Patent Application for GYS1 Inhibitors

The USPTO has published a patent application (US20260085034A1) for N-(BENZHYDRYL)CYCLOALKYLCARBOXAMIDE derivatives as inhibitors of Glycogen Synthase 1 (GYS1). The application details compounds and methods for preparing them, as well as methods for inhibiting GYS1 and treating GYS1-mediated diseases.

Patent Application for Psilocin Derivatives for Treating Disorders

The USPTO has published a patent application (US20260085040A1) for psilocin derivatives, including carbohydrate and amino acid conjugates. These compounds are intended for the treatment of various neuropsychiatric, neurodegenerative, neuroinflammatory, and pain disorders.

Patent Application for Chromophores with New Ring-Locked Donors

The USPTO has published a new patent application (US20260085189A1) filed by Lightwave Logic, Inc. The application describes novel nonlinear optical (NLO) chromophores with ring-locked donors designed to increase r33 and stability. The filing date was September 23, 2025.

Patent Application for NLO Chromophores with New Acceptors

The USPTO has published a patent application (US20260085190A1) filed by Lightwave Logic, Inc. The application describes nonlinear optical (NLO) chromophores designed to increase refractive index, offering advantages in speed, photostability, and thermal stability for electro-optic devices.

Patent for Heterocyclic Compound Organic Light Emitting Device

The USPTO has published a patent application for a heterocyclic compound intended for use in organic light-emitting devices. The application, filed by Eui-Jeong Choi and others, describes a compound that may improve device efficiency and lifespan.

Patent Application: Organic Light Emitting Device Compound

The USPTO has published a new patent application, US20260090199A1, detailing a novel organic compound for use in organic light-emitting devices. The application describes a compound that may offer improved driving voltage, efficiency, and service life compared to existing technologies.

Mitsubishi Gas Chemical Organic Thin Film Patent Application

The USPTO has published a new patent application from Mitsubishi Gas Chemical Company, Inc. for a compound and organic thin film technology. The application, filed on December 14, 2023, details a specific molecular structure intended for use in photoelectric conversion elements and imaging devices.

Organic electronic element and compound for improved hole transport

The USPTO has published a new patent application, US20260090270A1, filed by TOSOH CORPORATION. The application describes an organic electronic element and a compound designed to improve hole transport ability, potentially enhancing performance in electronic devices.

Organic Compound and Light-Emitting Device Patent Application

The USPTO has published a patent application (US20260090268A1) for an organic compound and a light-emitting device incorporating it. The application details specific chemical structures and their application in electronic apparatus. The filing date was September 8, 2025.

Patent Application for Cancer Treatment Compounds

The USPTO has published a new patent application (US20260085070A1) for heterocyclic CBL-B inhibitors intended for the treatment of cancer. The application was filed on April 7, 2025, by inventors Yingzhi BI, Kenneth G. CARSON, and Geraldine Cirillo HARRIMAN.

Patent Application for Novel Crystalline Form of Amine Compound

The USPTO has published a patent application (US20260085071A1) for novel crystalline forms of an amine compound, 1-(8-bromopyrido[2,3-e][1,2,4]triazolo[4,3-a]pyrazin-4-yl)-N-methylazetidin-3-amine. The application also discloses pharmaceutical compositions and the use of these forms for treating diseases such as atopic dermatitis and urticaria.

Protein Degraders Patent Application

The USPTO has published a new patent application, US20260085075A1, related to protein degraders and their uses. The application was filed on August 19, 2025, by inventors Nello Mainolfi, Nan Ji, Yi Zhang, and Matthew M. Weiss.

Patent Application for Novel Compound Treating Neurodegeneration and Cardiovascular Diseases

The USPTO has published a patent application (US20260085083A1) for a novel compound and pharmaceutical composition developed by SHANDONG RUZHI BIOMEDICINE TECHNOLOGY CO., LTD. The compound is intended for preventing or treating neurodegenerative diseases and cardiovascular/cerebrovascular diseases.

New Polymers and Methods Patent Application

The USPTO has published a new patent application, US20260085336A1, detailing processes for forming pyridinedicarboxylic acid derivatives and copolymers. The application, filed on September 25, 2025, outlines biocatalytic methods and potential uses for these new materials.

Novel Nootropic Prodrugs of Phenethylamine

The USPTO has published a patent application (US20260085036A1) for novel nootropic prodrugs of phenethylamine, assigned to MiHKAL GmbH. The application describes compounds designed to improve phenethylamine uptake and reduce side effects, potentially for treating conditions like depression and PTSD.

Psilocin Crystalline Forms Patent Application

The USPTO has published a patent application (US20260085039A1) detailing crystalline forms of psilocin, including salts and cocrystals. The application, filed by Jim Gilligan and Peter Guzzo, describes these forms as having improved physical properties like aqueous solubility and stability, suitable for various administration routes.

Photoresist Molecular Group Structure, Synthesis, and Use Method

The USPTO has published a new patent application (US20260086460A1) for a bifunctional molecular group structure for photoresists, including a linker, PAG molecule, and PDQ molecule. The application also details synthesis and use methods for this structure, assigned to Shanghai Huali Integrated Circuit Corporation.

US Patent Application: Non-Aqueous Electrolyte, Battery, Device

The USPTO has published a new patent application (US20260088357A1) for a non-aqueous electrolyte, secondary battery, and electric device. The application, filed by CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED, details specific chemical compositions for electrolytes, including cyclic sulfate compounds and organic base additives. This publication represents a new disclosure in the field of battery technology.

Substituted Indazoles for Treating Animal Allergic Inflammatory Diseases

The USPTO has published a patent application detailing the use of substituted indazoles for the treatment and prevention of allergic and inflammatory diseases in animals. The application, filed on October 9, 2025, outlines specific compounds and their potential applications in veterinary medicine.

EPO Patent Bulletin: Medical Devices & Diagnostics

The European Patent Office's latest patent bulletin lists new publications and grants related to medical devices and diagnostics under the A61B classification. The bulletin includes details on inventions such as apparatus for forming bone canals, surgical microscope systems, and methods for imaging and biomarker detection, with publication dates in March 2026.

Device for Delivering Antimicrobial Composition into Medical Device

The USPTO has published a patent application (US20260083952A1) for a device cap designed to deliver an antimicrobial composition into a medical device. The application details a male cap with a water-soluble antimicrobial composition, potentially covered by a slower-dissolving material to control dissolution during installation.

Implantable Medical Device Tubing Management Patent Application

The USPTO has published a new patent application (US20260083951A1) for an implantable medical device featuring a novel tubing management system. The application details a tube retainer designed to secure portions of the tubing connecting various components of the device.

US Patent Application for Needle Locator and Guide

The USPTO has published a new patent application (US20260083950A1) for an apparatus designed to locate a target structure within a subject's body and guide a needle at a specific angle. The application was filed on September 1, 2023, by inventors Wim Bervoets, Daniel Smyth, Wolfram Frederik Dueck, and Jessica Brand.

Microneedle Patch and Manufacturing Method

The USPTO has published a new patent application, US20260083949A1, filed by Gachon University of Industry-Academic Cooperation Foundation. The application discloses a microneedle patch designed to protect active pharmaceutical ingredients from moisture and contaminants.

Patent Application for Microstructure Array Delivering Active Agents

The USPTO has published a patent application (US20260083948A1) for a microstructure array designed for delivering active agents through the skin. The application details a formulation comprising dissolving microstructures attached to a base, intended for transdermal drug delivery.

Medical System and Liquid Circulation System for Brain Treatment

The USPTO has published a patent application (US20260083947A1) for a medical system and liquid circulation system designed for brain treatment. The system aims to efficiently deliver liquid to the brain while managing intracranial pressure fluctuations by controlling injection and discharge periods.

Powder Sprayer Patent Application

The USPTO has published a patent application (US20260084168A1) for a powder sprayer. The application details a device with specific air and powder inlets, a confluence channel, and an on-off valve system. The filing date was February 24, 2022.

USPTO Patent Application for Electrospraying Applicator Cartridges

The USPTO has published a new patent application (US20260084167A1) filed by Octet Medical, Inc. The application details disposable cartridges for electrospraying applicators, systems, and methods thereof. This represents a new intellectual property filing in the medical device sector.

Capsule Inhaler Patent for Phosphodiesterase-4 Inhibitor

The USPTO has published a new patent application (US20260083711A1) for a capsule inhaler designed for administering phosphodiesterase-4 inhibitors. The patent, assigned to Chiesi Farmaceutici S.p.A., details a drug product comprising a single-dose dry powder inhalation device and a pharmaceutical composition for treating respiratory diseases.

Patent Application for Implantable Sensors and Shunting Systems

The USPTO has published a new patent application (US20260083946A1) for implantable sensors and shunting systems. The application details a system for shunting blood between heart atria and includes a sensor with an actuation element to reduce tissue ingrowth. The filing date was December 3, 2025.

Patent Application for Variable Orifice Flow Shunt Devices

The USPTO has published a patent application (US20260083945A1) for variable orifice flow shunt devices designed to reduce peak systolic pressure. The application details devices with check valves and adjustable orifices for percutaneous shunting from the superior vena cava to the right pulmonary artery.

Capsule Inhaler for Phosphodiesterase-4 Inhibitor Patent Application

The USPTO has published a patent application (US20260083924A1) for a capsule inhaler device designed for administering a phosphodiesterase-4 inhibitor. The application, filed by Chiesi Farmaceutici S.P.A., details a drug product comprising a single-dose dry powder inhalation device and a pharmaceutical composition for treating respiratory diseases.

USPTO Patent Application for Atomizing Body Assembly

The USPTO has published a patent application (US20260083922A1) for an atomizing body assembly and soft mist device with improved sealing performance. The application details an assembly including a T-shaped steel member, chip-mounting part, filter cartridge, and O-ring designed to enhance sealing. The filing date was October 31, 2022.

Patent Application for Hot Air Curing Adhesive Method

The USPTO has published a patent application (US20260083921A1) for a method of curing adhesive with hot air treatment during the assembly of glass syringes. The application, filed by ATS Corporation, details a process involving dispensing, arranging, radiation curing, and hot air heating steps.

Split-Luer Lock Connector Patent Application

The USPTO has published a new patent application, US20260083920A1, for a Split-Luer Lock Connector. The application, filed on September 8, 2025, describes a male Luer coupler designed to facilitate peripheral device coupling to a host device.

USPTO Patent Application for Medicine Injecting Needle Module

The USPTO has published a new patent application (US20260083919A1) for a medicine injecting needle module filed by AGNES MEDICAL CO.,LTD. The application details a needle module designed for efficient medicine delivery.

Tamper Resistant Syringe Assembly Patent Application

The USPTO has published a patent application (US20260083918A1) for a tamper-evident and tamper-resistant syringe assembly filed by Civica, Inc. The application describes devices and methods to prevent tampering with pre-filled syringes and provide evidence of attempted access.

Auto injector with reconstitution handling support patent

The USPTO has published a new patent application, US20260083917A1, for an auto-injector with reconstitution handling support. The patent describes a device designed to mix medicament components within the auto-injector before administration, with a processing unit controlling the mixing process and providing an onset signal.

Drug Delivery Device Assembly Patent Application

The USPTO has published a new patent application, US20260083916A1, detailing an assembly for a drug delivery device. The application, filed on December 1, 2025, describes a novel cap mechanism for drug reservoirs that converts rotational user input into axial movement for release.

Autoinjector Patent Application Details Injection Device

The USPTO has published a new patent application, US20260083915A1, detailing an autoinjector for the automatic injection of medical products. The application was filed on August 11, 2023, and describes specific mechanical components and their interactions for drug delivery.

Medicament Delivery Device Patent Application

The USPTO has published a new patent application, US20260083914A1, related to a medicament delivery device and its subassembly. The application was filed on August 29, 2023, by inventors Daniel Säll, Tai-Fu Wang, and Chun-Hsien Huang.

Patent Application: Remote-Controlled Rotating Hand Mechanism in Aesthetic Medicine

The USPTO has published a new patent application (US20260083913A1) for a remote-controlled rotating hand mechanism designed for aesthetic medicine procedures. The application details a system incorporating multiple motors, ultrasound technology for safety monitoring, and a software platform for enhanced user experience and training.

Infusion Pump System Connectivity Site Tracking Patent Application

The USPTO has published a new patent application (US20260083911A1) detailing methods and systems for establishing communication protocols between wireless devices in infusion pump systems. The application focuses on coordinating communications among components like infusion pumps, CGM systems, and smartphones to ensure reliable medical data transmission.

Insulin Dosing Function System Using Reinforcement Learning

The USPTO has published a patent application (US20260083909A1) detailing a system and method for calculating an insulin dosing function using reinforcement learning. The application describes a process that utilizes self-attention and a State-Action-Reward-Next State sequence to optimize insulin dosage decisions in automated medical systems.

New Mexico Measles Cases Rise to 15 Linked to Detention Centers

The New Mexico Department of Health reported that the state's measles case count has risen to 15, with all cases linked to federal detainees in three county detention centers. The department has deployed vaccination crews to these facilities to mitigate further spread.

Remarks on Nonbank Designation Proposal

SEC Chairman Paul S. Atkins made remarks supporting a proposal at the Financial Stability Oversight Council meeting on March 25, 2026. While supporting the proposal as a step in the right direction, he reiterated skepticism about the fundamental issues with nonbank designation under the Dodd-Frank Act.

PHMSA Compromise Order with Certificate of Service

The Pipeline and Hazardous Materials Safety Administration (PHMSA) has issued a Compromise Order and Certificate of Service related to case number 24-0240-SH-EA concerning FHS Retail LLC. This order signifies a resolution to a compliance matter involving hazardous materials transportation.

Maryland AG Statement on Meta and YouTube Verdicts Harming Children

Maryland Attorney General Anthony G. Brown issued a statement following landmark verdicts against Meta and YouTube for designing social media platforms that exploit children and harm their mental health. The verdicts are seen as a reckoning for an industry that prioritizes profit over young people's well-being, and Maryland is part of similar multistate litigation.

Maryland AG Seeks Records on Baltimore ICE Detention Facility Conditions

The Maryland Attorney General has filed a motion for summary judgment against U.S. Immigration and Customs Enforcement (ICE) and the Department of Homeland Security (DHS) to compel the production of records concerning alleged dangerous and inhumane conditions at the Baltimore ICE detention facility. The lawsuit stems from an investigation into potential civil rights violations.

DEA Classifies Bromazolam as Schedule I Controlled Substance

The U.S. Drug Enforcement Administration (DEA) has classified bromazolam, a designer benzodiazepine, as a Schedule I controlled substance nationwide. This action, requested by a coalition of state attorneys general, aligns bromazolam with substances like heroin and LSD and empowers law enforcement to address its distribution.