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USPTO Patent Grant: ARDS Treatment with G-CSF Inhibitors

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Published March 24th, 2026
Detected March 24th, 2026
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Summary

The USPTO has granted patent US12583929B2 to CSL Innovation Pty Ltd for methods of treating acute respiratory distress syndrome (ARDS) using compounds that inhibit G-CSF signaling. The patent covers compounds and their use in manufacturing medicaments for ARDS prevention and treatment.

What changed

The United States Patent and Trademark Office (USPTO) has issued patent US12583929B2, granting CSL Innovation Pty Ltd exclusive rights to methods of treating or preventing acute respiratory distress syndrome (ARDS) through the use of G-CSF signaling inhibitor compounds. The patent also covers the compounds themselves and their application in the manufacture of medicaments for ARDS.

This patent grant signifies a new intellectual property right in the therapeutic area of ARDS. While not a regulatory rule imposing obligations on other entities, it establishes exclusive rights for the assignee, potentially impacting future research, development, and commercialization efforts by other pharmaceutical companies in this specific treatment area. Compliance officers in the pharmaceutical sector should be aware of this patent if their organization is involved in ARDS research or development.

Source document (simplified)

← USPTO Patent Grants

Method of treating acute respiratory distress syndrome

Grant US12583929B2 Kind: B2 Mar 24, 2026

Assignee

CSL Innovation Pty Ltd

Inventors

Adriana Baz Morelli, Ian Keith Campbell, Karolina Krstevski

Abstract

The present disclosure relates to methods of treating or preventing acute respiratory distress syndrome (ARDS) using compounds that inhibit G-CSF signaling. The present disclosure also relates to compounds for use in the treatment or prevention of ARDS, as well as the use of such compounds in the manufacture of medicaments for the treatment or prevention of ARDS.

CPC Classifications

C07K 16/2866 C07K 2317/76 A61P 11/00

Filing Date

2021-06-07

Application No.

18000153

Claims

17

View original document →

Named provisions

Method of treating acute respiratory distress syndrome

Classification

Agency
USPTO
Published
March 24th, 2026
Instrument
Rule
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12583929B2

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Development Drug Labeling
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Compliance frameworks
GxP
Topics
Intellectual Property Medical Research

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