Patent Application for Novel Crystalline Form of Amine Compound
Summary
The USPTO has published a patent application (US20260085071A1) for novel crystalline forms of an amine compound, 1-(8-bromopyrido[2,3-e][1,2,4]triazolo[4,3-a]pyrazin-4-yl)-N-methylazetidin-3-amine. The application also discloses pharmaceutical compositions and the use of these forms for treating diseases such as atopic dermatitis and urticaria.
What changed
This document is a published patent application from the USPTO detailing novel crystalline forms of a specific amine compound, identified as 1-(8-bromopyrido[2,3-e][1,2,4]triazolo[4,3-a]pyrazin-4-yl)-N-methylazetidin-3-amine. The application, filed on September 29, 2023, and published as US20260085071A1, includes claims for pharmaceutical compositions containing these crystalline forms and their use in treating various dermatological conditions, including atopic dermatitis, itch, pruritus, and urticaria.
While this is a patent application and not a regulatory rule, it signifies potential new intellectual property in the pharmaceutical space. Companies involved in drug development, particularly for dermatological conditions, should be aware of this filing as it may impact future research, development, and market exclusivity for similar compounds. No immediate compliance actions are required for entities outside of those directly involved in the patent process or those whose existing intellectual property might be affected.
Source document (simplified)
NOVEL CRYSTALLINE FORM OF 1-(8-BROMOPYRIDO[2,3- E][1,2,4]TRIAZOLO[4,3-A]PYRAZIN-4-YL)-NMETHYLAZETIDIN- 3-AMINE
Application US20260085071A1 Kind: A1 Mar 26, 2026
Inventors
Suha PARK, Seiho CHIN, Sumin LEE
Abstract
Novel crystalline forms of 1-(8-bromopyrido[2,3-e][1,2,4]triazolo[4,3-a]pyrazin-4-yl)-N-methylazetidin-3-amine is provided along with pharmaceutical compositions comprising the same. Also disclosed is the use of the novel polymorph for the treatment of diseases, such as atopic dermatitis (AD), itch, pruritus and various forms of urticaria for example chronic idiopathic urticaria subtypes.
CPC Classifications
C07D 471/14 A61K 31/4985
Filing Date
2023-09-29
Application No.
19110267
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