CRISPR Methods Targeting CD70 Expression for Engineered Cells
Summary
The USPTO has published a patent application (US20260083861A1) filed by Editas Medicine, Inc. The application describes CRISPR-related systems and methods for targeting the CD70 gene expression in engineered cells, particularly T cells, for potential therapeutic applications.
What changed
This document is a published patent application from the USPTO, specifically application US20260083861A1, filed by Editas Medicine, Inc. The application details CRISPR-related systems and compositions designed to target and modulate the expression of the CD70 gene. These methods are intended for use in engineered cells, such as T cells or T cell precursors, suggesting potential applications in cell-based therapies and immunotherapies.
As this is a patent application, it does not impose immediate regulatory obligations or compliance deadlines on entities. However, it signifies ongoing innovation and potential future intellectual property developments in the field of gene editing and cell therapy. Companies operating in the biotechnology and pharmaceutical sectors, particularly those involved in CRISPR technology or CAR-T cell development, should monitor this and related patent filings for competitive intelligence and potential licensing opportunities.
Source document (simplified)
CRISPR-RELATED METHODS AND COMPOSITIONS TARGETING CD70 EXPRESSION
Application US20260083861A1 Kind: A1 Mar 26, 2026
Assignee
Editas Medicine, Inc.
Inventors
Aaron WILSON, Christopher Wilson
Abstract
The present disclosure relates to CRISPR-related systems and components for targeting, editing, and/or modulating expression of a CD70 (Cluster of Differentiation 70) gene. The present disclosure also relates to methods and applications thereof in connection with engineered cells including T cells or T cell precursors.
CPC Classifications
A61K 48/005 C12N 5/0636 C12N 9/226 C12N 15/111 C12N 15/85 C12N 2310/20 C12N 2510/00
Filing Date
2025-11-24
Application No.
19398790
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