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Paeoniflorin-Isoliquiritigenin Composition Treats Pulmonary Fibrosis

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Summary

The USPTO has published patent application US20260108548A1, assigned to Henan University of Chinese Medicine, covering a therapeutic composition of paeoniflorin and isoliquiritigenin for treating diffuse interstitial pulmonary fibrosis. The application was filed on October 8, 2023 (Application No. 19129203) and names nine inventors including Jiansheng Li and Peng Zhao. The composition is claimed to provide anti-inflammatory, antioxidant, and collagen deposition inhibition effects. Patent applications are informational publications — no examination or grant decision has been made.

“The composition according to the present invention is rich in raw materials, and has the effects of anti-inflammation, antioxidant, inhibiting collagen deposition, etc., and can be effectively used to treat diffuse interstitial pulmonary fibrosis with high economic and social benefits.”

USPTO , verbatim from source
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About this source

USPTO classification A61K covers pharmaceutical preparations: formulations, dosage forms, combination therapies, delivery systems, and the vehicles that carry active ingredients. Every newly published application in A61K lands in this feed, around 245 a month. Applications publish 18 months after filing, so this feed reveals what pharma formulators at major sponsors and generics were working on in the prior year and a half. Watch this if you compete in drug formulation, file freedom-to-operate analyses, scout competitive drug products before clinical readouts, or follow novel delivery platforms like nanoparticles, lipid carriers, and long-acting injectables.

What changed

The USPTO published patent application US20260108548A1 for a composition of paeoniflorin and isoliquiritigenin filed by Henan University of Chinese Medicine. The application claims the composition is useful for treating diffuse interstitial pulmonary fibrosis, with effects including anti-inflammation, antioxidant activity, and inhibition of collagen deposition.

Affected parties — pharmaceutical researchers, drug developers, and manufacturers working in pulmonary fibrosis therapeutics — should monitor this application as it proceeds through examination. The publication of a patent application does not constitute a grant of rights; competitors should assess whether their own R&D programs could overlap with the claimed composition and consider freedom-to-operate analysis.

Archived snapshot

Apr 23, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

COMPOSITION OF PAEONIFLORIN AND ISOLIQUIRITIGENIN AND USE THEREOF

Application US20260108548A1 Kind: A1 Apr 23, 2026

Assignee

HENAN UNIVERSITY OF CHINESE MEDICINE

Inventors

Jiansheng LI, Yange TIAN, Suxiang FENG, Peng ZHAO, Zhouxin REN, Xueqing YU, Xuefang LIU, Haoran DONG, Shuguang YANG

Abstract

The present invention relates to a composition of paeoniflorin and isoliquiritigenin and application thereof. The composition according to the present invention is rich in raw materials, and has the effects of anti-inflammation, antioxidant, inhibiting collagen deposition, etc., and can be effectively used to treat diffuse interstitial pulmonary fibrosis with high economic and social benefits.

CPC Classifications

A61K 31/7048 A61K 31/12 A61P 11/00

Filing Date

2023-10-08

Application No.

19129203

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Last updated

Classification

Agency
USPTO
Published
April 23rd, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Pharmaceutical companies Healthcare providers Manufacturers
Industry sector
3254 Pharmaceutical Manufacturing 6211 Healthcare Providers
Activity scope
Patent application filing Drug composition research Pulmonary fibrosis treatment
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Regulatory Affairs
Topics
Pharmaceuticals Healthcare Product Safety

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