ChangeBridge: Patent Apps - Peptides (C07K)

USPTO Patent Application: Orthogonal Mutations for Heterodimerization

The USPTO has published a patent application (US20260078202A1) detailing orthogonal mutations for heterodimerizing domains, particularly in antibody CH3 domains. This application, filed on April 25, 2025, by Jonathan Harry Davis and Nicholas M. Marshall, describes heterodimeric polypeptides and antibody constructs.

USPTO Patent Application for Multivalent CLTX-CAR γδ T-cells

The USPTO has published a patent application (US20260078529A1) for multivalent CLTX-CAR γδ T-cells, which are designed for treating cancer or tumors. The application details specific T-cell compositions, pharmaceutical formulations, and methods of co-administering these cells with chemotherapeutic agents.

USPTO Patent Application for Tau Phospho Binding Antibodies

The USPTO has published a patent application (US20260079168A1) for Tau phospho binding antibodies and antigen binding fragments thereof. The application, filed on September 15, 2025, relates to methods for detecting Tau phospho (Thr217) and potential diagnostic or therapeutic uses for diseases associated with it.

USPTO Patent Application: Pathogen Surrogates for Fresh Produce Sanitation

The USPTO has published a patent application (US20260079142A1) detailing pathogen surrogates with DNA tags for verifying sanitation systems in fresh produce processing. The application describes a method using these surrogates to mimic pathogen behavior during sanitation and subsequent DNA detection.

USPTO Patent Application: Ultrasensitive Immunoassay Method and Reagents

The USPTO has published a patent application detailing a new method and reagents for ultrasensitive detection of target molecules using reconstituted functional proteins. The invention aims to improve specificity and signal-to-noise ratios in various assay formats, including those for detecting viruses, bacteria, and proteins.