USPTO Patent Grant: Peptides for Treating Glioma Tumors

The USPTO has granted patent US12582695B2 for peptides, compositions, and methods to treat glioma tumors infiltrated with macrophages. The patent was filed on November 27, 2019, and is assigned to Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polska Akademia Nauk.

Patent for Crohn's Disease Indicator and Treatment

The USPTO has granted Washington University a patent (US12582696B2) for methods to treat, select, and monitor inflammatory bowel disease using Debaryomyces species as a biomarker. The treatment involves administering an antifungal compound and detecting fungal DNA or antibodies.

USPTO Patent Grant: Botulinum Toxin for Infertility Treatment

The USPTO has granted a patent (US12582705B2) to CHA UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION for a composition comprising botulinum toxin or a salt thereof. This composition is intended to increase endometrial blood flow and improve implantation potential, potentially treating subfertility or infertility.

USPTO Grants Patent for Glutathione Trisulfide in Neuroprotection

The USPTO has granted a patent (US12582693B2) to The General Hospital Corporation for methods using glutathione trisulfide (GSSSG) in neuroprotection. The patent covers uses in treating neurodegenerative diseases and reducing ischemic injury risk.

USPTO Patent Grant: Tumor Treatment with Antibodies

The USPTO has granted patent US12582713B2 to Bristol-Myers Squibb Company for methods of treating tumors using pharmaceutical compositions containing anti-PD-1 or anti-PD-L1 antibodies, particularly for subcutaneous delivery. The patent also covers compositions that include an endoglycosidase hydrolase enzyme.

USPTO Patent Grant: Immunopotentiating Amino Acid Mineral Complex

The USPTO has granted a patent (US12583873B2) to BTN CO., LTD. for an amino acid mineral complex with immunopotentiating activity. This complex can be used in compositions for foods, pharmaceuticals, or feeds to enhance immunity or antibody production in humans and animals.

USPTO Patent Granted for Cognitive Disorder Treatment Compound

The USPTO has granted patent US12583884B2 to AELIS FARMA for a compound, 3beta-(benzyloxy)-17alpha-methyl-pregn-5-en-20-one, for use in treating cognitive disorders. The patent filing date was December 18, 2019.

USPTO Grants Patent for Flavivirus Cross Neutralizing Antibody

The USPTO has granted patent US12583912B2 for a flavivirus cross-neutralizing antibody developed by the Japan Institute for Health Security. This antibody specifically targets the E protein of flaviviruses, including Zika, dengue, and Japanese encephalitis viruses, and aims to control infection with suppressed Antibody-Dependent Enhancement (ADE).

USPTO Patent for Alzheimer's Treatment Using LRP1/SorLA Antagonist

The USPTO has granted a patent (US12583920B2) to the University of Maryland, Baltimore, for methods and compositions to treat or prevent Alzheimer's disease using LRP1 and/or SorLA antagonists. The patent covers specific therapeutic approaches targeting tau internalization and trafficking in neuronal cells.

USPTO Patent Grant: ARDS Treatment with G-CSF Inhibitors

The USPTO has granted patent US12583929B2 to CSL Innovation Pty Ltd for methods of treating acute respiratory distress syndrome (ARDS) using compounds that inhibit G-CSF signaling. The patent covers compounds and their use in manufacturing medicaments for ARDS prevention and treatment.

USPTO Patent Grant for GIP Receptor Antibodies

The USPTO has granted patent US12583930B2 to Crystal Bioscience Inc. for GIP receptor antibodies designed to treat metabolic disorders, specifically those related to glucose metabolism. The patent covers antibodies that bind to and inhibit the human glucose-dependent insulinotropic polypeptide (GIP) receptor.

USPTO Grants Patent for Benzothiazole Compound for Parkinson's and Restless Leg Syndrome

The USPTO has granted a patent (US12583829B2) to Sichuan Kelun Pharmaceutical Research Institute Co., Ltd. for a salt of a benzothiazole compound and its crystal form. The patent covers the use of this compound in the preparation of drugs for treating Parkinson's disease and restless leg syndrome.

USPTO Patent Grant for Viral Infection Compounds Targeting Sigma Receptors

The USPTO has granted a patent (US12582619B2) to Thomas Jefferson University for compounds that modulate Sigma receptors to treat viral infections. The patent covers methods for preventing, treating, or ameliorating viral infections using these compounds, potentially in combination with other therapeutic agents.

USPTO Grants Patent for Sodium Oxybate to Treat Idiopathic Hypersomnia

The United States Patent and Trademark Office (USPTO) has granted patent US12582622B2 to Jazz Pharmaceuticals Ireland Limited for methods of treating idiopathic hypersomnia with sodium oxybate. The patent is effective March 24, 2026.

Vineet Bhardwaj vs Registrar Cooperative Society - Membership Dispute

The Delhi High Court heard a case concerning a dispute over membership allotment in a cooperative housing society. The court is reviewing the Registrar of Cooperative Societies' refusal to approve the petitioner's membership, citing a violation of Rule 19(2) of the Delhi Cooperative Society Rules, 2007.

Orissa Alloy Steel Private Limited vs Union Of India & Ors - Land Compensation Dispute

The Delhi High Court is hearing a petition from Orissa Alloy Steel Private Limited seeking compensation for 1230.58 acres of land. The petitioner claims title to the land parcels acquired through a liquidation process and disputes the Final Compensation Order dated February 22, 2022, which granted compensation to Essar Power Limited.

Kusmode vs Union of India - Notary Public Certificate Cancellation

The Delhi High Court has ruled on a petition concerning the cancellation of a Notary Public's Certificate of Practice. The court reviewed an inquiry report and order that led to the removal of the petitioner's name from the Register of Notaries. The decision addresses the restoration of the petitioner's certificate and his ability to continue practicing.

Rohit Kumar v. Sukhdev Singh & Ors - Motor Accident Compensation Appeal

The Delhi High Court heard an appeal seeking enhancement of compensation awarded by the Motor Accidents Claims Tribunal. The appellant, who suffered grievous injuries in a 2012 road accident, sought increased compensation based on functional disability, future prospects, and non-pecuniary damages.

Wadia Techno Engineering Services vs Director General Married Accommodation Project - Appeal

The Delhi High Court has issued a judgment in the case of Wadia Techno Engineering Services Limited vs. Director General of Married Accommodation Project. The judgment was reserved on February 3, 2026, and pronounced on March 24, 2026. This case involves appeals related to commercial matters.

IPL Sugars vs S.B. Bhad - Recovery Suit

The Delhi High Court issued a decision in a recovery suit filed by IPL Sugars & Allied Industries Ltd. against S.B. Bhad. The suit seeks recovery of Rs. 30,68,92,600/- along with interest. The court's decision details the background of the case, including the plaintiff's business and the contract for a sugar plant project.

Dr. Adla Satya Narayan Rao v. Union Of India And Anr - RTI Act Challenge

The Delhi High Court has issued a decision in a case challenging orders related to an application filed under the Right to Information Act. The petitioner sought information regarding market authorization for a pharmaceutical product, which was initially rejected by the CPIO and subsequent appellate authorities.

Kanishka Sabharwal vs Suresh Kumar - Delhi High Court

The Delhi High Court has issued a judgment in the case of Kanishka Sabharwal vs. Suresh Kumar (since deceased). The court rejected the Appellant's suit for Declaration, Recovery of Possession, Mesne Profits, and Permanent Injunction, upholding the order of the District Judge.

Nisha Chandola vs Manoj Sharma - Perjury Proceedings

The Delhi High Court is considering initiating perjury proceedings against Defendant No. 1 in the case of Nisha Chandola & Anr vs Manoj Sharma And Anr. The application seeks to prosecute the defendant for allegedly making false statements on oath in court pleadings and affidavits related to a partition suit.

Yasiv Zaidi v. Man Mohan Arora - Negotiable Instruments Act Case

The Delhi High Court has issued a judgment in the case of Yasiv Zaidi vs. Man Mohan Arora concerning a complaint filed under Section 138 of the Negotiable Instruments Act, 1881. The judgment addresses the petitioner's challenge to a prior decision by the Sessions Court, which had upheld an order from the Trial Court regarding a dishonored cheque.

National Insurance vs Laxmi Bisht - Motor Accident Appeal

The Delhi High Court is hearing an appeal filed by the National Insurance Company against an award granting compensation of Rs. 48,96,000/- plus interest to the respondents in a motor accident case. The appeal challenges the Motor Accident Claims Tribunal's decision, citing lack of concrete proof of negligence.

Thermoking vs Rashtriya Gen.Maz.Union - Delhi High Court Case

The Delhi High Court has issued a judgment in the case of M/s. Thermoking vs. P.O. & Rashtriya Gen.Maz.Union. The court is reviewing a prior award from the Labour Court that found the termination of workmen's services to be illegal and ordered their reinstatement with back wages.

Sheetal Yadav vs Swapnil Yadav - Civil Suit Rejection Application

The Delhi High Court is considering an application by Defendants No. 1 & 2 to reject a civil suit filed by Sheetal Yadav concerning partition, injunctions, and accounting for immovable properties. The defendants argue the suit is not maintainable as it is barred by law and lacks a cause of action.

Navdeep @ Sonu vs State - Delhi High Court Judgment

The Delhi High Court has issued a judgment in the case of Navdeep @ Sonu vs State (NCT of Delhi), concerning appeals against a conviction and sentence for offenses under Section 377 read with Section 34 of the Indian Penal Code and Section 6 of the Protection of Children from Sexual Offences Act, 2012. The judgment addresses appeals filed under Section 415(2) of the Bharatiya Nagarik Suraksha Sanhita, 2023.

Dr Rita Bakshi vs Seema Bajaj - Delhi High Court Judgment

The Delhi High Court has issued a judgment in the case of Dr Rita Bakshi vs Seema Bajaj. The case concerns the interpretation of Section 223 of the Bharatiya Nagarik Suraksha Sanhita, 2023 (BNSS), specifically the new proviso requiring an opportunity to be heard before cognizance is taken on a complaint. The judgment was uploaded on March 24, 2026.

Lalu Prasad Yadav v. Central Bureau Of Investigation - Criminal Petition

The Delhi High Court has issued a judgment in the case of Lalu Prasad Yadav vs. Central Bureau of Investigation. The petition sought to quash an FIR, charge sheets, and cognizance orders related to alleged irregular appointments in Group-D posts in various Zonal Railways between 2004-2009. The judgment was pronounced on March 24, 2026.

Sandeep Bedwal vs State - Delhi High Court Judgment

The Delhi High Court has issued a judgment in the case of Sandeep Bedwal vs State, concerning appeals against convictions for offenses under Sections 363 and 366 of the Indian Penal Code. The judgment, dated March 24, 2026, addresses appeals filed under Section 374 of the Code of Criminal Procedure.

Ramasethu Infrastructure v. Indian Railway Walfare Organisation - Contract Dispute

The Delhi High Court has issued a judgment in the case of Ramasethu Infrastructure vs. Indian Railway Walfare Organisation. The case involves a challenge to an arbitral award dated December 23, 2014, concerning a construction contract for dwelling units. The judgment was issued on March 24, 2026.

National Highways Authority vs Bel-Acc(Jv) - Arbitration Award Challenge

The Delhi High Court has issued a decision in the case of National Highways Authority of India vs. M/S Bel-Acc(JV). The petition challenges an arbitral award dated May 27, 2010, concerning a contract for highway construction. The court's decision will determine the outcome of this arbitration dispute.

Rohan Book Company Private Limited vs Sachin Tyagi - Defamation Suit Appeal

The Delhi High Court has condoned a delay of 132 days in filing an appeal by Rohan Book Company Private Limited against a lower court's order. The original suit sought damages for defamation but was rejected under Order VII Rule 11(a) of the CPC for not disclosing a cause of action.

Environmental Specialist Job Opening - Iowa DNR

The Iowa Department of Natural Resources is hiring an Environmental Compliance Specialist. The position involves assisting and directing regulated facilities in southwest Iowa to comply with environmental regulations. Applications are open to college students graduating in May 2026 with a Bachelor's Degree in a natural science.

Pastor Sentenced for Sex Crimes

Kentucky Attorney General Russell Coleman announced that former pastor Zachary King was sentenced to 13 years in prison for sex crimes against a minor church member. King pleaded guilty to seven felony counts and must register as a lifetime sex offender.

David Cox Sentenced for Threatening Judge

Kentucky Attorney General Russell Coleman announced that David Cox was sentenced to two years in prison for threatening a McCracken County District Judge. Cox pleaded guilty to intimidating a participant in the legal process and menacing. The sentence includes restrictions on contact with the judge and courthouse.

MDEQ Lifts Pass Christian West Beach Water Advisory

The Mississippi Department of Environmental Quality has lifted the beach water contact advisory for Pass Christian West Beach after water samples showed acceptable bacteria levels. This action removes a previous advisory, though a standing recommendation for swimming not to occur during or within 24 hours of significant rainfall remains.

Superior Court Vacates Termination, Remands for Counsel

The Pennsylvania Superior Court vacated an order terminating parental rights and remanded the case for a new hearing. The court found that the minor child was not represented by counsel, which is required by statute. The case involves a father appealing the termination of his parental rights to his child.

Custody Order Affirmed for Father in Roy v. Cianciotta

The Pennsylvania Superior Court affirmed a custody order that awarded sole legal and primary physical custody of one child to the mother and shared legal and primary physical custody of another child to the mother. The father had appealed the order, citing the parents' history of opioid addiction and criminal behavior.

T.M.G. v. O.T.C. - Parental Rights Termination Appeal

The Superior Court of Pennsylvania affirmed decrees terminating the parental rights of T.M.G. to her four children. The court granted the mother's counsel's application to withdraw, finding no reversible error in the lower court's decision.

Superior Court upholds denial of PCRA petition for ineffective counsel

The Pennsylvania Superior Court has upheld the denial of a PCRA petition filed by Jacob Tyler Rupert. Rupert had claimed ineffective assistance of trial counsel. The court affirmed the lower court's decision, finding no merit in the claims presented.

Kitner's Lawn & Landscaping, LLC v. LRM Masonry, LLC - Denial of Petition to Open Judgment

The Pennsylvania Superior Court affirmed the denial of a petition to open a default judgment against LRM Masonry, LLC. The court found that LRM failed to establish a reasonable excuse for not filing a timely answer and that the plaintiff complied with service requirements.

Custody Ruling Affirmed, Appeal Dismissed Due to Brief Defects

The Pennsylvania Superior Court affirmed a lower court's custody order and dismissed an appeal filed by the father due to defects in his appellate brief. The court cited the father's history of filing numerous motions and the specific deficiencies in the brief as grounds for dismissal.

Com. v. Snyder, C. - Affirmation of Motion to Suppress Denial

The Superior Court of Pennsylvania affirmed the denial of Corey Eugene Snyder's motion to suppress evidence. Snyder appealed his convictions for firearms offenses, arguing that evidence obtained during a parole search was improperly seized. The court found the search was conducted with reasonable suspicion as per the parole rules.

Weatherholtz v. McKelvey - Protective Order Ruling

The Pennsylvania Superior Court affirmed a protective order against Dylan Jacob McKelvey in the case of Weatherholtz v. McKelvey. The ruling stems from a second petition for a protective order filed by Kristin Allyn Weatherholtz following an encounter at a flea market. The court addressed the statute of limitations defense raised by the appellant.

Com. v. McElroy, J. - Appeal Dismissed

The Pennsylvania Superior Court has dismissed the appeal of Jody C. McElroy in docket number 616 MDA 2025. The appeal stemmed from the revocation of McElroy's probation following violations related to absconding from supervision. The court affirmed the judgment of sentence.

Com. v. Whitcomb, W. - Sentence Appeal Affirmed

The Pennsylvania Superior Court affirmed the judgment of sentence for William L. Whitcomb, who appealed his sentence following a guilty plea to involuntary deviate sexual intercourse with a child. The court found no basis for appeal and affirmed the lower court's decision.

Com. v. Gonzalez, J. - Affirmation of Sentence for Attempted Homicide and Assault

The Pennsylvania Superior Court affirmed the sentences for Julio Gonzalez, who was convicted of attempted homicide, assault, and discharging a firearm into an occupied structure. The court upheld the aggregate sentence of 29 to 67 years of incarceration.

CNCS Seeks Feedback on Service Delivery Collection

The Corporation for National and Community Service (CNCS) is seeking public feedback on a generic clearance for collecting qualitative feedback on its service delivery. This notice initiates a comment period for interested parties to provide input on the proposed data collection activities.