This document is a publication of a patent application filed by Confluence Genetics, LLC, titled 'Compositions and Methods for Modifying Genomes.' The application, identified as US20260085301A1, describes novel DNA constructs encoding a Cas12a2 protein and methods for using these constructs to selectively target and eliminate cells that harbor specific pre-determined DNA sequences. The filing date for this application was September 19, 2025.

As this is a patent application, it does not impose immediate regulatory obligations or penalties on companies. However, it signals potential future intellectual property developments in the field of genome modification and biotechnology. Companies operating in this space, particularly those involved in gene editing or cell therapy, should monitor the progress of this patent application and similar filings to understand evolving technological landscapes and potential licensing or infringement considerations.