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Patent Application: Cancer Treatment Compositions and Methods

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Published July 16th, 2025
Detected March 26th, 2026
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Summary

The USPTO has published a new patent application (US20260085120A1) for compositions and methods related to cancer treatment. The application describes binding agents, carrier proteins, and therapeutic agents, particularly for cancers expressing PD-LI or PD-L2, and lyophilized compositions.

What changed

This document is a publication of a patent application filed with the USPTO, specifically application US20260085120A1, titled 'Carrier-PD-L1 Binding Agent Compositions for Treating Cancers.' The application details compositions involving binding agents and carrier proteins, optionally with therapeutic agents, and methods for their use in treating cancers. It also describes lyophilized compositions and methods for treating cancers by administering a nanoparticle composition and a PD-1 immunotherapy to patients whose cancer expresses PD-LI or PD-L2.

As this is a patent application, it does not impose immediate regulatory obligations or compliance deadlines on entities. However, it signals potential future intellectual property and market exclusivity for novel cancer treatments. Companies in the pharmaceutical and biotechnology sectors should monitor the progress of this application and similar filings for insights into emerging therapeutic technologies and potential licensing or competitive landscapes.

Source document (simplified)

← USPTO Patent Applications

Carrier-PD-L1 Binding Agent Compositions for Treating Cancers

Application US20260085120A1 Kind: A1 Mar 26, 2026

Inventors

Svetomir N. Markovic, Wendy K. Nevala

Abstract

Described herein are compositions of binding agents and carrier proteins, and optionally at least one therapeutic agent, and methods of making and using the same, in particular, as a cancer therapeutic. Also described are lyophilized compositions of binding agents and carrier proteins, and optionally at least one therapeutic agent, and methods of making and using the same, in particular, as a cancer therapeutic. Still also described are methods for treating and/or increasing the therapeutic effectiveness of an immunotherapy of a patient suffering from a cancer which expresses PD-LI or PD-L2 by administering to the patient a nanoparticle composition and a PD-I immunotherapy.

CPC Classifications

C07K 16/2818 A61K 9/19 A61K 9/51 A61K 31/337 A61K 39/39558 A61K 45/06 A61P 35/00 C07K 16/2827 A61K 2039/505

Filing Date

2025-07-16

Application No.

19271543

View original document →

Named provisions

Abstract Inventors

Classification

Agency
USPTO
Published
July 16th, 2025
Instrument
Notice
Legal weight
Non-binding
Stage
Draft
Change scope
Minor
Document ID
US20260085120A1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Drug Development Cancer Therapeutics
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Compliance frameworks
FDA 21 CFR Part 11 GxP
Topics
Cancer Therapeutics Immunotherapy

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