Process for Producing Purified Rhabdovirus from Cell Culture
Summary
The USPTO has published a patent application detailing a process for producing a purified rhabdovirus from cell culture, specifically oncolytic rhabdoviruses like vesicular stomatitis virus. The application, filed on August 21, 2025, outlines methods for both upstream and downstream processing.
What changed
This document is a published patent application (US20260085294A1) from the USPTO concerning a novel process for producing purified rhabdoviruses from cell cultures. The invention focuses on oncolytic rhabdoviruses, particularly vesicular stomatitis virus, and includes methods for upstream and downstream processing, as well as pharmaceutical compositions containing the virus. The application was filed on August 21, 2025, and published on March 26, 2026.
While patent applications do not impose direct regulatory obligations on entities, this publication signals potential future developments in the biotechnology and pharmaceutical sectors. Companies involved in viral vector development, gene therapy, or oncolytic virus research should review this application to understand emerging technologies and potential intellectual property landscapes. No immediate compliance actions are required, but awareness of this patented process may inform R&D strategies and competitive analysis.
Source document (simplified)
PROCESS FOR PRODUCING A PURIFIED RHABDOVIRUS FROM CELL CULTURE
Application US20260085294A1 Kind: A1 Mar 26, 2026
Inventors
Dethardt MUELLER, Alan Pardo GARCIA, Tanja Anneliese GREIN, Friedrich KAESS, Judy NG, Katharina PESTA, Sabrina SCHNEIDER, Jordan TURNBULL
Abstract
The present invention relates to the field of upstream and downstream processing and provides a process for producing a purified rhabdovirus from a cell culture, preferably a purified oncolytic rhabdovirus and in particular a vesicular stomatitis virus, including pharmaceutical compositions comprising the rhabdovirus.
CPC Classifications
C12N 7/00 C12N 2760/20221 C12N 2760/20252
Filing Date
2025-08-21
Application No.
19306563
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