Healthcare & Life Sciences

Patent Granted: Occlusal Force Meter Cover

The USPTO has granted a patent (US12582495B2) to MURATA MANUFACTURING CO., LTD. for a cover for an occlusal force meter. The patent was granted on March 24, 2026, and includes specific material and design requirements for the cover.

Headrest for patient immobilization system

The USPTO has granted patent US12582497B2 for a headrest designed for patient immobilization systems. The headrest features a supporting structure with an elastic panel that conforms to the patient's head and neck shape, intended for use in medical applications.

Microscopic Work Manipulator Patent Grant

The USPTO has granted patent US12582494B2 for a microscopic work manipulator developed by F.MED CO., LTD. The patent describes a parallel link mechanism with linear actuators and a hydraulic drive for rotating an end effector, intended for precise manipulation in microscopic procedures.

Georgia Tech Granted Patent for Neurosurgical Microrobots

The United States Patent and Trademark Office has granted a patent to Georgia Tech Research Corporation for a novel microrobot designed for neurosurgical applications. The patent, filed in July 2022, describes a magnetic microrobot that can be inserted into a patient and manipulated externally.

Surgical instrument steering mechanism patent granted

The USPTO has granted a new patent (US12582493B2) for a surgical instrument steering mechanism developed by KARL STORZ SE & Co. KG. The patent covers a mechanism with two motorized drives designed to control the distal bending of surgical instruments. The filing date for this patent was July 25, 2022.

Verb Surgical Inc. Granted Patent for Surgical Robotic System Control

The USPTO has granted a patent (US12582491B2) to Verb Surgical Inc. for a novel control system for surgical instruments within robotic systems. The patent focuses on reducing backlash and improving precision through a specific actuator control method.

Real-time Image Guided Portable Robotic Intervention System Patent Granted

The USPTO has granted a patent (US12582490B2) to Mendaera, Inc. for a real-time image guided portable robotic intervention system. The patent covers an image-guided robotic intervention system (IGRIS) designed to provide real-time views of patient anatomy and assist in planning and executing medical procedures.

Surgical robot endoscope mounting system patent granted

Surgical robot endoscope mounting system patent granted

Bragg Grated Fiber Optic Fluctuation Sensing and Monitoring System

The USPTO has granted patent US12584807B2 for a Bragg grated fiber optic fluctuation sensing and monitoring system to Bard Access Systems, Inc. The patent covers a system designed to detect damage to optical fibers used in medical devices by analyzing reflected light signals for strain-induced fluctuations.

X-ray detector patent granted to RAYENCE Co., Ltd.

The USPTO has granted patent US12585033B2 for an X-ray detector to RAYENCE Co., Ltd. The patent, effective March 24, 2026, covers a flexible X-ray detector design with integrated flexible circuit units and a main circuit unit.

Patent US12585034B2: Electronic device with filter, scintillator, sensor

The USPTO has granted patent US12585034B2 to InnoCare Optoelectronics Corporation for an electronic device. The patent covers an electronic device comprising a scintillator layer, a sensor with distinct sensing units, and a filter with filter units of varying thicknesses. This grant is effective March 24, 2026.

Patent US12586453B2: Radar, Camera, Mic System for Life Sign Monitoring

The USPTO has granted patent US12586453B2 to Innovative Health Monitoring LLC for a system and method to monitor a person's life signs using radar, camera, and microphone signals. The patent, effective March 24, 2026, aims to detect breathing or lack thereof and generate an alarm if no movement or breathing is detected for a selected period.

Patent Grant for Memory Enhancement via EEG

The USPTO has granted patent US12586479B2 for an apparatus and method for memory enhancement based on electroencephalogram (EEG). The patent, assigned to KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, aims to improve memory by identifying forgotten items during retrieval and providing personalized repetitive learning based on brain signals.

USPTO Patent Grant for Medical Imaging Systems

The USPTO has granted patent US12586196B2 to SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD. for methods and systems for medical imaging. The patent covers techniques for generating images based on radiation events, incorporating both time-sensitive and non-time-sensitive response information.

Blood Flow Extraction Image Forming Device Patent

The USPTO has granted patent US12586185B2 to FUJIFILM Corporation for a blood flow extraction image forming device. The patent details a method for creating images that distinguish blood flow from tissue components, utilizing correlation matrix calculations and singular value decomposition.

Patent Grant: Image Processing, Diagnostic, Blood Pressure Monitor

The USPTO has granted a new patent (US12586191B2) to Canon Medical Systems Corporation for an image processing apparatus, medical image diagnostic apparatus, and blood pressure monitor. The patent, effective March 24, 2026, relates to specifying and displaying the acquisition position of blood flow indicators on medical images.

X-ray CT Apparatus and Method Patent Granted

The USPTO has granted a patent (US12586275B2) to Canon Medical Systems Corporation for an X-ray CT apparatus and method. The patent, effective March 24, 2026, relates to a photon counting detector and processing circuitry for determining scan transitions based on contrast agent presence.

Sony Olympus Patent for Photoelectric Module and Camera Head

The USPTO has granted a new patent (US12587727B2) to Sony Olympus Medical Solutions Inc. for a photoelectric composite module, camera head, and endoscopic device. The patent details specific technical components and their arrangement for use in medical imaging.

Patent Grant for Scanning Object in Apparatus

The USPTO has granted patent US12584868B2 to Rolls-Royce PLC for a method of scanning an object within a scanning apparatus. The patent describes a specific method for placing an object into a jacket filled with material and scanning it using rotatable imaging elements.

AI Histological Fingerprinting Patent Granted to Siemens Healthineers

The USPTO has granted patent US12584984B2 to Siemens Healthineers AG for an AI-powered histological fingerprinting system. This patent covers methods for using AI to analyze magnetic resonance imaging data to map tissue microstructure, enhancing diagnostic capabilities.

Patent Grant: Image Pickup Module, Endoscope, and Manufacturing Method

The USPTO has granted a patent (US12585104B2) to OLYMPUS MEDICAL SYSTEMS CORP. for an image pickup module, endoscope, and manufacturing method. The patent details specific technical configurations for an image pickup module designed for use in endoscopes, focusing on resin application within its components.

X-ray aiming ring apparatus with connector and beam channel

The USPTO has granted patent US12585180B1 for an X-ray aiming ring apparatus. This patent, effective March 24, 2026, describes a device designed to improve the accuracy of X-ray machine positioning for diagnostic and surgical procedures.

Anti-vibration damping system for carbon fiber C-arm patent granted

The USPTO has granted a patent (US12584536B2) to GE Precision Healthcare LLC for an anti-vibration damping system for carbon fiber C-arms used in mobile X-ray imaging systems. The patent, effective March 24, 2026, aims to reduce vibrations during rotational movements of the C-arm.

Patent for Multi-User Device Activity Tracking

The USPTO has granted Motorola Mobility LLC a patent (US12582871B2) for techniques enabling multi-user activity tracking on a single device. This patent covers methods for detecting user device possession changes and tracking individual physical activity logs.

Patent: AI optimizes vehicle settings based on occupant state

The USPTO has granted a patent to Toyota Motor North America, Inc. for an AI system that optimizes vehicle settings based on occupant state and time of day. This patent covers the use of AI to adjust vehicle systems to enhance occupant comfort and condition.

Patent for ultrasound BBB opening using physiologic signals

The USPTO has granted patent US12582849B2 to Cordance Medical Inc. for a device, method, and system to determine blood-brain barrier (BBB) opening or increased permeability during ultrasound procedures using physiologic signals. The patent was filed on November 14, 2024, and issued on March 24, 2026.

Mesoporous Nano-Magnesium Oxide for Drug Loading

The USPTO has published a patent application for a mesoporous nano-magnesium oxide material designed for drug loading. The application details the material's properties, including particle size and pore structure, and outlines a preparation method involving magnesium oxalate and CTAB.

Protein Nanospheres for Treating Chemotherapy Dysfunction

The USPTO has published a patent application (US20260083683A1) for protein nanospheres designed to treat dysfunction caused by chemotherapy and immunosuppressive therapy. The application details the manufacture and use of fibrinogen-coated albumin spheres (FAS) and High-Fibrinogen Spheres (HFS) for mitigating toxic effects of cancer treatments.

High-Bioactivity Goat Colostrum Powder Preparation Method

The USPTO has published a patent application detailing a method for preparing a high-bioactivity goat colostrum composite freeze-dried powder. The invention focuses on enhancing the stability and survival rate of probiotics within the powder through encapsulation techniques.

Oxazolidinone Liposome Compositions with Improved Storage Stability

The USPTO has published a new patent application from Akagera Medicines, Inc. detailing oxazolidinone liposome compositions designed for improved storage stability. The application, filed on December 2, 2025, describes methods for manufacturing and using these compositions.

Patent for Spray-Dried Amorphous Solid Dispersions Using Polyvinyl Alcohol

The USPTO has published a new patent application (US20260083676A1) detailing a method for preparing spray-dried amorphous solid dispersions of active pharmaceutical ingredients using polyvinyl alcohol. The application was filed on September 14, 2023, by inventors Lena Mueller, Laura Halstenberg, Thomas Kipping, and Nicole Di Gallo.

Adagrasib Solid Pharmaceutical Compositions for Treating Cancer

The USPTO has published a new patent application (US20260083679A1) detailing solid pharmaceutical compositions containing adagrasib for treating cancer. The application, filed on December 3, 2025, includes methods for manufacturing these compositions and treating cancer.

Kit for Drug-Containing Nanoparticles and Composition for Drug Delivery

The USPTO has published a new patent application (US20260083682A1) by SAMYANG HOLDINGS CORPORATION for a kit and composition for constructing drug-containing nanoparticles for enhanced drug delivery. The application details a method utilizing cationic compounds and anionic polymers to improve cellular drug delivery efficiency.

Patent Application: Solid Medicinal Forms with Stabilised Active Ingredient

The USPTO has published a new patent application (US20260083677A1) from Astellas Pharma Inc. The application describes solid medicinal forms containing active ingredients stabilized with specific drying agents, aiming for reduced moisture content. This is a new patent filing, not a regulatory rule or guidance.

Sunscreen Compositions and Methods of Use

The USPTO has published a patent application from Mary Kay Inc. detailing new sunscreen compositions designed to protect skin from UV radiation. The application describes specific formulations involving film formers and organic UV filters, along with methods of making and using these compositions.

KAO CORPORATION patent for hair treatment agent

The USPTO has published a patent application by KAO CORPORATION for a hair treatment agent. The application, filed on May 31, 2023, details a specific formulation involving film-forming polymers and organopolysiloxanes.

Oral GLP-1 Compound Dosing Patent Application

The USPTO has published a patent application (US20260083678A1) related to oral dosing of GLP-1 compounds. The application was filed on December 3, 2025, by inventors Flemming S. Nielsen and Per Sauerberg, and relates to improved uses of GLP-1 peptides in oral therapy.

Cannabis Products and Methods Patent Application

The USPTO has published a patent application (US20260083661A1) for cannabis-based products and methods, including lotions, soaps, perfumes, and teas. The application was filed on October 7, 2025, and lists Lawrence Lanier Long as the inventor.

Patent Application: Spray Dried Lipid Nanoparticle Formulations

The USPTO has published a patent application (US20260083681A1) detailing formulations for spray-dried lipid nanoparticle matrix particles. The application, filed on September 16, 2025, describes a composition including lipid nanoparticles, a buffer system, and a barrier matrix stabilizer. This publication is part of the patent application process and does not represent a final grant or regulatory requirement.

Anti-GPRC5D Antibody for Cancer Treatment

The USPTO has published a patent application (US20260085114A1) filed by Kyinno Biotechnology Co., Ltd. The application describes an anti-G protein-coupled receptor family class C group 5 member D (GPRC5D) antibody or fragment thereof for the treatment of tumors or cancers. It also details a bispecific antibody targeting GPRC5D and CD3.

Process for Isolating Osteopontin and Glycomacropeptide from Whey

The USPTO has published a new patent application (US20260085099A1) detailing a process for isolating osteopontin (OPN) and glycomacropeptide (GMP) from whey. The application, filed on September 15, 2023, describes a chromatography-based method for purification.

Patent Application: Method for Acute Respiratory Distress Syndrome Treatment

The USPTO has published a new patent application (US20260085098A1) from Revolo Biotherapeutics Limited for a method to treat acute respiratory distress syndrome. The application details a treatment method involving the administration of a specific peptide molecule during or in response to a relapse to induce remission.

DARPIN Compositions for Treating Shiga Toxin Diseases

The USPTO has published a patent application (US20260085097A1) detailing DARPIN-containing compositions for treating Shiga toxin diseases. The application highlights the thermostability and high microbial expression yield of DARPin as advantages over antibody therapeutics.

Patent Application: Detecting Pancreatic Cancer

The USPTO has published a patent application (US20260085360A1) detailing methods for detecting pancreatic cancer. The application describes a method involving measuring CA19-9 levels alongside other markers like OPN, MIA, and CEACAM-1 in a subject's sample.

Patent Application: Cancer Treatment Compositions and Methods

The USPTO has published a new patent application (US20260085120A1) for compositions and methods related to cancer treatment. The application describes binding agents, carrier proteins, and therapeutic agents, particularly for cancers expressing PD-LI or PD-L2, and lyophilized compositions.

Patent Application for Treating Cancer with Anti-CTLA4 Antibodies

The USPTO has published a new patent application (US20260085119A1) from ADAGENE PTE. LTD. for methods of treating cancers using anti-CTLA4 antibodies. The application details compositions and treatment methods, including combination therapies for cancers resistant to PD-1 or PD-L1 inhibitors.

Anti-CTLA-4 Antibody Conjugate Activated by Tumor Microenvironment

The USPTO has published a patent application (US20260085118A1) for a novel conjugate of an anti-CTLA-4 antibody activated by the tumor microenvironment. The application details a dual-activated conjugate designed to improve targeting efficacy, overcome drug resistance, and reduce toxicity.

Antibodies with chimeric constant domains reduce effector functions

The USPTO has published a patent application (US20260085117A1) detailing antibodies with chimeric constant domains designed to reduce effector functions. The application, filed on November 24, 2025, describes recombinant polypeptides and methods for their production.

Patent Application: Antibody Heavy Chain Regions Reduce Fc Gamma Receptor Binding

The USPTO has published a patent application (US20260085116A1) detailing antibody heavy chain constant regions modified to reduce binding to Fc gamma receptors. This modification, achieved through specific residue replacements or deletions in the hinge region, aims to decrease effector functions in antibodies and Fc fusion proteins.

CD3 Binding Antibodies Patent Application Inventors Listed

The USPTO has published a new patent application, US20260085115A1, related to CD3 binding antibodies. The application, filed on June 2, 2025, lists inventors Nathan Trinklein, Wim van Schooten, Shelley Force Aldred, Katherine Harris, and Duy Pham.