A2A Receptor Antagonist Salt and Crystal Forms
Summary
The USPTO has granted patent US12583869B2 for a salt form and crystal form of an adenosine A2A receptor antagonist, along with its preparation method. The patent, assigned to CSTONE PHARMACEUTICAL (SUZHOU) CO., LTD., also covers the application of these forms in preparing medicine for A2A receptor-related diseases.
What changed
The United States Patent and Trademark Office (USPTO) has issued patent US12583869B2, covering specific salt and crystal forms of an adenosine A2A receptor antagonist. The patent details the preparation method for these forms and their application in treating A2A receptor-related diseases, with the maleate salt structure specified. The patent was granted to CSTONE PHARMACEUTICAL (SUZHOU) CO., LTD.
This patent grant signifies a new intellectual property right for the assignee, potentially impacting future drug development and manufacturing processes related to A2A receptor antagonists. While this is a patent grant and not a regulatory rule imposing direct compliance obligations on other entities, it establishes exclusive rights that may influence market entry and research activities in this therapeutic area. Companies operating in the pharmaceutical sector, particularly those involved in developing treatments for A2A receptor-related diseases, should be aware of this granted patent.
Source document (simplified)
Salt form and crystal form of A2A receptor antagonist and preparation method therefor
Grant US12583869B2 Kind: B2 Mar 24, 2026
Assignee
CSTONE PHARMACEUTICAL (SUZHOU) CO., LTD.
Inventors
Kevin X Chen, Kai Zhou, Yanxin Yu, Boyu Hu, Li Zhang, Zhaoguo Chen
Abstract
Provided are a salt form and a crystal form of adenosine A2A receptor antagonist, and preparation method therefor. Also provided is an application of the salt form or crystal form in the preparation of a medicine for A2A receptor-related diseases, the maleate salt in the salt form has a structure of formula (I).
CPC Classifications
C07D 519/00 C07B 2200/13 Y02A 50/30 A61P 35/00 C07C 57/145 C07C 309/04 C07C 309/30
Filing Date
2020-03-27
Application No.
17442688
Claims
4
Named provisions
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