Catheter Pump Flexible Shaft Core Patent Application, ECP Entwicklungsgesellschaft

USPTO published patent application US20260110327A1 filed by ECP Entwicklungsgesellschaft mbH on May 5, 2025, covering a catheter pump flexible shaft arrangement with a reinforced core extending through the interior of a flexible hollow shaft. The invention enables selective positioning of stiffer and more flexible sections within the shaft to optimize performance. CPC classifications include A61M 60/135, A61M 60/216, A61M 60/408, A61M 60/414, and related mechanical categories.

Breastfeeding System Patent US20260108292A1

The USPTO published patent application US20260108292A1 for a breastfeeding system, filed October 14, 2025, by inventor Alan N. Schwartz. The application describes a breastfeeding collection and simulation device featuring conformable breast cover layers with receptacle spaces for liquid collection, combined with simulation devices that mimic breastfeeding interactions. The invention falls under CPC classifications A61M and related medical device categories.

Liquid Applicator for Delivering Vaccines

USPTO published patent application US20260108340A1 (filed November 12, 2025, Application No. 19386697) for a liquid applicator device designed to administer liquids, including vaccines, to animals via mouth delivery. The application names three inventors: Aurelie de Malibran-Santibanez, Alonso Prado-Masias, and Frederic David. CPC classifications span veterinary instruments, pharmaceutical packaging, and medical delivery device categories.

Biopsy Marker Deployment Device - Bard Peripheral Vascular

Bard Peripheral Vascular, Inc. has published patent application US20260108321A1 for a biopsy marker deployment device. The device comprises a deployment catheter with a cutting tip, a first lumen with a distal opening, a second lumen shaped to hold multiple markers, and two push rods that independently advance markers from the second lumen through the first lumen and out the distal opening. The application was filed on September 29, 2022, under application number 19115459. This published application makes the technical details of the invention publicly available for examination.

Enteral Feeding Bag and Pump Support, US Patent Application A1, Apr 23, 2026

USPTO published patent application US20260108429A1 for an enteral feeding bag support system filed September 17, 2025 by inventors Benjamin Harris, Joel Wiesner, Jeffrey Markwardt, Wayne Biermann, and Kenneth Breitweiser. The system comprises a base with a support portion and attachment portion for removably attaching a medical device, and a pole assembly attachable to the base that suspends the medical bag above the support surface. Healthcare facilities and medical device manufacturers should monitor issued patents in this space for freedom-to-operate and licensing considerations.

Compositions, Devices, and Methods for Intranasal Delivery of Dry Powder Epinephrine

Belhaven BioPharma Inc. has filed USPTO patent application US20260108459A1 for intranasal dry powder epinephrine compositions. The application was filed on June 19, 2025, with inventors Scott Lyman and Brian Taubenheim. The compositions include epinephrine with citric acid as a stabilizing agent and are intended for treating anaphylaxis, bronchospasms, respiratory impairment, organophosphate poisoning, and major adverse cardiac events.

LivaNova Roller Pump, Adjustable Rollers, Perfusion System

LivaNova Deutschland GmbH has filed USPTO patent application US20260110295A1 for a roller pump with electronically adjustable roller positions for use in extracorporeal perfusion systems. The invention includes a rotor with first and second roller arms, each having rollers rotatably coupled, a raceway disposed around the rotor, and an electronic actuator configured to change the radial position of the rollers. An extracorporeal perfusion system incorporating this pump would include a fluid reservoir, oxygenator, and flexible tubing disposed within the raceway, with the motor configured to rotate the rotor to cause fluid flow within the tubing.

GIP Receptor Agonist Compounds for Diabetes, Obesity

The USPTO published patent application US20260108546A1 on April 23, 2026, covering GIP (Glucose-dependent Insulinotropic Polypeptide) receptor agonist compounds and their pharmaceutical compositions for the treatment of type II diabetes mellitus and obesity. The application, filed June 17, 2025, names 18 inventors and includes detailed CPC classifications spanning pharmaceutical chemistry, heterocyclic compounds, and organophosphorus compounds. This publication establishes a priority date and makes the claims publicly available for prior art review by competitors and researchers in the metabolic therapeutics space.

Syqe Medical Ltd. THC Inhaler, 0.75mg Max

Syqe Medical Ltd. filed patent application US20260108542A1 on December 19, 2025 (application no. 19426146), published April 23, 2026, covering a THC inhaler system with a scheduled regimen that caps delivery at 0.75 mg THC or less over a minimum 2-hour period. The system includes a memory storing the regimen, a decision module that determines whether delivery should occur, and a controller in the inhaler device executing delivery based on those decisions. The named inventors include Perry Davidson, Seth Kindler, Shlomo Almog, Binyamin Schwartz, Aaron Schorr, and Daniella Atzmony.

Paeoniflorin-Isoliquiritigenin Composition Treats Pulmonary Fibrosis

The USPTO has published patent application US20260108548A1, assigned to Henan University of Chinese Medicine, covering a therapeutic composition of paeoniflorin and isoliquiritigenin for treating diffuse interstitial pulmonary fibrosis. The application was filed on October 8, 2023 (Application No. 19129203) and names nine inventors including Jiansheng Li and Peng Zhao. The composition is claimed to provide anti-inflammatory, antioxidant, and collagen deposition inhibition effects. Patent applications are informational publications — no examination or grant decision has been made.

Self-Emulsifying Cannabinoid Tablet Formulations by Fertin Pharma

Fertin Pharma A/S has filed USPTO Application US20260108543A1 for an orally dissolvable or chewable tableted powder formulation incorporating self-emulsifying systems loaded with at least 10% cannabinoids by weight. The formulation includes 20-80% water-soluble agents by weight, one or more flavors, and surfactants containing polyethylene glycol moieties. The application covers both liquid self-emulsifying systems (with surfactants, lipids, and isolated or synthetic cannabinoids) and solid self-emulsifying systems (with surfactants, waxes, and isolated or synthetic cannabinoids). Filing date was December 22, 2025.

L-fucose Treats Infectious Diseases and Cancers - US20260108547A1

The USPTO has published patent application US20260108547A1, filed on October 4, 2023, disclosing methods for treating infectious diseases and cancers by administering L-fucose to a subject. The application names Eric LE-LAU as inventor and claims therapeutic uses of the monosaccharide L-fucose in medical treatments. This patent publication establishes prior art and may affect freedom-to-operate analyses for competing therapeutics developers.

Tryptamine Compositions for Enhancing Neurite Outgrowth

US Patent Application US20260108544A1, filed February 7, 2025 and published April 23, 2026, covers neurotrophic and nootropic compositions comprising tryptamines from psilocybin-containing mushrooms, optionally combined with phenethylamines, amphetamines, erinacines, hericenones, and cannabinoids. The application names Paul Edward Stamets as inventor and lists multiple CPC classifications spanning pharmaceutical chemistry and botanical extracts. This publication makes the application publicly available for review and potential opposition prior to grant.

Novel Liquid Oral CBD Formulations, Published Apr 23

The USPTO published patent application US20260108540A1 on April 23, 2026, covering stable liquid oral pharmaceutical formulations of synthetic Cannabidiol (CBD). The application, filed June 24, 2023 (Application No. 19120456), names inventors Chandrashekhar KOCHERLAKOTA and Srinivas ARUTLA. The formulations comprise synthetic CBD combined with pharmaceutical excipients including solvents, oils, organoleptic modifiers, buffers, and surfactants.

Macrolide Compound Patent Application, Institute of Feed Research, Chinese Academy of Agricultural Science

The USPTO has published patent application US20260108549A1 for a macrolide compound, filed by the Institute of Feed Research under the Chinese Academy of Agricultural Sciences, with inventors Xiubo LI, Fei XU, Yiming LIU, and Xiaojie CHEN. The application, filed May 31, 2024, covers pharmaceutical and veterinary compositions containing the macrolide compound for treating pathogen infections, especially in animals. Patent applications are published to establish priority and allow public review of the invention.

Aminergic Phytocannabinoids Derivatives as Multi-Target Agents for Neurological Disorders

The University of South Carolina has filed patent application US20260108541A1 with the USPTO for aminergic phytocannabinoid derivatives as multi-target agents for treating neurological disorders in mammals including humans. The application covers CBD derivatives functionalized at position 7 and THC derivatives functionalized at position 11. Inventors are Juan Francisco Leon Oyola and Zachary I. Stryker.

Implantable Body Armor for Protecting Internal Organs

The USPTO published patent application US20260108342A1 by inventor Michel GAGNER on April 23, 2026, covering an implantable body armor device for protecting internal organs. The device includes a flexible panel composed of layers of woven fibers configured to absorb impact energy, and is operable between a delivery configuration and a functional configuration. Filing date was April 11, 2025, under application number 19176694. This publication does not grant patent rights; it makes the application available for public inspection.

AI Surgical Planning System for Heart Valve Repair

USPTO published patent application US20260108307A1 titled 'Generative Computational Predictive Model for Soft Tissue Repair Planning,' filed December 18, 2025 by inventors Taylor Nicole Becker, Lakshmi Prasad Dasi, and Shelley Chee-Mei Gooden. The application covers a computer-implemented method for receiving 3D imaging of a heart valve in a pre-operative state, generating a segmented heart valve, simulating a surgical procedure, and determining at least one post-operative outcome based on the simulation. This patent represents an advancement in AI-assisted surgical planning for cardiovascular procedures.

Bone Surface Registration Patent for Orthopedic Procedures

USPTO published patent application US20260108306A1 (Application No. 19423871) on April 23, 2026, disclosing systems and methods for negative registration of bone surfaces used in orthopedic procedures. The invention enables a computing device to project geometry data of a first bone-contacting surface into a second bone's coordinate space and map the projected geometry across multiple poses within a patient's range of motion to generate data indicative of the second bone-contacting surface. The patent lists Adam Ryals and Daniel Girardeau-Montaut as inventors.

T-Cell Modulatory Polypeptides and KRAS Peptide Cancer Treatment Methods

USPTO published patent application US20260109958A1 by inventors Chee Meng Low and Ahmet Selim Vakkasoglu on April 23, 2026, covering T-cell modulatory polypeptides (TMPs) comprising a KRAS peptide linked to class I MHC polypeptides, fusion molecules with heterologous partners, and single-chain immunomodulatory constructs with Ig Fc or non-Ig scaffolds. The application claims compositions and methods for modulating T-cell activity and treating KRAS-associated cancers including lung, colorectal, and pancreatic cancers. Filing date was December 16, 2025, under application number 19422115.

Particle-Based Separation of Extracellular Vesicles, University of Idaho, Apr 23, 2026

The University of Idaho has published patent application US20260109943A1, covering methods, compositions, and kits for isolating extracellular vesicles (EVs) using a chitin-based stationary phase material functionalized with a fusion protein comprising a lactadherin C1C2 domain, a chitin-binding domain (CBD), and an intein. The application, filed October 17, 2025, was published April 23, 2026. CPC classifications include C12N 5/04, C07K 14/46, and C07K 2319/00. Inventors are listed as Ching-An Peng.

Methods and Compositions for Hematopoietic Cell Differentiation

USPTO published application US20260109951A1 titled "Methods and Compositions for Inducing Hematopoietic Cell Differentiation," filed September 12, 2023. The application discloses culture platforms, cell media, and methods for differentiating pluripotent stem cells into hematopoietic lineage cells including T cell progenitors, NK cells, NKT cells, and B cells. Named inventors are Alec Witty, Amanda Yzaguirre, Jode Goodridge, Bahram Valamehr, Samuel Adam LaBarge, and Sean Sherman.

Universal Display Corp Organic Electroluminescent Compound Patent Application

Universal Display Corporation filed patent application US20260114182A1 on April 23, 2026, covering a compound of Formula I for organic electroluminescent materials and devices. The application claims compounds with a 5-membered or 6-membered aromatic ring, where at least one of X1 to X3 is nitrogen, with substituents including alkyl, cycloalkyl, aryl, heteroaryl groups, and optional partial or full deuteration. Named inventors are Peter Wolohan, Tyler Fleetham, Jason Brooks, Rasha Hamze, and Nicholas J. Thompson. CPC classifications include H10K 85/6572, C07D 403/14, C07D 487/04, C09K 11/06.

Organic Compound for Electroluminescent Devices, US20260114179A1

USPTO published patent application US20260114179A1 on April 23, 2026, covering an organic compound for electroluminescent devices with a structure shown in Formula 1. The application, filed April 12, 2024 under application number 19161669, names inventors Xianbin XU and Lei YANG. The CPC classifications include H10K 85/636, C07D 413/12, and C09K 11/02, indicating applications in organic electronics and semiconductor technology.

Novel OLED Compound With Rigid Fluorene Substituent - US20260114181A1

USPTO published patent application US20260114181A1 on April 23, 2026, covering a novel organic light-emitting compound where a rigid fluorene-based substituent is introduced into 1,10-phenanthroline. The application (No. 19359671) was filed on October 15, 2025, by inventors A Reum Lee, So Jeong Moon, Joo Hee Jang, Jae Duk Yoo, Young Jae Kwon, Da Young Park, and A Reum Hyun. The compound is designed for use in electron transport layers, hole blocking layers, and N-type charge generation layers of OLEDs to achieve low voltage operation, high efficiency, and extended device lifespan.

Missouri AG Forces Pressure STL to Cease Operations and Destroy Illegal THC Products

Missouri Attorney General Catherine Hanaway filed a lawsuit in February 2026 against Pressure STL, an unlicensed dispensary in St. Louis, alleging violations of Missouri's constitutional marijuana framework and the Missouri Merchandising Practices Act. After negotiations, Pressure STL agreed to an Assurance of Voluntary Compliance approved by the Circuit Court of the City of St. Louis, requiring immediate cessation of all business operations in Missouri and destruction of all psychoactive cannabinoid products that deceptively mimicked children's candy and snacks. The AG's office warns Missourians against purchasing THC products from unlicensed dispensaries, citing FDA's position that no intoxicating hemp products have been approved for safe use.

CJEU Upholds Annulment of Lufthansa €6B COVID-19 Recapitalization State Aid Decision

The Court of Justice dismissed Lufthansa's appeal and upheld the General Court's May 2023 ruling that annulled the European Commission's June 2020 decision approving Germany's €6 billion recapitalization of Lufthansa during the COVID-19 pandemic. The CJEU found that the Commission infringed the Temporary Framework for State aid by accepting flawed methods for determining share price at the conversion of Silent Participation II into equity. The General Court was wrong on several other grounds where it had carried out an overly strict examination of the Commission's broad discretion in complex economic contexts. The Commission's decision is now annulled, meaning the approval of the €6 billion aid measure has been invalidated.

EU Court Bars Interest on Credit Insurance Costs

The CJEU held in Case C-744/24 that banks may not charge interest on sums used to pay credit insurance costs associated with consumer loans. The Court ruled that the 'total amount of credit' and 'total cost of the credit to the consumer' are mutually exclusive concepts under Directive 2008/48/EC, meaning insurance premiums and ancillary charges cannot be included in the borrowing rate calculation. Banks offering consumer credit with bundled insurance products will need to restructure their pricing to ensure interest applies only to sums actually made available to the borrower.

TGT Boardwalk Draft Conditions Posted Apr 23

PHMSA posted draft conditions related to TGT Boardwalk on the Regulations.gov platform on April 23. The document page indicates that no documents are available to view or download directly, with the substantive content contained in an attachment (PDF) titled '2026-0067 - TGT Boardwalk Draft Conditions'. The page serves as a portal for accessing the draft conditions document rather than presenting the conditions themselves.

Mifflin Energy Declaratory Order

PHMSA issued a declaratory order resolving questions of law and fact specific to Mifflin Energy's operations under the Hazardous Materials Regulations. Declaratory orders are binding final agency actions that establish the legal rights and obligations of the named party. The order was filed in docket PHMSA-2023-0080 and represents PHMSA's formal determination regarding Mifflin Energy's regulatory status or compliance obligations.

Supplement Document No Content Available Apr 23

PHMSA published a supplement document placeholder in docket PHMSA-2022-0038 on April 23, indicating that no documents are currently available to view or download. An attachment (PDF) is referenced but no content has been posted to the record at this time. Stakeholders monitoring this docket should check back for future uploads.

PHMSA CIG DEA FONSI Draft - No Downloadable Content

This is a placeholder page on regulations.gov for PHMSA docket PHMSA-2022-0038. The page title references a PHMSA CIG DEA FONSI (2022 Draft) document but indicates there are no documents available to view or download. The docket relates to a Categorical Exclusion/Decision Memo/Finding of No Significant Impact environmental assessment document under NEPA. The attachment_1.pdf file referenced is not directly accessible from this page.

Segment Maps Attachment — No Content Available

PHMSA docket PHMSA-2026-0067-0004 is a segment maps attachment page indicating no primary documents are available for viewing or download. The docket entry lists one attachment (Attachment B - Segment & IA Maps) available as a PDF download. No regulatory text, requirements, or compliance obligations are contained in this docket entry.

Pipeline Safety RMVs Timeframe PHMSA Supplement

PHMSA published a document titled 'Pipeline Safety RMVs Timeframe PHMSA Supplement' under docket PHMSA-2026-1553-0001 on regulations.gov. The document record contains a PRIA attachment (Pipeline Safety: Timeframe to Make RMVs Operation) but the primary document content is not available for review. This appears to be a supplementary regulatory document related to pipeline safety required maintenance verification timeframes.

PHMSA CIG Attachment A

PHMSA posted an attachment (CIG Attachment A) to docket PHMSA-2022-0038 on April 23. The regulations.gov page contains no viewable or downloadable documents — only a link to an external PDF. This appears to be a placeholder or landing page for an attachment related to a prior PHMSA rulemaking or comment proceeding. No regulatory obligations, deadlines, or enforcement actions are described in the visible content.

TGT Boardwalk Draft Conditions Withdrawn

PHMSA has withdrawn draft conditions for the TGT Boardwalk project upon the agency's own request. The withdrawal notice states that there are no documents available to view or download in connection with this action. This withdrawal appears to be an administrative cleanup action rather than a substantive regulatory decision.

PHMSA Special Permit Segments Listing, Apr 22

This regulations.gov page from PHMSA (docket PHMSA-2026-0067-0003) displays a listing for special permit segments dated April 22. The page indicates that no documents are available to view or download directly on the site; however, Attachment A (a PDF titled 'Listing of Special Permit Segments') is available for download via the provided link. No substantive regulatory text, obligations, deadlines, or penalties are displayed in the visible page content.

PHMSA SPL Cover Letter Redacted Apr 22

PHMSA has posted a redacted cover letter for a Special Permit License (SPL) filing to docket PHMSA-2026-0067 dated April 22. The document attachment (PDF) is available for download; however, no substantive content is available to view on the regulations.gov page, as the cover letter itself has been redacted. This filing represents a procedural docket entry in the PHMSA permit review process.

PRIA: Hazardous Liquid Valve Maintenance Schedule

PHMSA published a Paperwork Reduction Act Information (PRIA) document titled 'Hazardous Liquid Valve Maintenance Schedule' under docket PHMSA-2026-1554. The document was filed on April 23, 2026 on regulations.gov and references attachment_1.pdf containing the full PRIA details. The main document page states there are no documents available to view or download directly. This PRIA relates to hazardous liquid pipeline valve maintenance requirements under PHMSA regulations.

Monkfish Framework Adjustment 17 Proposed Rule

NMFS has proposed Framework Adjustment 17 to the Monkfish Fishery Management Plan, setting catch specifications for fishing years 2026-2028. The proposed measures include a 3-percent decrease in Total Allowable Landing (TAL) for the Northern Fishery Management Area (NFMA) and a less than 1-percent increase for the Southern Fishery Management Area (SFMA). The rule also streamlines the ACL Overage Accountability Measure trigger by shifting responsibility from the Councils to the Regional Administrator, and adds default rollover specifications for years when no specifications are in place. Public comments are due by May 26, 2026.

Guam Bottomfish ACL Increased to 34,500 lb, Accountability Measures Modified

NMFS proposes to increase the annual catch limit (ACL) for Guam Mariana bottomfish management unit species from 31,000 lb (14,061 kg) to 34,500 lb (15,649 kg), representing an 11 percent increase based on 2024 stock assessment showing the stock is no longer overfished. The proposed rule would replace the in-season accountability measure with a post-season overage adjustment triggered when average catch over the most recent 3 years exceeds the ACL, and remove the higher performance standard that indefinitely closes the fishery for any ACL exceedance. Comments must be received by May 26, 2026.

NOAA Decision on Georgina Clemente Appeal F-2025-0300

NOAA has issued a decision on the appeal filed by Georgina Clemente under reference F-2025-0300. The document, available as a PDF download from Regulations.gov, contains the agency's final determination on the matter. No substantive text content was available for analysis; the full decision text must be accessed through the linked PDF document.

Guam Bottomfish Rebuilding Plan Final Rule

NOAA Fisheries has issued a final rule implementing a rebuilding plan for the Guam bottomfish stock complex under the Magnuson-Stevens Fishery Conservation and Management Act. The rule establishes specific conservation measures to rebuild overfished bottomfish populations in Guam waters. Affected fishing operations in Guam must comply with the specified catch limits, gear restrictions, or seasonal closures identified in the rebuilding plan.

NMFS Proposes Aggregate Gag and Black Grouper Vessel Limits

NMFS is seeking public comment through May 26, 2026, on Regulatory Amendment 36 to the Snapper-Grouper Fishery Management Plan for the South Atlantic. The proposed rule would replace separate species-specific vessel limits of two gag and two black grouper per vessel (up to four fish total) with an aggregate limit of two gag or black grouper in any combination, to provide further biological benefits to overfished gag stocks currently under a rebuilding plan expected to complete by 2032. Additionally, the rule would revise transit provisions for commercial fishermen carrying on-demand ropeless black sea bass pots through marine protected areas and spawning special management zones, reducing entanglement risk to protected species such as North Atlantic right whales while allowing practical vessel transit.

Final Supplemental EA and RIR for MHI Bottomfish

NOAA Fisheries has released a Final Supplemental Environmental Assessment (EA) and Regulatory Impact Review (RIR) for the Main Hawaiian Islands (MHI) Bottomfish fishery management. The document supports NOAA's fisheries management program for Pacific island fisheries, addressing environmental assessment requirements for fishing regulations. Commercial bottomfish fishermen operating in Hawaiian waters are subject to the management measures evaluated in this supplemental review.

NOAA Decision on BJG Properties Consistency Appeal

NOAA issued a final decision on BJG Properties' consistency appeal under the Coastal Zone Management Act, determining whether the federal action at issue satisfies state coastal management program requirements. The decision establishes NOAA's finding on the consistency review and any required modifications to achieve compliance with the approved state coastal program. Federal agencies and developers with coastal projects should review this decision to understand the standards applied in CZMA consistency determinations.

OSHA Seeks Public Comments on Gear Certification ICR Extension

OSHA is seeking public comments through June 22, 2026 on extending OMB approval of information collection requirements under the Standard on Gear Certification (29 CFR 1919). The agency requests an adjustment increase of 20 burden hours (from 109 to 129 hours) and estimates 6,187 certifications annually affecting 629 respondents. OSHA specifically requests feedback on the necessity, accuracy, and clarity of the information collection, as well as ways to minimize employer burden.

ONDCP Requests Comments on Drug-Free Communities Data Collection Revisions

The Office of National Drug Control Policy (ONDCP) has published a 60-day notice requesting comments on revisions to its approved information collection for the Drug-Free Communities (DFC) Support Program and Community-Based Coalition Enhancement Grants to Address Local Drug Crisis (CARA) Local Drug Crisis Program. The revised collection covers web-based data collection, surveys, and interviews of DFC and CARA grant award recipients through the DFC & CARA Me system. ONDCP estimates a combined annual burden of 19,642 hours for DFC respondents and 640 hours for CARA Local Drug Crisis respondents to complete required progress reports, Coalition Asset Surveys, and case study interviews.

FDIC PRA Extension Fast Track Generic Clearance Qualitative Feedback OMB 3064-0127

The FDIC seeks public comment by June 22, 2026 on extending OMB Control No. 3064-0127, the Fast-Track Generic Clearance for the Collection of Qualitative Feedback. The extension is without change to the existing collection covering voluntary quality-of-service surveys on bank supervisory processes. Estimated annual burden is 17,000 hours across approximately 20 surveys deploying to an average of 850 respondents each, with each survey taking no more than one hour per respondent.

FDIC Modifies Privacy Act System of Records FDIC-012, Financial Information Management Records

The FDIC is modifying its existing Privacy Act system of records FDIC-012, 'Financial Information Management Records,' updating sections including Authority for Maintenance, Purpose(s), Categories of Individuals, Categories of Records, Record Source Categories, Routine Uses, and Policies for Storage, Retention, and Disposal. The modification action becomes effective April 23, 2026; routine uses become effective May 26, 2026, unless the FDIC makes changes based on comments received. Written comments are due on or before May 26, 2026. New routine uses authorize disclosure for federal statute or treaty compliance, Office of Inspector General audits, and travel administration through GSA and third-party contractors.