Ginkgo Bioworks Patent for Protein Production and Secretion Systems

ChangeBridge: Patent Apps - Peptides (C07K)

Detected March 26th, 2026

Summary

The USPTO has published a new patent application (US20260085107A1) filed by Ginkgo Bioworks, Inc. The patent describes expression systems for enhanced production and secretion of proteins, including specific examples like bovine lactoferrin. This application is part of the ongoing patent process for novel biotechnological methods.

View original document View source feed page

What changed

This document is a publication of a new patent application filed by Ginkgo Bioworks, Inc. The application, US20260085107A1, details expression systems designed to improve the production and secretion of proteins of interest. Key features include the use of secretion signals and polynucleotides encoding chaperone proteins to enhance yields, with specific applications mentioned for producing proteins such as bovine lactoferrin, bovine lactoglobulin, and ovalbumin.

As this is a patent application publication, it does not impose immediate compliance obligations on regulated entities. However, it signifies potential future intellectual property developments in the biotechnology and pharmaceutical sectors. Companies involved in protein production or seeking to license related technologies should monitor the progress of this patent application and similar filings for competitive intelligence and potential licensing opportunities.

Source document (simplified)

← USPTO Patent Applications

PRODUCTION OF PROTEINS, INCLUDING SECRETED PROTEINS

Application US20260085107A1 Kind: A1 Mar 26, 2026

Assignee

Ginkgo Bioworks, Inc.

Inventors

Sudeep Agarwala, Ruchita Anil Chawla, Aaron Zev Berman, Ishaan Joshan Dev, Brett Philip Irwin, Roy Marella, Elzabeth Lauren Meier, Cameron Nowack, Nathan W. Schmidt, Sneha Srikrishnan

Abstract

This disclosure provides expression systems comprising secretion signals that promote production and/or secretion of proteins of interest, as well as one or more polynucleotides encoding chaperone proteins (e.g., CRT and/or PDIA3) which, as demonstrate herein, enhance production and/or secretion of proteins. Moreover, genetically modified host cells comprising these expression systems are capable of producing high levels of protein of interest, such as bovine lactoferrin (bLF), bovine lactoglobulin (bLG), or ovalbumin (Ova).