Research and Production Act. The notice discloses changes in membership, specifically the withdrawal of Oracle Corporation, Google, and Genentech, Inc. from the venture.

UK Capital Issuance Statistics - February 2026

The Bank of England reported that UK capital issuance in February 2026 was £68.4 billion, a decrease from £70.8 billion in January, primarily due to lower commercial paper issuance. Net issuance also saw a slight reduction to £16.4 billion. Bond issuance increased, while equity issuance remained low.

Bank of England Streamlines Bank Failure Reporting and Disclosure

The Bank of England and Prudential Regulation Authority have finalised changes to bank resolution reporting and disclosure requirements. These updates increase the threshold for resolution assessment reporting and simplify MREL reporting and Pillar 3 disclosures, aiming to reduce regulatory burden for smaller firms while maintaining a robust regime for larger institutions.

Rwangoko Andrew v. Kristi Noem - Immigration Case Stayed

The U.S. District Court for the Western District of Washington has stayed proceedings in Rwangoko Andrew v. Kristi Noem, et al. until April 22, 2026. The plaintiff seeks to compel USCIS to adjudicate pending I-730 Refugee/Asylee Relative Petitions filed in December 2018.

CPX26 v State of New South Wales - Interlocutory Orders Dismissed, Non-Publication Allowed

The Federal Court of Australia dismissed interlocutory orders sought by the applicants in CPX26 v State of New South Wales. However, the court allowed in part applications for non-publication, suppression, and pseudonym orders under section 37AF of the Federal Court of Australia Act 1976.

BJJ18 v Minister for Immigration and Citizenship - Judicial Review Dismissal

The Federal Court of Australia dismissed the application for an extension of time to appeal in BJJ18 v Minister for Immigration and Citizenship. The applicant failed to appear at the hearing and had not filed required documents, leading to the dismissal and an order for costs. The decision affirms the dismissal of judicial review proceedings related to a protection visa application.

Davis v M.G. O'Brien Investments Pty Ltd - Bankruptcy Case

The Federal Court of Australia has refused an urgent application to adjourn a bankruptcy notice compliance extension hearing and dismissed the applicants' interim application. The applicants were ordered to pay the respondents' costs for the interim application.

Staunton v Zahab - Interim Control Order

The Federal Court of Australia has issued an interim control order against Haisem Zahab, who has been convicted of a terrorism offense and is nearing release. The order, made under s 104.4 of the Criminal Code, is deemed reasonably necessary to manage the risk posed by the respondent. A confirmation hearing is scheduled for June 1, 2026.

EKY17 v Minister for Immigration, Citizenship and Multicultural Affairs - Migration Visa Appeal

The Federal Court of Australia dismissed an appeal concerning a protection visa refusal. The court found no jurisdictional error and upheld the primary judge's refusal to grant an adjournment for legal representation, concluding there was no denial of procedural fairness. The appellants were ordered to pay the respondent's costs.

Tabcorp Maxgaming Holdings tax deduction appeal judgment

The Federal Court of Australia dismissed an appeal by Tabcorp Maxgaming Holdings Limited against the Commissioner of Taxation. The appeal concerned the deductibility of a loss claimed under Division 230 of the Income Tax Assessment Act 1997, specifically whether the appellant had a 'financial arrangement'. The court upheld the primary judge's decision.

Leave to Proceed Granted in Corporations Act Liquidation Case

The Federal Court of Australia granted leave for the Secretary of the Department of Health, Disability and Ageing to proceed against AG Therapeutics Pty Ltd, which is in liquidation. The case involves alleged contraventions of the Therapeutic Goods Act 1989 (Cth).

CVH17 v Minister for Immigration - Protection Visa Appeal Dismissed

The Federal Court of Australia dismissed an appeal by CVH17 against a decision to refuse a Protection visa. The court found the grounds of appeal to be without merit and ordered the appellant to pay the first respondent's costs. The appeal was from a decision of the Federal Circuit and Family Court of Australia.

Lo v Minister for Immigration and Citizenship - Migration Case

The Federal Court of Australia dismissed an appeal by Thi Kim Loan Lo against a decision to affirm the mandatory cancellation of her visa. The court found no error in the Administrative Review Tribunal's consideration of generalized harm from drug trafficking, upholding the visa cancellation.

ACCC v Qteq - $5M and $1M Penalties Imposed for Cartel Conduct

The Federal Court of Australia has imposed penalties of $5 million and $1 million on Qteq Pty Ltd and its related entity respectively for contraventions of cartel prohibitions under the Competition and Consumer Act 2010. The court also made a non-indemnification order against the second respondent.

JVZ25 v Minister for Immigration and Citizenship - Injunctive Relief Dismissed

The Federal Court of Australia dismissed an urgent interlocutory application for injunctive relief to restrain the removal of an applicant pending an appeal. The applicant sought to prevent removal from Australia while appealing a prior decision regarding immigration. The court ordered the dismissal of the application and awarded costs to the respondent.

Corporations Act Case: Winding Up, Disclaimer, Revesting Property

The Federal Court of Australia has issued a judgment regarding the winding up and disclaimer of property under the Corporations Act 2001. The court ordered the revesting of specific tenements back to Kalium Lakes Potash Pty Ltd (in liq) to facilitate their sale, as no other party opposed the application.

So v Minister for Immigration and Citizenship - Judicial Review of Visa Cancellation

The Federal Court of Australia allowed a judicial review of a visa cancellation decision, quashing the Administrative Review Tribunal's affirmation of the cancellation. The case has been remitted to the Tribunal for redetermination according to law. The respondent, the Minister for Immigration and Citizenship, was ordered to pay the applicant's costs.