Method for Efficient Biosynthesis of Rebaudioside M2 Using Glycosyltransferase
Summary
The USPTO has published a patent application detailing a method for the efficient biosynthesis of rebaudioside M2 using glycosyltransferase. The assignee, GUILIN LAYN NATURAL INGREDIENTS CORP., claims this method provides an environmentally friendly way to produce rebaudioside M2 with no by-products, potentially reducing production costs.
What changed
This document is a published patent application (US20260085298A1) from the USPTO, filed on August 5, 2024, by GUILIN LAYN NATURAL INGREDIENTS CORP. It describes a novel method for synthesizing rebaudioside M2, a component often used in food and pharmaceutical applications, utilizing a specific glycosyltransferase (UGT94D1). The application highlights the efficiency and environmental benefits of this biocatalytic process, noting the absence of by-products which simplifies purification and lowers costs.
While this is a patent application and not a regulatory rule, it signals potential innovation in the production of rebaudioside M2. Companies involved in the production or use of steviol glycosides, particularly rebaudioside M2, should be aware of this patented technology. Compliance officers in the pharmaceutical and food manufacturing sectors may need to monitor the patent's progress and consider its implications for intellectual property and manufacturing processes.
Source document (simplified)
METHOD FOR EFFICIENT BIOSYNTHESIS OF REBAUDIOSIDE M2 USING GLYCOSYLTRANSFERASE
Application US20260085298A1 Kind: A1 Mar 26, 2026
Assignee
GUILIN LAYN NATURAL INGREDIENTS CORP.
Inventors
Yijian RAO, Yan ZHANG, Lifeng YANG, Qian PING
Abstract
The invention provides a method for efficient biosynthesis of rebaudioside M2 using glycosyltransferase, belonging to the technical field of biocatalytic synthesis. A glycosyltransferase UGT94D1 catalyzing rebaudioside D to synthesize rebaudioside M2 is obtained by mining, providing a new, efficient and environmentally friendly way of producing rebaudioside M2. During the whole catalytic reaction process, no by-products are produced, facilitating downstream purification and further reducing production costs.
CPC Classifications
C12N 9/1051 C12N 1/20 C12N 15/70 C12P 19/18 C12P 19/56 C12R 2001/19
Filing Date
2024-08-05
Application No.
19109565
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