Patent Application for Engineered Pyrococcus Enzymes
Summary
The USPTO has published patent application US20260085299A1 for engineered Pyrococcus enzymes designed for improved nucleotide analogue incorporation in DNA sequencing. The application was filed on May 27, 2025.
What changed
This document is a publication of a patent application (US20260085299A1) filed with the USPTO. The application describes modified Archaeal family B polymerases derived from Pyrococcus species, which exhibit enhanced incorporation of nucleotide analogues for DNA sequencing applications. The inventors listed are Souad NAJI, Eli N. GLEZER, Youngjin CHO, Zachary TERRANOVA, and Abrehet ABDU.
As this is a patent application, it does not impose immediate regulatory obligations or compliance deadlines on regulated entities. However, companies involved in biotechnology, DNA sequencing, or enzyme engineering should review the application for potential intellectual property considerations and future licensing opportunities. The filing date was May 27, 2025.
Source document (simplified)
ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF
Application US20260085299A1 Kind: A1 Mar 26, 2026
Inventors
Souad NAJI, Eli N. GLEZER, Youngjin CHO, Zachary TERRANOVA, Abrehet ABDU
Abstract
Provided herein are modified Archaeal family B polymerases derived from species of the Archaeal microorganism Pyrococcus that exhibit improved incorporation of nucleotide analogues utilized in DNA sequencing.
CPC Classifications
C12N 9/1252 C12N 15/63 C12Q 1/6874 C12Y 207/07007
Filing Date
2025-05-27
Application No.
19219723
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