Particle-Based Separation of Extracellular Vesicles, University of Idaho, Apr 23, 2026
Summary
The University of Idaho has published patent application US20260109943A1, covering methods, compositions, and kits for isolating extracellular vesicles (EVs) using a chitin-based stationary phase material functionalized with a fusion protein comprising a lactadherin C1C2 domain, a chitin-binding domain (CBD), and an intein. The application, filed October 17, 2025, was published April 23, 2026. CPC classifications include C12N 5/04, C07K 14/46, and C07K 2319/00. Inventors are listed as Ching-An Peng.
“These methods and systems achieve EV isolation more efficiently, at lower cost, and with higher purity and quality of the isolated EVs, as compared to prior technologies.”
About this source
USPTO classification C07K covers peptides: short amino-acid chains that form the backbone of antibodies, hormones, vaccines, and increasingly a wider class of therapeutic modalities. Every newly published application in C07K lands in this feed, around 175 a month. Applications publish 18 months after filing, so this feed reveals what antibody engineering groups, vaccine developers, and plant biotech researchers were working on in the prior year and a half. Watch this if you compete in biologics, file freedom-to-operate analyses on antibody drug candidates, scout acquisition targets in vaccine platforms, or track protein-based agricultural biotech filings.
What changed
The University of Idaho published a patent application for EV isolation methods that use chitin-based stationary phase materials functionalized with a fusion protein combining a lactadherin C1C2 domain, a chitin-binding domain, and an intein. The application was filed October 17, 2025, and published April 23, 2026.
Parties interested in EV-based diagnostics, therapeutics, or research tools should monitor the prosecution of this application, which could affect freedom-to-operate assessments for competing EV isolation technologies once the patent grants. Researchers and manufacturers developing EV isolation kits or workflows may wish to review the claim scope during the examination period.
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
PARTICLE-BASED SEPARATION OF EXTRACELLULAR VESICLES
Application US20260109943A1 Kind: A1 Apr 23, 2026
Assignee
University of Idaho
Inventors
Ching-An Peng
Abstract
Provided herein are methods, compositions, and kits for isolating extracellular vesicles (EVs). These methods and systems achieve EV isolation more efficiently, at lower cost, and with higher purity and quality of the isolated EVs, as compared to prior technologies. The disclosed methods include contacting a sample with a chitin-based stationary phase material functionalized with a fusion protein, wherein the fusion protein comprises i) a lactadherin C1C2 domain, ii) a chitin-binding domain (CBD), and iii) an intein positioned between the lactadherin C1C2 domain and the CBD.
CPC Classifications
C12N 5/04 C07K 14/46 C07K 2319/00
Filing Date
2025-10-17
Application No.
19362156
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