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Process for Producing Purified Rhabdovirus from Cell Culture

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Published March 26th, 2026
Detected March 27th, 2026
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Summary

The USPTO has published a patent application detailing a process for producing a purified rhabdovirus from cell culture, specifically oncolytic rhabdoviruses like vesicular stomatitis virus. The application, filed on August 21, 2025, outlines methods for both upstream and downstream processing.

What changed

This document is a published patent application (US20260085294A1) from the USPTO concerning a novel process for producing purified rhabdoviruses from cell cultures. The invention focuses on oncolytic rhabdoviruses, particularly vesicular stomatitis virus, and includes methods for upstream and downstream processing, as well as pharmaceutical compositions containing the virus. The application was filed on August 21, 2025, and published on March 26, 2026.

While patent applications do not impose direct regulatory obligations on entities, this publication signals potential future developments in the biotechnology and pharmaceutical sectors. Companies involved in viral vector development, gene therapy, or oncolytic virus research should review this application to understand emerging technologies and potential intellectual property landscapes. No immediate compliance actions are required, but awareness of this patented process may inform R&D strategies and competitive analysis.

Source document (simplified)

← USPTO Patent Applications

PROCESS FOR PRODUCING A PURIFIED RHABDOVIRUS FROM CELL CULTURE

Application US20260085294A1 Kind: A1 Mar 26, 2026

Inventors

Dethardt MUELLER, Alan Pardo GARCIA, Tanja Anneliese GREIN, Friedrich KAESS, Judy NG, Katharina PESTA, Sabrina SCHNEIDER, Jordan TURNBULL

Abstract

The present invention relates to the field of upstream and downstream processing and provides a process for producing a purified rhabdovirus from a cell culture, preferably a purified oncolytic rhabdovirus and in particular a vesicular stomatitis virus, including pharmaceutical compositions comprising the rhabdovirus.

CPC Classifications

C12N 7/00 C12N 2760/20221 C12N 2760/20252

Filing Date

2025-08-21

Application No.

19306563

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Named provisions

Abstract

Classification

Agency
USPTO
Published
March 26th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260085294A1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Viral Vector Production Drug Manufacturing
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Research & Development
Topics
Biotechnology Medical Research

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