USPTO Patent Grant: Pyridone Derivative Crystal Form

The USPTO has granted a patent to Jiangxi Caishi Pharmaceutical Technology Co., Ltd. for a novel pyridone derivative crystal form and its preparation method. This patent covers specific crystal forms and their application in treating influenza, potentially offering improved efficacy and bioavailability.

USPTO Patent Grant: JAK Inhibitors Synthesis Methods

The USPTO has granted patent US12583868B2 for novel JAK inhibitors and methods for their synthesis and use, assigned to Galderma Holding SA. The patent covers compounds with formula (I) and their application in treating various diseases.

A2A Receptor Antagonist Salt and Crystal Forms

The USPTO has granted patent US12583869B2 for a salt form and crystal form of an adenosine A2A receptor antagonist, along with its preparation method. The patent, assigned to CSTONE PHARMACEUTICAL (SUZHOU) CO., LTD., also covers the application of these forms in preparing medicine for A2A receptor-related diseases.

USPTO Patent Grant US12583859B2 for PRMT5 Inhibitors

The USPTO has granted patent US12583859B2 to the California Institute of Technology for PRMT5 inhibitors. The patent covers compounds and methods useful in treating cancers and other diseases.

USPTO Patent Grant: PSMA Imaging Agents

The United States Patent and Trademark Office (USPTO) has granted patent US12583887B2 to Siemens Medical Solutions USA, Inc. for PSMA imaging agents. The patent covers compounds and methods for imaging prostate-specific membrane antigen (PSMA), suitable for PET and SPECT imaging.

Azaheteroaryl Compound Patent Granted

The USPTO has granted patent US12583870B2 to SHANGHAI BLUERAY BIOPHARMA CO., LTD. for an azaheteroaryl compound and its preparation method. This patent covers compounds and compositions for treating diseases related to EED protein and PRC2 protein complex mechanisms.

USPTO Grants PRMT5 Inhibitors Patent to Merck Sharp & Dohme

The USPTO has granted a new patent (US12583871B2) to Merck Sharp & Dohme LLC for PRMT5 inhibitors. The patent covers compounds and methods for treating conditions such as cancer, sickle cell, and hereditary persistence of foetal hemoglobin.

USPTO Patent Grant for PCSK9 Inhibitors

The USPTO has granted a patent (US12584120B2) to AstraZeneca AB for novel PCSK9 inhibitors and methods of use. The patent covers specific heteroaryl compounds that bind the PCSK9 protein, aiming to advance treatments for conditions related to cholesterol regulation.

USPTO Patent Grant: Light-Emitting Element with Long Lifetime

The USPTO has granted a patent (US12588408B2) to Semiconductor Energy Laboratory Co., Ltd. for a novel light-emitting element. The patent describes an element with a long lifetime and high efficiency, utilizing specific organic acceptor and host materials in its electron-transport layers.

USPTO Patent Grant: Daprodustat Crystal Form M Preparation and Use

The USPTO has granted patent US12583823B2 for a specific crystal form (crystal form M) of the drug daprodustat, a proline hydroxylase inhibitor. The patent covers the preparation method and use of this crystal form, which exhibits improved stability and solubility characteristics.

Neighborhood Reinvestment Corporation Sunshine Act Meeting Notice

The Neighborhood Reinvestment Corporation has issued a notice for a Special Board of Directors meeting to be held on March 30, 2026. The meeting will include both open and closed sessions, with the closed session pertaining to the FY26 Final Budget.

Missouri Agencies Alert Public to Rising Nitazene Threat

Missouri state agencies have issued a joint warning about the increasing presence of nitazenes, a potent synthetic opioid, detected in wastewater and illicit substances across the state. The alert urges public vigilance, prevention measures, and expanded access to naloxone, a life-saving overdose reversal medication.

Tri City Electric Service LLC Installer Certification Application

The Illinois State PUC received an application from Tri City Electric Service, LLC for certification as an installer of distributed generation facilities. This application was filed on March 24, 2026, under Section 16-128A of the Public Utilities Act.

Solarize LLC Installer Certification Application

The Illinois State PUC received an application from Solarize LLC for certification as an installer of distributed generation facilities. This filing pertains to case number P2026-0272 and is part of the ongoing process for installer certification under the Public Utilities Act.

Commonwealth Edison Company Expedited Petition for Rate Increase Waiver

Commonwealth Edison Company has filed an expedited petition with the State PUC for a waiver of certain rate increase provisions. The filing seeks to bypass standard information requirements for public utilities seeking rate hikes. The case is currently in its initial administrative phase with action pending.

Telecom Docket 26-999-03 Utility Comments and Filings

The Utah Public Service Commission has posted various filings related to Telecom Docket No. 26-999-03. These include comments from the Division of Public Utilities, applications to discontinue services, and notifications regarding telephone number requests and withdrawal from reporting requirements.

Kern River Gas Transmission Co. FERC Filing

The Utah Public Service Commission has posted miscellaneous correspondence and reports regarding gas utility services for 2026. These filings include annual reports, tariff revisions, and service agreement updates from various gas transmission companies, such as Kern River Gas Transmission Company and Colorado Interstate Gas Company, LLC.

Zayo Network Services LLC Telecom Application Utah

Zayo Network Services, LLC has applied for a Certificate of Public Convenience and Necessity to provide telecommunications services within Utah. The State Public Service Commission is reviewing the application, with various filings and comment periods scheduled throughout 2025 and 2026.

NY DEC 2025 Hunting Safety Statistics

The New York State Department of Environmental Conservation (DEC) has released its 2025 hunting safety statistics, reporting the safest season on record with seven hunting-related shooting incidents (HRSI) and no fatalities. The report also noted nine falls from tree stands, including one fatality, and emphasized the importance of safety protocols for both HRSI and elevated hunting incidents.

Remote Access Security Act Expands US Export Controls on Cloud Services

The House of Representatives passed the Remote Access Security Act (RASA), which would expand the Bureau of Industry and Security's (BIS) authority to regulate remote access to export-controlled items via cloud services. This legislation aims to close a perceived loophole in current US export control regulations.

CBP Outlines IEEPA Duty Refund Framework via CAPE System

U.S. Customs and Border Protection (CBP) has provided details on its framework for refunding duties imposed under the International Emergency Economic Powers Act (IEEPA) via the CAPE system in ACE. This follows a Supreme Court decision that IEEPA does not authorize the President to impose tariffs. The CIT has suspended immediate compliance pending the development of this administrative refund process.

Supreme Court Strikes Down IEEPA Tariffs, Increasing Enforcement Risk

The Supreme Court has struck down tariffs imposed under the International Emergency Economic Powers Act (IEEPA), creating refund opportunities for importers. However, this ruling increases enforcement risk, as refund claims will trigger scrutiny of past classifications, valuations, and disclosures, potentially leading to False Claims Act and securities law violations.

Investor-State Arbitration Over Russian Sanctions

Moldovan billionaire Igor Viktorovich Makarov has filed a C$350 million claim against Canada with the International Centre for the Settlement of Investment Disputes (ICSID). The claim arises from sanctions imposed on Makarov, which he alleges destroyed the value of his investment in Spartan Delta, a Canadian company.

IRS Notice 2026-15: Material Assistance Under Foreign Entity of Concern Rules

The IRS issued Notice 2026-15, providing interim guidance on calculating material assistance costs for clean energy tax credits under new Foreign Entity of Concern (FEOC) rules. The notice details the Material Assistance Cost Ratio methodology and offers three safe harbors, but leaves open questions regarding 'effective control' triggers for Prohibited Foreign Entities.

UK REACH SVHC Candidate List Alignment with EU

The UK government has announced a new strategic approach to adding Substances of Very High Concern (SVHC) to the UK REACH Candidate List, aligning more closely with the EU's approach. This involves a consultation on adding 15 SVHCs, with further additions expected.

Tariff Refund Lawsuits Against Retailers Following Supreme Court Decision

Following a Supreme Court decision ordering tariff refunds, multiple class action lawsuits have been filed against retailers and consumer goods companies. These suits allege that companies seeking refunds for tariffs they passed on to consumers are poised to obtain an improper 'double recovery.' The article advises companies that passed tariff costs to consumers and are now seeking refunds to conduct an urgent legal review.

CIT Amends Order on IEEPA Tariff Refunds for Brazil and India

The Court of International Trade (CIT) amended its March 4 Order to clarify that it applies to all duties imposed under IEEPA, including those on Brazil and India. The court emphasized importers should be aware of protest remedies available under 19 U.S.C. § 1514.

China's New Trade Secret Protection Rules

China's State Administration for Market Regulation (SAMR) has issued new Provisions on the Protection of Trade Secrets, effective June 1, 2026. These replace 1995 rules and significantly expand the scope of protectable information, including technical data like AI datasets and commercial data such as customer information, aligning protection with the digital economy.

ECB Opens Doors for Night of the Museums

The European Central Bank (ECB) announced it will participate in Frankfurt's Night of the Museums on April 25, 2026. The public will have access to certain areas of the Grossmarkthalle for guided tours focusing on art and architecture, as well as a complementary program of music, talks, and interactive games.

Digital Euro Preparation Focuses on Inclusion, Accessibility, Innovation

The European Central Bank (ECB) provided an update on the digital euro initiative, emphasizing preparations for inclusion, accessibility, and innovation. The speech highlighted ongoing technical work, collaboration with disability foundations, and plans for piloting the digital euro to ensure it serves all euro area citizens.

IVASS Report: 2024 Insurance Disputes R.C. Auto Natanti

IVASS has published its 2024 statistical bulletin on insurance disputes concerning R.C. Auto and Natanti (watercraft). The report indicates a decrease in pending cases and provides insights into case resolution rates, average reserves, and management efficiency by regulated insurers.

IVASS Orders Block of 5 Abusive Insurance Websites

The Italian Insurance Supervisory Authority (IVASS) has ordered the blocking of five abusive websites that were illegally offering insurance services. This action brings the total number of blocked abusive sites to 357 since November 2023. IVASS advises consumers to be wary of suspicious payment methods and to verify intermediaries against official lists.

Domestic RHI Tariff Table 2026-2027

Ofgem has published the tariff table for the Domestic Renewable Heat Incentive (RHI) scheme for the 2026 to 2027 period. This data publication provides the rates payable in pence per kilowatt-hour of heat for installations accredited to the scheme.

CRS Properties LLC v. William J. Mossuto - Wisconsin Court of Appeals

The Wisconsin Court of Appeals has released a new opinion in the case of CRS Properties LLC v. William J. Mossuto, docket number 2024AP001738. This opinion is now available in PDF format and will be published in the official reports after any final editing.

Roger Brazeau v. NuMale Wisconsin GB - Case 2024AP002147

The Wisconsin Court of Appeals has released its opinion for case 2024AP002147, Roger Brazeau v. NuMale Wisconsin GB, S.C. The opinion was issued on March 24, 2026, and is available in PDF format.

State v. Jeremy Jamon Pierson - Criminal Appeal

The Wisconsin Court of Appeals has issued an opinion in the criminal case State v. Jeremy Jamon Pierson, case number 2024AP002161. The opinion was released on March 24, 2026, and is available in PDF format.

State v. Zachary Scott Schullo - Criminal Appeal

The Wisconsin Court of Appeals has issued an opinion in the criminal case State v. Zachary Scott Schullo. The opinion is dated March 24, 2026, and pertains to docket number 2024AP002331-CR.

State v. Abraham Rodriguez - Criminal Appeal

The Wisconsin Court of Appeals has issued an opinion in the case of State v. Abraham Rodriguez, docket number 2024AP001721. The opinion was released on March 24, 2026, and is available in PDF format.

State v. Anthony John Valdez - Criminal Appeal

The Wisconsin Court of Appeals has released its opinion in the criminal appeal case 2023AP002055, State v. Anthony John Valdez. The opinion is available in PDF format and will be published in the official reports.

State v. Terrance L. Millighan - Criminal Appeal

The Wisconsin Court of Appeals has released its opinion in case 2024AP000370-CR, State v. Terrance L. Millighan. The opinion is dated March 24, 2026, and concerns a criminal appeal from Milwaukee County.

State v. Jasmeine Monique Steber - Criminal Appeal

The Wisconsin Court of Appeals has released an opinion in the criminal appeal case State v. Jasmeine Monique Steber (Case No. 2024AP002452-CR). The opinion is dated March 24, 2026, and is available in PDF format.

State v. Jasmeine Monique Steber - Criminal Appeal

The Wisconsin Court of Appeals has released its opinion in the criminal appeal case State v. Jasmeine Monique Steber, docket number 2024AP002453-CR. The opinion was released on March 24, 2026, and is subject to further editing before appearing in the official reports.

State v. Alonzo Lee Peavy - Wisconsin Court of Appeals

The Wisconsin Court of Appeals has released an opinion in the case of State v. Alonzo Lee Peavy, docket number 2024AP002568. The opinion is dated March 24, 2026, and is available in PDF format.

P. B. v. J. T. B. - Wisconsin Court of Appeals Case 2025AP000226

The Wisconsin Court of Appeals has issued an opinion in case 2025AP000226, P. B. v. J. T. B. The opinion was released on March 24, 2026, and pertains to a case originating in Marathon County. This is a published opinion, meaning it may be subject to further editing before appearing in the official reports.

Petitioner v. Paul Gerald Chojnacki - Wisconsin Court of Appeals Case

The Wisconsin Court of Appeals has released an opinion for case 2025AP001525, titled Petitioner v. Paul Gerald Chojnacki. The opinion was issued on March 24, 2026, and is available in PDF format. Published opinions may be subject to further editing before appearing in the official reports.

State v. Armstead - Prison Term Ruling Reversed and Remanded

The Ohio Court of Appeals reversed and remanded a criminal sentence imposed on William D. Armstead, Jr. The court found that the trial court erred in designating the two-year prison term for felonious assault as non-mandatory, when it was required by statute due to a firearm specification. This decision impacts how mandatory and non-mandatory prison terms are applied in similar cases.

State ex rel. Yost v. Best Choice Industries, L.L.C. - Denial of Motion to Vacate Judgment

The Ohio Court of Appeals affirmed the denial of a motion to vacate a default judgment against Best Choice Industries, LLC and Daniel Perley. The court found that the trial court did not err in its legal standard or abuse its discretion regarding service of process.

McDonald v. Foos - Contract Dispute Affirmation

The Ohio Court of Appeals affirmed a jury verdict in a contract dispute case involving an estate. The court found no reversible error in the exclusion of certain statements or in the jury instructions regarding prevention of performance.

State v. Thompson - Theft Appeal Moot Due to Sentence Completion

The Ohio Court of Appeals dismissed an appeal filed by Holly Thompson in a theft case. The court found the appeal moot because Thompson completed her jail-time sanction, rendering the merits of her assignments of error unaddressable. The original indictment was for theft of merchandise valued between $1,000 and $7,500.

White v. Ross Corr. Inst. - Public Records and Redaction Dispute

The Ohio Court of Appeals reversed in part a Court of Claims decision regarding a public records request. The appellate court found that the respondent failed to properly certify service of objections via certified mail, thus the Court of Claims erred in considering those objections. The case is remanded for further proceedings.