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2,365 changes Pharma & Drug Safety
Patent Application: Detecting Pancreatic Cancer
The USPTO has published a patent application (US20260085360A1) detailing methods for detecting pancreatic cancer. The application describes a method involving measuring CA19-9 levels alongside other markers like OPN, MIA, and CEACAM-1 in a subject's sample.
Patent Application: Cancer Treatment Compositions and Methods
The USPTO has published a new patent application (US20260085120A1) for compositions and methods related to cancer treatment. The application describes binding agents, carrier proteins, and therapeutic agents, particularly for cancers expressing PD-LI or PD-L2, and lyophilized compositions.
Patent Application for Treating Cancer with Anti-CTLA4 Antibodies
The USPTO has published a new patent application (US20260085119A1) from ADAGENE PTE. LTD. for methods of treating cancers using anti-CTLA4 antibodies. The application details compositions and treatment methods, including combination therapies for cancers resistant to PD-1 or PD-L1 inhibitors.
Anti-CTLA-4 Antibody Conjugate Activated by Tumor Microenvironment
The USPTO has published a patent application (US20260085118A1) for a novel conjugate of an anti-CTLA-4 antibody activated by the tumor microenvironment. The application details a dual-activated conjugate designed to improve targeting efficacy, overcome drug resistance, and reduce toxicity.
Anti-GPRC5D Antibody for Cancer Treatment
The USPTO has published a patent application (US20260085114A1) filed by Kyinno Biotechnology Co., Ltd. The application describes an anti-G protein-coupled receptor family class C group 5 member D (GPRC5D) antibody or fragment thereof for the treatment of tumors or cancers. It also details a bispecific antibody targeting GPRC5D and CD3.
CD3 Binding Antibodies Patent Application Inventors Listed
The USPTO has published a new patent application, US20260085115A1, related to CD3 binding antibodies. The application, filed on June 2, 2025, lists inventors Nathan Trinklein, Wim van Schooten, Shelley Force Aldred, Katherine Harris, and Duy Pham.
Patent Application: Antibody Heavy Chain Regions Reduce Fc Gamma Receptor Binding
The USPTO has published a patent application (US20260085116A1) detailing antibody heavy chain constant regions modified to reduce binding to Fc gamma receptors. This modification, achieved through specific residue replacements or deletions in the hinge region, aims to decrease effector functions in antibodies and Fc fusion proteins.
Patent Application: Compositions with Sophorolipids and Lactic Acid
The USPTO has published a new patent application (US20260083655A1) filed by Evonik Operations GmbH. The application describes compositions containing sophorolipids and lactic acid for cleaning or skin moisturizing. This is a routine filing for a new patent application.
Patent Application: Tumor Targeting Methods and Reagents
The USPTO has published a patent application (US20260083867A1) detailing methods and reagents for tumor targeting in cancer treatment. The application, filed on November 21, 2025, describes a combination therapeutic approach using agents with different biodistributions to enhance efficacy and reduce toxicity.
USPTO Patent Application for PSMA Ligands
The USPTO has published a new patent application (US20260083865A1) filed by 3B Pharmaceuticals GMBH for prostate specific membrane antigen (PSMA) ligands. The application details a compound of Formula (I) and its use in treating cancer.
USPTO Patent for Orally Administered Corticosteroid Compositions
The USPTO has published a new patent application, US20260083668A1, for orally administered corticosteroid compositions. The patent, filed on November 28, 2025, by inventors Stephen Perrett, Fredric Jay Cohen, and Gopi M. Venkatesh, details pharmaceutical compositions and methods for treating gastrointestinal inflammation.
USPTO Patent Application for Disease Treatment Method
The USPTO has published patent application US20260083666A1 for a method of treating diseases and ameliorating pain by administering a composition to the ear canal. The application was filed on April 10, 2025, and published on March 26, 2026.
USPTO Patent for Implantable Biodegradable Drug Delivery Devices
The USPTO has published a patent application (US20260083665A1) for implantable and biodegradable drug delivery devices. The invention aims to deliver active pharmaceutical ingredients directly to target tissue sites using layered biodegradable polymers.
Sulforaphane Supplement in Gummy Form Patent Application
The USPTO has published a patent application (US20260083667A1) for a sulforaphane supplement in gummy form. The application, filed by Sensory Scout LLC, describes a composition including sulforaphane, glucoraphanin, and myrosinase immobilized within a gummy matrix. This represents a new patent filing for a novel supplement formulation.
Patent Application: Intrathecal T regulatory cells for Multiple Sclerosis Treatment
The USPTO has published a patent application (US20260083664A1) for a medicinal product involving intrathecal administration of T regulatory cells for treating multiple sclerosis. The application was filed on December 3, 2025, by inventors Piotr Trzonkowski and Kamil Chwojnicki.
Botanical Compositions and Methods of Production and Use
The USPTO has published a new patent application, US20260083663A1, detailing botanical compositions with plant extracts and their preparation methods. The application was filed on September 11, 2023, and is scheduled for publication on March 26, 2026. This represents a new disclosure of potential intellectual property in the pharmaceutical sector.
Patent Application for Contrast Agents in Diagnostic Imaging
The USPTO has published a patent application (US20260083864A1) for a new class of compounds intended for use as contrast agents in diagnostic imaging, including computed tomography (CT) and magnetic resonance imaging (MRI). The application details specific compound formulas, metal chelates, and preparation methods.
Patent Application for Genome Editing Compositions and Methods
The USPTO has published a new patent application (US20260083860A1) for genome editing compositions and methods. The application, filed on August 19, 2025, by inventors Oscar ALVAREZ, Ming-Yue LEE, and Blair B. MADISON, details methods and compositions for functional genetic modifications.
CRISPR Methods Targeting CD70 Expression for Engineered Cells
The USPTO has published a patent application (US20260083861A1) filed by Editas Medicine, Inc. The application describes CRISPR-related systems and methods for targeting the CD70 gene expression in engineered cells, particularly T cells, for potential therapeutic applications.
Patent Application: Treating Brain Diseases with rAAV Particles
The USPTO has published a new patent application (US20260083862A1) from the University of Iowa Research Foundation detailing methods for treating brain diseases using rAAV particles administered via the cisterna magna. The application was filed on May 19, 2025.
Patent Application for Whitening Cosmetic Composition with Artemisinic Acid
The USPTO has published a patent application (US20260083657A1) for a whitening cosmetic composition containing artemisinic acid, nicotinamide, and/or glutathione. The application, filed by Yunnan Botanee Bio-Technology Group Co., Ltd., describes a formulation designed to inhibit melanin production and reduce skin irritation.
Skincare Therapeutic Balm Preparation Method Patent Application
The USPTO has published a patent application (US20260083662A1) for a skincare and therapeutic balm preparation method. The application, filed by Fine Washed LLC, details a method combining Ethiopian black seed oil with Illinois sourced beef tallow.
Cleansing composition with carnosine, magnesium, caffeine
The USPTO has published a new patent application (US20260083658A1) for a personal cleansing composition. The composition includes carnosine, magnesium salt, caffeine, and transdermal absorption enhancers, designed for use in products like shower gels and soaps.
Oil-in-water emulsions for topical administration with hyaluronan
The USPTO has published a patent application (US20260083673A1) for oil-in-water emulsions containing hyaluronan for topical administration. The application details formulations for treating various dermatological conditions, including inflammatory dermatoses, acne, alopecia, and fibrosing pathologies.
Patent Application for Stabilized Galectin-9 Protein Pharmaceutical Formulation
The USPTO has published a patent application (US20260083671A1) for a stabilized pharmaceutical formulation containing a recombinant stabilized galectin-9 protein. The application details a formulation designed for improved stability through the combination of a buffer and a stabilizer.
Adenovirus Formulation with Citrate Buffer and Salt
The USPTO has published a new patent application (US20260083670A1) for an adenovirus formulation. The formulation includes a recombinant adenovirus, citrate buffer, cyclodextrin compound, and salt, with a pH between 5.5 and 6.5, and is free of non-ionic detergent. The invention also covers a method for preserving adenoviruses using this formulation.
Aqueous Gel Composition for Administering Active Agents
The USPTO has published a new patent application, US20260083669A1, filed by Acousia Therapeutics GmbH. The application describes an aqueous gel composition useful for administering pharmaceutically active agents, particularly for transtympanic administration.
Patent Application for Hyaluronic Acid Production Stimulation
The USPTO has published a new patent application (US20260083656A1) filed by Alastin Skincare, Inc. The application details compositions and methods for stimulating intrinsic hyaluronic acid production to improve skin moisture and elasticity. This is a routine publication of a patent application.
KARENZA Trademark Intent to Use Application
The USPTO has received an intent-to-use trademark application for the mark 'KARENZA' for use with dietary supplements. The application was filed on March 24, 2026, and is designated for Class 005.
Vitaminloft Intent to Use Trademark Application
The USPTO has published details for an intent-to-use trademark application for the mark 'VITAMINLOFT'. The application covers a wide range of pharmaceutical and health-related products, including supplements, vitamins, topical preparations, and disinfectants.
FIBRIBION Trademark Publication
The USPTO has published the FIBRIBION trademark application for opposition. The application covers nutritional supplements, probiotic compositions, and dietary supplements. The publication date is March 25, 2026.
CHIGGER OFF Intent to Use Trademark Application
The USPTO has received an Intent to Use trademark application for 'CHIGGER OFF' for topical dermatological preparations. The application was filed on March 24, 2026, with an effective date of March 25, 2026. This filing pertains to a new product intended to treat insect bites and stings.
7 LIFE Trademark Application Published for Opposition
The USPTO has published the trademark application for '7 LIFE' for opposition. The application, filed on March 24, 2026, is for dietary supplements. The publication date is March 25, 2026, initiating a period for potential opposition.
TEMIMAR trademark application published for opposition
The USPTO has published the trademark application for 'TEMIMAR' for opposition. The application covers natural herbal supplements, vitamin supplements, and other health-related food products. The publication date is March 25, 2026.
POWERSTOVE Trademark Application Published for Opposition
The USPTO has published the trademark application for 'POWERSTOVE' for opposition. The application covers a range of products including personal sexual lubricants, dietary supplements, pet supplements, vitamins, and other health-related items. The publication date for opposition is March 25, 2026.
HIVANO Intent to Use Trademark Application
The USPTO has received an intent-to-use trademark application (TM99722503) for the mark 'HIVANO'. The application covers a wide range of goods including athletic apparel, footwear, and various supplements (probiotic, homeopathic, mineral, herbal, vitamin, calcium, food, dietary, nutritional, and natural herbal). It also includes services related to nutrition counseling and information provision.
PRÜF Intent to Use Trademark Application Filed
The USPTO has received an intent-to-use trademark application for the mark 'PRÜF' filed on March 25, 2026. The application, filed on September 24, 2025, pertains to dietary and nutritional supplements.
JOINT AND JOINT Trademark Published for Opposition
The USPTO has published the trademark application for 'JOINT AND JOINT' for health food supplements, initiating a 30-day opposition period. The application was filed on March 24, 2026, and published for opposition on March 25, 2026.
KYNTO Trademark Published for Opposition
The USPTO has published the KYNTO trademark application for opposition, related to dietary supplements. The application was filed on March 24, 2026, and the publication date for opposition is March 25, 2026. This marks a step in the trademark registration process.
NOURISHA intent to use trademark application details
The USPTO has recorded an intent-to-use trademark application (TM99692572) for the mark 'NOURISHA'. The application covers a range of pharmaceutical and food-related products, including milk-based nutritional supplements and dietetic preparations. The filing date for this application was March 10, 2026.
NALIRFAL Trademark Application Published for Opposition
The USPTO has published the trademark application for NALIRFAL, which includes a variety of dietary and nutritional supplements. The application was published for opposition on March 25, 2026, with a filing date of March 24, 2026. This publication initiates a period during which other parties may oppose the trademark registration.
VALISSE intent to use trademark application filed
The United States Patent and Trademark Office (USPTO) has received an intent-to-use trademark application for the mark 'VALISSE'. The application, filed on March 24, 2026, covers health food supplements, dietary supplements, herbal supplements, and vitamin and mineral supplements.
JUVONA intent to use trademark application filed
The USPTO has received an intent-to-use trademark application for the mark 'JUVONA' filed on March 25, 2026. The application covers goods including dietary supplements, nutritional supplements, and nutraceuticals for human consumption.
ASTANEURO Trademark Application Published for Opposition
The USPTO has published the trademark application for ASTANEURO, filed on March 24, 2026, for opposition. This notice indicates the application is now open for challenges from other parties before it can be registered.
ELTHYSIA Trademark Application - Intent to Use
The USPTO has recorded an intent-to-use trademark application for the mark 'ELTHYSIA'. The application covers a wide range of products including vitamins, dietary supplements, and pet supplements. The filing date for this application was March 24, 2026.
BIOTHRIVE Trademark Application - Intent to Use
The USPTO has received an intent-to-use trademark application for the mark 'BIOTHRIVE' filed on March 24, 2026. The application covers health food supplements, dietary supplements, herbal supplements, and vitamin and mineral supplements.
VERIXA trademark application published for opposition
The USPTO has published the trademark application for 'VERIXA' for opposition. The application covers insect repellents, insecticides, and rodenticides. The filing date was March 24, 2026, and the publication date is March 25, 2026.
HEALTHYBLOOD Trademark Published for Opposition
The USPTO has published the HEALTHYBLOOD trademark application for opposition. The application covers various types of nutritional and dietary supplements. The publication date was March 25, 2026, with a filing date of March 24, 2026.
Methods for Separating Chelator from Mixture Using Chromatography
The USPTO has published a new patent application, US20260085108A1, detailing methods for separating a chelator from a mixture using chromatography. This application, filed on September 8, 2023, by inventors Jason Huang and Qiang Li, describes techniques useful in adjusting the concentration of chelators in protein compositions.
Ginkgo Bioworks Patent for Protein Production and Secretion Systems
The USPTO has published a new patent application (US20260085107A1) filed by Ginkgo Bioworks, Inc. The patent describes expression systems for enhanced production and secretion of proteins, including specific examples like bovine lactoferrin. This application is part of the ongoing patent process for novel biotechnological methods.