Changeflow GovPing Pharma & Drug Safety Protein Degraders Patent Application
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Protein Degraders Patent Application

Favicon for changeflow.com ChangeBridge: Patent Apps - Organic Chemistry (C07D)
Published August 19th, 2025
Detected March 26th, 2026
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Summary

The USPTO has published a new patent application, US20260085075A1, related to protein degraders and their uses. The application was filed on August 19, 2025, by inventors Nello Mainolfi, Nan Ji, Yi Zhang, and Matthew M. Weiss.

What changed

The United States Patent and Trademark Office (USPTO) has published a new patent application, US20260085075A1, concerning protein degraders and methods for their use in treating protein-mediated disorders. The application, filed on August 19, 2025, by inventors Nello Mainolfi, Nan Ji, Yi Zhang, and Matthew M. Weiss, includes abstract claims for compounds and compositions designed for targeted protein degradation.

This publication represents a new patent application filing and does not impose immediate compliance obligations. However, it signifies potential future intellectual property developments in the field of targeted protein degradation, which may impact research and development strategies for pharmaceutical and biotechnology companies. Companies operating in this space should monitor the progress of this application and related patents.

Source document (simplified)

← USPTO Patent Applications

PROTEIN DEGRADERS AND USES THEREOF

Application US20260085075A1 Kind: A1 Mar 26, 2026

Inventors

Nello Mainolfi, Nan Ji, Yi Zhang, Matthew M. Weiss

Abstract

The present invention provides compounds, compositions thereof, and methods of using the same for the targeted degradation of proteins, and the treatment of target protein-mediated disorders.

CPC Classifications

C07D 495/14

Filing Date

2025-08-19

Application No.

19304052

View original document →

Named provisions

Abstract

Classification

Agency
USPTO
Published
August 19th, 2025
Instrument
Notice
Legal weight
Non-binding
Stage
Draft
Change scope
Minor
Document ID
US20260085075A1
Docket
19304052

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Drug Discovery Intellectual Property Management
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Topics
Intellectual Property Biotechnology

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