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Patent Application: Therapeutic Compounds - Orexin-1 Receptor Antagonists

The USPTO has published a new patent application (US20260085060A1) for therapeutic compounds that act as orexin-1 receptor antagonists. The application, filed on September 25, 2025, details compounds with structural formula (I), their preparation, and pharmaceutical uses.

Routine Notice Pharmaceuticals
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System for updating medical facility uses AI

The USPTO has published a patent application for a system that uses AI to determine whether to update a medical facility. The system retrieves information from the facility, applies an AI model, and initiates maintenance or upgrades based on the determination. The application was filed on September 4, 2023.

Routine Notice Healthcare
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Patent Application US20260085058A1 for SOS1 Degraders Treating Cancers

The USPTO has published patent application US20260085058A1, which relates to compounds that degrade son of sevenless homolog 1 (SOS1) and their use in treating cancers, particularly KRAS-mutant cancers. The application was filed on August 11, 2023.

Routine Notice Pharmaceuticals
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Substituted Indazoles for Treating Animal Allergic Inflammatory Diseases

The USPTO has published a patent application detailing the use of substituted indazoles for the treatment and prevention of allergic and inflammatory diseases in animals. The application, filed on October 9, 2025, outlines specific compounds and their potential applications in veterinary medicine.

Routine Notice Pharmaceuticals
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OX1 Receptor Antagonists Patent Application

The USPTO has published a new patent application (US20260085056A1) filed on May 9, 2025, by NXERA PHARMA UK LIMITED. The application relates to novel compounds for treating neurological or psychiatric disorders associated with orexin receptors.

Routine Notice Pharmaceuticals
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Patent Application for Recyclable Polymer Material and Monomer

The USPTO has published a patent application (US20260085055A1) for a novel monomer and a chemically recyclable polymer material comprising the same. The application, filed by the Korea Institute of Science and Technology, describes a monomer formed by bonding a pentagonal cyclic olefin molecule with a photosensitive molecule to enable chemical recycling.

Routine Notice Intellectual Property
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Hispidin Derivative Synthesis Method and Use

The USPTO has published a patent application (US20260085054A1) detailing a new method for synthesizing Hispidin derivatives and their use in preparing lipid-lowering drugs. The application describes a process using readily available starting materials with potential for large-scale industrial application.

Routine Notice Pharmaceuticals
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Patent Application for Benzofuran Derivatives as SIK Inhibitors

The USPTO has published a patent application (US20260085053A1) from BEONE MEDICINES I GMBH for benzofuran derivatives that act as SIK inhibitors. These compounds are intended for the treatment of various inflammatory diseases.

Routine Notice Pharmaceuticals
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Patent Application for Furan Derivative Oxidation Process

The USPTO has published a patent application (US20260085052A1) detailing a new process for producing 2,5-furandicarboxylic acid. The application, filed by David Lee Sikkenga and Jan Hendrik Blank, describes a specific oxidation method involving furan derivatives, oxidants, solvents, and catalysts.

Routine Notice Pharmaceuticals
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Patent Application for 2-Chloro-4-Fluoro-5-Nitrobenzoic Acid Preparation

The USPTO has published a patent application (US20260085051A1) detailing a novel nitration process for preparing 2-chloro-4-fluoro-5-nitrobenzoic acid. The assignee is ADAMA AGAN LTD. This compound is used in the synthesis of the herbicide saflufenacil.

Routine Notice Pharmaceuticals

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