Patent Application: Genome Modification Compositions and Methods

The USPTO has published a new patent application (US20260085301A1) from Confluence Genetics, LLC, detailing compositions and methods for targeting and eliminating cells with pre-determined DNA sequences using Cas12a2 protein. The application was filed on September 19, 2025.

Patent Application for Engineered Pyrococcus Enzymes

The USPTO has published patent application US20260085299A1 for engineered Pyrococcus enzymes designed for improved nucleotide analogue incorporation in DNA sequencing. The application was filed on May 27, 2025.

Method for Efficient Biosynthesis of Rebaudioside M2 Using Glycosyltransferase

The USPTO has published a patent application detailing a method for the efficient biosynthesis of rebaudioside M2 using glycosyltransferase. The assignee, GUILIN LAYN NATURAL INGREDIENTS CORP., claims this method provides an environmentally friendly way to produce rebaudioside M2 with no by-products, potentially reducing production costs.

Bacterial Superoxide Dismutases Patent Application

The USPTO has published a patent application (US20260085297A1) filed by Novozymes A/S for bacterial superoxide dismutases. The application, filed on August 29, 2025, describes polypeptides useful in animal feed additives for improving growth, performance, and health.

Patent Application for Propagator Cells and Phage Propagation Methods

The USPTO has published a new patent application (US20260085296A1) detailing propagator cells and methods for propagating phage, particularly for delivering CRISPR-Cas components via probiotic organisms. The application was filed on December 4, 2025.

Patent Application for AAV Purification Using Anion Exchange Chromatography

The USPTO has published a patent application (US20260085295A1) detailing methods for purifying adeno-associated viruses (AAV) using anion exchange chromatography. The application, filed on September 23, 2025, by inventors Garima Thakur, Sheldon Robert Mink, and Andrew David Tustian, focuses on enhancing purification efficiency and concentration.

Process for Producing Purified Rhabdovirus from Cell Culture

The USPTO has published a patent application detailing a process for producing a purified rhabdovirus from cell culture, specifically oncolytic rhabdoviruses like vesicular stomatitis virus. The application, filed on August 21, 2025, outlines methods for both upstream and downstream processing.

USPTO Patent Application for Body Fluid Sample Transport Solution

The USPTO has published a new patent application (US20260085293A1) detailing a solution and method for transporting or storing body fluid samples. The application, filed on March 27, 2024, by inventors Mitsumi NISHI, Noriko MIYAUCHI, and Rieko SHIMAMURA, describes a solution containing specific active ingredients for sample preservation.

Minimal Essential Media for Human Induced Pluripotent Stem Cells

The USPTO has published a patent application (US20260085292A1) detailing minimal essential media for culturing human induced pluripotent stem cells (iPSCs). The application was filed on September 11, 2023, by inventor Paul Wesley Burridge.

Patent Application: Diabetes Prevention/Treatment by Myeloid Suppressor Cell Activity

The USPTO has published a new patent application (US20260085291A1) from CREATIVE MEDICAL TECHNOLOGIES, INC. The application details methods and compositions for preventing or treating Type 1 diabetes by augmenting myeloid suppressor cell activity, potentially involving conditioned immune cells or exogenous suppressor cells.