Viscoelastic Hydrogel Regulates Organoid Patterning and Vascularization

The USPTO has published a new patent application, US20260086082A1, detailing a viscoelastic hydrogel for regulating organoid patterning and vascularization. The application, filed by inventors Changchun Zeng, Yan Li, and Xingchi Chen, focuses on a spinal cord model.

Viscoelastic Hydrogel Regulates Organoid Patterning and Vascularization

The USPTO has published a new patent application, US20260086081A1, detailing a viscoelastic hydrogel for regulating organoid patterning and vascularization. The application, filed on April 10, 2025, describes spinal cord models using methacrylated hyaluronic acid and dopamine-modified hyaluronic acid.

Ovarian and Uterine Organoid Production and Pharmaceutical Screening

The USPTO has published a patent application detailing methods for producing ovarian and uterine organoids from stem cells. These organoids are intended for use in screening pharmaceutical interventions for diseases and for applications in hormone replacement therapy and assisted reproduction technologies.

Enzyme-containing article with water barrier properties

The USPTO has published a new patent application, US20260085163A1, detailing an enzyme-containing biodegradable single-layer article with water barrier properties. The application was filed by Vincent Legrand and includes various CPC classifications related to polymers and enzymes.

Patent Application: Method of Differentiating Pluripotent Stem Cells to Hematopoietic Cells

The USPTO has published a patent application (US20260085288A1) detailing a method for differentiating pluripotent stem cells into hematopoietic precursor and stem cells. The application, filed by Boris Greber and Daniel Terheyden-Keighley, outlines a process using specific induction cocktails for generating immune cells like NK cells.

Therapeutic Macrophages Patent Application

The USPTO has published a patent application (US20260085287A1) filed by Resolution Therapeutics Limited for therapeutic macrophages genetically engineered to overexpress Interleukin-10 (IL-10) or IL-10 in combination with Matrix Metallopeptidase 9 (MMP9). This application relates to potential treatments for inflammatory conditions.

Anti-tumor immune response enhancer patent application

The USPTO has published a new patent application, US20260085286A1, detailing an 'Anti-tumor immune response enhancer'. The application, filed by Kenichiro Hasumi, describes a composition comprising phospholipids to enhance anti-tumor activity and induce cytokine production.

Methods for Producing Retinal Pigment Epithelium Cells

The USPTO has published a new patent application detailing methods for producing retinal pigment epithelium (RPE) cells. The application describes specific culturing and replating techniques using laminin substrates to expand and mature RPE cells for potential therapeutic uses.

Method for Trans-Differentiating Non-Neuronal Cells into Neurons

The USPTO has published a patent application (US20260085284A1) from SHANGHAI GENEMAGIC BIOSCIENCES CO., LTD. for a method of trans-differentiating non-neuronal cells into neurons using specific regulators. The application was filed on August 30, 2023.

Stem cell-derived gastruloid model and construction method

The USPTO has published a patent application detailing a stem cell-derived gastruloid model and its construction method. This model simulates early embryonic development and can be used for drug screening and safety testing, particularly for early pregnancy applications.