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Adenovirus Formulation with Citrate Buffer and Salt

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Published September 11th, 2023
Detected March 26th, 2026
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Summary

The USPTO has published a new patent application (US20260083670A1) for an adenovirus formulation. The formulation includes a recombinant adenovirus, citrate buffer, cyclodextrin compound, and salt, with a pH between 5.5 and 6.5, and is free of non-ionic detergent. The invention also covers a method for preserving adenoviruses using this formulation.

What changed

This document is a publication of a new patent application filed with the USPTO. It describes an improved adenovirus formulation comprising a recombinant adenovirus, a citrate buffer, a cyclodextrin compound, and a salt. Key characteristics include a pH range of 5.5 to 6.5 and the absence of non-ionic detergent. The application also claims a method for preserving adenoviruses using this specific formulation.

While this is a patent application and not a regulatory rule, it signals potential future developments in adenovirus-based therapeutics and preservation methods. Companies involved in the development or manufacturing of adenoviruses should be aware of this filing as it may impact future intellectual property landscapes and product development strategies in the pharmaceutical sector. No immediate compliance actions are required, but monitoring patent filings is crucial for R&D and legal teams.

Source document (simplified)

← USPTO Patent Applications

ADENOVIRUS FORMULATIONS

Application US20260083670A1 Kind: A1 Mar 26, 2026

Inventors

Tao PENG, Yuan Hao Lucas GOH

Abstract

An improved adenovirus formulation comprising: a) a recombinant adenovirus; b) a citrate buffer; c) a cyclodextrin compound; and d) a salt, said formulation having a pH ranging from about 5.5 to about 6.5, and wherein said formulation is free of non-ionic detergent. The invention also relates to a method of preserving an adenovirus which comprises preparing said formulation.

CPC Classifications

A61K 9/08 A61K 9/0019 A61K 35/761 A61K 47/02 A61K 47/10 A61K 47/12 A61K 47/40 C12N 2710/10343

Filing Date

2023-09-11

Application No.

19111190

View original document →

Named provisions

ADENOVIRUS FORMULATIONS

Classification

Agency
USPTO
Published
September 11th, 2023
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260083670A1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Formulation Drug Preservation
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Research & Development
Topics
Drug Development Intellectual Property

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