USPTO Grants Patent for Glutathione Trisulfide in Neuroprotection
Summary
The USPTO has granted a patent (US12582693B2) to The General Hospital Corporation for methods using glutathione trisulfide (GSSSG) in neuroprotection. The patent covers uses in treating neurodegenerative diseases and reducing ischemic injury risk.
What changed
The United States Patent and Trademark Office (USPTO) has granted patent US12582693B2 for methods involving the use of glutathione trisulfide (GSSSG) in neuroprotection. The patent, assigned to The General Hospital Corporation, specifically details applications for treating neurodegenerative diseases and mitigating the risk of ischemic injury to the brain, spinal cord, and peripheral nerves. The invention pertains to conditions that compromise blood flow and oxygen delivery, such as those resulting from surgery or trauma.
This patent grant signifies a new intellectual property right for a specific therapeutic method. While not a regulatory rule imposing obligations on other entities, it establishes exclusive rights for the assignee. Companies operating in the pharmaceutical or biotechnology sectors, particularly those involved in neurological treatments or therapies for stroke and trauma, should be aware of this granted patent to avoid potential infringement. No immediate compliance actions are required for external parties, but it impacts the competitive landscape for developing similar treatments.
Archived snapshot
Mar 24, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Glutathione trisulfide (GSSSG) in neuroprotection
Grant US12582693B2 Kind: B2 Mar 24, 2026
Assignee
The General Hospital Corporation
Inventors
Fumito Ichinose, Eizo Marutani
Abstract
Methods for the use of glutathione trisulfide (GSSSG) in neuroprotection, e.g., in neurodegenerative diseases and to reduce the risk of ischemic injury. The methods can be used, e.g., to reduce risk of injury to brain, spinal cord, and peripheral nerves from ischemia or low blood flow states possibly caused by surgery, trauma, and other conditions that decrease/impair blood flow and or oxygen delivery to the nervous system.
CPC Classifications
A61K 38/063 A61K 9/0019 A61K 9/08 A61K 47/20 A61P 25/00 A61P 25/28 C07K 5/0215 C07K 5/0606 C07K 5/0819
Filing Date
2021-05-11
Application No.
17924622
Claims
5
Named provisions
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Source
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