Combination of KDM6B Inhibitor and Immune Checkpoint Blockade Therapy for Use in a Method of Treating Glioblastoma
The European Patent Office published patent application EP4149512A1 on April 8, 2026. The patent covers a combination therapy using KDM6B inhibitors with immune checkpoint blockade for treating glioblastoma. Applicants are the Board of Regents, The University of Texas System, with inventors including Goswami, Sharma, and Allison.
Shiseido Granted Patent for Skin Composition Formulations and Methods
USPTO granted Patent US12599623B2 to Shiseido Company, Limited on April 14, 2026. The patent covers body corrective cosmetic formulations and methods of use thereof, including skin treatment compositions. The application was filed on June 29, 2017 under Application No. 15638059 with 13 claims.
One Measles Case Confirmed in Maryland Resident with Recent International Travel
The Maryland Department of Health announced one confirmed case of measles in a Baltimore metro area resident with recent international travel. Health officials have identified potential exposure locations including Baltimore/Washington International Thurgood Marshall Airport, FastMed Urgent Care in Baltimore, and Sinai Hospital's emergency department. Marylanders who visited these locations during specified times are advised to monitor for symptoms for 21 days and verify their MMR vaccination status.
First Measles Case of 2026 Confirmed in Providence County
The Rhode Island Department of Health has confirmed the first measles case of 2026 in Providence County. Health officials are notifying the public and monitoring the situation for potential exposures. This announcement serves as a public health notification regarding the confirmed case.
Integrated Preparedness Plan Workshop - Noblesville, April 20, 2026
Indiana Department of Health announces an Integrated Preparedness Plan Workshop on April 20, 2026, from 10:00am to 2:00pm EDT at Riverview Health in Noblesville, IN. The workshop objectives include validating preparedness priorities based on Joint Risk Assessment and Hazard Vulnerability Assessment results, identifying capability gaps using After Action Reports and Public Health Hazard Risk Assessment data, and incorporating lessons learned from real-world events. Intended audience includes Local Health Department Preparedness Coordinators, Healthcare Coalition Readiness and Response Coordinators, and other preparedness organizations.
Image Processing Device and Image Processing Method
The European Patent Office published Panasonic Intellectual Property Management Co., Ltd.'s patent application EP4113436A1 for an image processing device and method for diagnosis and surgery. The patent covers image processing technology with applications in medical diagnosis (A61B) and was published on April 8, 2026. Inventors include Saito, Hamasaki, Kanamori, and Iwase.
Systems for Computer-Assisted Shape Measurements in Video (EP4135567A1)
The European Patent Office published patent application EP4135567A1 for Kaliber Labs Inc., covering computer-assisted systems and methods for performing shape measurements in video data. The patent application relates to medical imaging technologies including ultrasound, X-ray, MRI, and video-based analysis for surgical and diagnostic applications. The patent was published under the A1 publication type on April 8, 2026.
METHOD AND SYSTEM FOR MODELING PREDICTIVE OUTCOMES OF ARTHROPLASTY SURGICAL PROCEDURES
The European Patent Office published patent application EP4135620A1 for Exactech, Inc., covering a method and system for modeling predictive outcomes of arthroplasty surgical procedures. The A1 publication includes the search report and is now publicly available across all designated EU member states. The patent protects predictive modeling technology for orthopedic joint replacement planning.
Implant Delivery Handle, Catheter Assembly, and Conveying System
The European Patent Office published patent application EP4098207A1 for Shanghai Microport Cardioflow Medtech Co., Ltd., covering an implant delivery handle, catheter assembly, and conveying system for use in cardiac procedures. The patent was published April 8, 2026 and includes IPC classifications A61B 17/00, A61F 2/95, and A61F 2/24. The designation states cover 34 European countries including Germany, France, the United Kingdom, Italy, Spain, and other EU member states.
Dynamic Flash Adjustment Based on Retinal Pigmentation (EP4120888A1)
The European Patent Office published patent application EP4120888A1, filed by Digital Diagnostics Inc., covering a system and method for dynamically adjusting flash intensity in retinal imaging devices based on individual retinal pigmentation. The invention aims to improve image quality and patient comfort during fundus photography by adapting illumination to varying levels of ocular pigmentation. The patent application names Warren James Clarida, Ryan Earl Rohret Amelon, Abhay Shah, Jacob Patrick Suther, Meindert Niemeijer, and Michael David Abramoff as inventors.
Protective Device for Use in Surgery Applications (EP4132408A1)
The European Patent Office published patent application EP4132408A1 for Relmat Pty Ltd titled 'Protective Device for Use in Surgery Applications.' The invention relates to protective devices for surgical procedures and has been classified under IPC category A61B (Diagnosis & Surgery). The patent designates multiple European member states including Germany, France, the United Kingdom, and Italy.
EP4347847A1 - Flexible Expression Vector Systems for Vaccines and Immunotherapeutics
The European Patent Office granted patent EP4347847A1 to The University of British Columbia and The James Hutton Institute. The patent covers flexible expression vector systems and their applications in vaccines and immunotherapeutics, with inventors Jefferies and Ribeca. The patent is designated across 31 European member states.
Lyophilized ENPP1 Polypeptide Formulations and Uses Thereof
The European Patent Office published patent application EP4404980A1 for BioMarin Pharmaceutical Inc., covering lyophilized ENPP1 polypeptide formulations and their therapeutic uses. The patent application was filed with multiple IPC classifications including A61K (pharmaceutical preparations), C12N (enzymes/nucleic acids), and C07K (peptides). The application designates all European member states.
Selective Targeting of Host CD70+ Alloreactive Cells to Prolong Allogeneic CAR T Cell Persistence
The European Patent Office published patent application EP4355358A1 on April 8, 2026, filed by Allogene Therapeutics, Inc. The invention covers methods for selectively targeting host CD70+ alloreactive cells to enhance persistence of allogeneic CAR-T cells for therapeutic use. The patent is designated across multiple European member states including Germany, France, and the United Kingdom.
EP4301859A1 - Enhanced Targeting Using Antibody-Oligonucleotide Conjugates
The European Patent Office has published patent application EP4301859A1 for Code Biotherapeutics, Inc. and University of Maryland, College Park, covering enhanced targeting technology using antibody-oligonucleotide conjugates. The patent application was published on April 8, 2026, with inventors Muro, Roki, and Getts. Designated states include all EU contracting states for potential validation.
Lipid Nanoparticle Stem Cell Therapeutics - European Patent EP4330391A1
The European Patent Office granted Patent EP4330391A1 to the Trustees of the University of Pennsylvania for compositions and methods targeting lipid nanoparticle therapeutics to stem cells. The patent covers IPC classifications including A61K 47/69, A61K 47/68, A61K 9/51, C12N 15/88, and A61K 48/00. The patent is valid in 35 designated European member states including Germany, France, the United Kingdom, Italy, and Spain.
Engineered CasX Repressor Systems, EP4405479A2
The European Patent Office published application EP4405479A2 for Engineered CasX Repressor Systems filed by Scribe Therapeutics Inc. The patent covers engineered CasX proteins with repressive functionality for gene expression control. The application has been published designating 31 European states including major markets DE, FR, GB, NL, SE, and CH.
AstraZeneca Complement C3 Inhibitor Patent Application EP4326876A1
The European Patent Office published AstraZeneca patent application EP4326876A1 for compositions and methods inhibiting complement component 3 expression. The application names AstraZeneca Ireland Limited as applicant with inventors including Lasaro, Melissa and McKnight, Susan. Designated states cover all EPC contracting states including Germany, France, UK, Italy, Spain, and others.
University of Washington Muscle Gene Regulatory Cassettes Patent Application EP4319874A2
The European Patent Office published patent application EP4319874A2 for University of Washington covering artificial regulatory cassettes for muscle-specific gene expression. The application names inventors Jeffrey S. Chamberlain and Stephen D. Hauschka. The patent is classified under IPC codes related to genetic engineering and pharmaceutical preparations for muscular disorders.
Mitochondria-Enriched Cell Identification, EP4281579A1
The European Patent Office published patent application EP4281579A1, filed by Minovia Therapeutics Ltd., covering methods for identifying mitochondria-enriched cells. The application designates 39 states including all EU member states plus CH, LI, MC, TR, and GB. The invention relates to C12N cell classification and G01N detection methods with applications in cell therapy.
RNA-Based Control of Powdery Mildew - Greenlight Biosciences EP4304353A2
EPO published patent application EP4304353A2 by Greenlight Biosciences Inc. for RNA-based control of powdery mildew, a fungal disease affecting plants. The application covers double-stranded RNA compositions and methods for controlling fungal pathogens in agriculture. The patent designation extends across 38 European member states including Germany, France, and the United Kingdom.
Tumor Infiltrating Lymphocytes Therapy
The European Patent Office published patent application EP4329782A1 for Alethia Biotherapeutics ULC covering tumor infiltrating lymphocytes (TIL) therapy for cancer treatment. The application includes 17 IPC classifications including cell compositions, antibodies, and combination therapies. The patent designates 35 European states including Germany, France, UK, Italy, Spain, and the Netherlands.
Antisense Oligomer EP4342498A1, Chiba University, published 8th Apr
The European Patent Office published patent application EP4342498A1 for an antisense oligomer therapeutic developed by National University Corporation Chiba University. The patent covers antisense oligomer compositions, gene therapy vectors, and pharmaceutical formulations with therapeutic applications in cardiovascular, metabolic, dermatological, and other disease areas. The granted rights apply across the designated Contracting States including EU member states, CH, GB, NO, TR, and others.
Rehabilitation Exercise Recommendation via Digital Image Recognition
The European Patent Office published patent application EP2024053989A1 for His Cares Inc., covering a system and method for recommending rehabilitation exercises using digital image recognition to detect a patient's living environment. The patent classifies under G16H (Health Informatics) and A61B (Measuring/Diagnosing). The designation covers 31 European states including Germany, France, the UK, Italy, and Spain.
Pulmonary Disease Therapy Planning Methods and Systems - Apreo Health
The European Patent Office granted patent EP4643348A1 to Apreo Health, Inc. on April 8, 2026. The patent covers methods and systems for planning, predicting, and monitoring therapies for pulmonary diseases, incorporating health informatics (G16H), medical imaging (A61B), AI/ML (G06N), and therapy monitoring technologies. The patent is designated for all EU member states and EPO contracting states.
Vagus Nerve Stimulation Device Adjusting Stimulation Based on Biological Signals and User Sensitivity
The European Patent Office published patent application EP4506030A1 for a vagus nerve stimulation device that automatically adjusts stimulation parameters based on the user's biological signals and individual sensitivity thresholds. The patent, filed by South Korea-based Neurive Co., Ltd., covers systems for personalized neurostimulation therapy across EPO-designated European member states.
Psychological Analysis Method Based on Image Generation Process
The European Patent Office published European Patent application EP2024071678A1 for a psychological analysis method based on an image generation process. The patent grants intellectual property rights to Bax Intelligence Inc for the designated states across 38 European countries. The IPC classifications indicate applications in medical measurement (A61B 5/16, A61B 5/00), health informatics (G16H 10/20), and therapeutic interventions (G16H 20/70).
Surgery Assistance Program, Device, Method - Keio University
The European Patent Office granted Keio University patent EP4585179A1 for surgery assistance programs, devices, and methods incorporating AI/ML components for computer-assisted surgical procedures. The patent application was published April 8, 2026, with inventors including Masashi Takeuchi, and covers 15 IPC classifications spanning AI/ML systems and surgical guidance technologies.
Automatic Fibrillation Classification and Identification of Fibrillation Epochs
The European Patent Office published patent application EP4577117A1 for Vektor Medical, Inc., covering an automated system for classifying and identifying cardiac fibrillation epochs using signal processing and machine learning techniques applied to ECG data. The patent application includes inventors David Marton, Christian Villongco, and Christopher J.T. with IPC classifications in medical diagnostic computing (G16H) and cardiac monitoring (A61B).
Meeting Agenda - March 19, 2026
The North Dakota State Board of Pharmacy has published its meeting agenda for March 19, 2026. The meeting covers pharmacy licensing and remodel requests (CVS Pharmacy Fargo, Keycare Pharmacy Minot, Sanford South University), telepharmacy expansion (Thrifty White Drug Cavalier), a disciplinary stipulation (RPh6566), foreign pharmacy internship review, and discussion of inspection cycles, a potential special legislative session, 340B lawsuits, and the NABP Annual Meeting.
Pharmacist Licensure Examination Notice May NDSU Fargo Deadline April 24
The North Dakota State Board of Pharmacy has issued notice of its May pharmacist licensure examination to be held at NDSU College of Pharmacy in Fargo. Candidates must submit applications by April 24. The examination consists of errors and omissions, oral examination, and operative examination components, in addition to NAPLEX and MPJE exams administered by NABP.
EPA Draft Sixth CCL Covers PFAS, Microplastics, Pharmaceuticals
The EPA published its draft Sixth Contaminant Candidate List (CCL) in the Federal Register, listing 75 individual chemicals, 9 microbes, and 4 chemical groups including disinfection byproducts, microplastics, PFAS, and pharmaceuticals not yet subject to national drinking water regulations. The comment period closes June 5, 2026.
Prescription Drug Pricing and Adjudication System
USPTO granted Patent US12603165B2 to Rescription, Inc. covering methods and systems for adjudicating prescription drug claims, performing price searches, and conducting 340B eligibility analyses. The patent includes 12 claims and was filed on September 19, 2024. The system enables tracking of prescription and refill information with automated patient notifications about better pricing at different pharmacies.
Control Apparatus and Medical Centralized Control System - US12603164B2
USPTO granted patent US12603164B2 to Olympus Corporation on April 14, 2026, covering a control apparatus and medical centralized control system with 15 claims. The patent relates to data log management for controlled medical devices with assigned personnel information for surgical procedures. CPC classifications indicate health informatics applications in medical device control systems.
Longitudinal Non-Conforming Medical Data Records Composite System
USPTO granted Patent US12603161B1 to IQVIA INC. covering a computer-assisted method for generating composite healthcare records by aggregating data from multiple sources. The patent enables creation of individual patient records combining pharmaceutical transactions and medical visits over a defined time period. The patent claims priority to Application No. 18189498 filed March 24, 2023, with 22 total claims.
Pharmacy Surveillance and Intervention System for Monitoring, Detecting and Preventing Narcotic Abuse
USPTO granted patent US12603166B2 to OneSource Solutions International, Inc. The patent covers an AI-powered pharmacy surveillance system that integrates real-time prescription records, refill timelines, prescriber data, and patient histories to detect prescription abuse, dosage escalation, and refill velocity anomalies. The system routes structured alerts to pharmacists and regulatory personnel through a secure, role-authenticated interface, with transactions captured by a Medical Data Governance layer using cryptographic sealing and blockchain-based immutable ledger storage.
Secure Verification of Medical Status Using Contactless Card
USPTO granted Patent US12603163B2 to Capital One Services, LLC for a system enabling secure verification of medical immunity status using a contactless card. The system receives a cryptogram from a contactless card, validates digital signatures on medical attestations via server-side decryption, and outputs verification that a subject is immune to a specified medical condition.
VIAVI Solutions Medication Verification System Using Spectrometry
USPTO granted patent US12603167B2 to VIAVI Solutions Inc. on April 14, 2026. The patent covers a medication assurance system that uses a portable spectrometer to obtain light spectra of medications and performs chemometric analysis to identify medications. The system also incorporates biometric patient identification to verify medication appropriateness for individual patients.
Automated Medical AI Training Data Generation Patent US12603176B2
USPTO granted patent US12603176B2 to SMART REPORTING GMBH covering a computer-implemented method, system, and computer program product for automatically generating medical training data to train AI algorithms supporting clinical reporting and documentation. The invention receives medical image data, generates or edits findings reports with machine-readable elements, automatically assigns semantic content to unique identifiers, and annotates image data by linking image elements to findings report identifiers for storage as AI training data.
BOE Intelligent Triage Patents Patient-Doctor Matching System
USPTO granted patent US12603169B2 to BOE TECHNOLOGY GROUP CO., LTD. on April 14, 2026. The patent covers an intelligent triage method using disease information vectorization and a matching degree calculation model to recommend doctors to outpatients. The system analyzes patient disease vectors against doctor vectors extracted from a doctor knowledge graph to calculate matching degrees for patient-doctor recommendations.
Bayer Healthcare LLC QR Code Injection System Patent US12603168B2
USPTO granted Bayer Healthcare LLC Patent US12603168B2 for a system that generates and displays QR codes associated with injection systems. The patent (9 claims, filed May 17, 2021) covers processors programmed to receive injection system data, encode it into network resources, and display QR codes on the injection device display screen. Inventors include Steven Murphy, Dana Horn, Kumar Gautam, Kumar Navaneethan, and Swaminathan Balasubramaniam.
Non-Skilled User Ultrasound Imaging System and Method
USPTO granted Patent US12603172B2 to Pulsenmore Ltd. on April 14, 2026, for a system enabling non-skilled users to acquire ultrasound images of internal organs. The system includes a scanner with inertial measurement unit, processor with software, and user interface providing real-time guidance on positioning, pressure, and movement to obtain diagnostic-quality images.
US12603160B2: Mobile Cloud App QR Immune Score
USPTO granted Patent US12603160B2 to Andrew Brooks for a system and method enabling mobile cloud-based assessment of immune status related to transmissible infectious diseases. The system uses QR code scanning to access user health records including immunization data, test results, and pre-existing conditions, displaying verified immunity scores on venue devices. The patent covers 15 claims under CPC classifications G16H 10/60, G16H 40/67, and G06K 19/06037.
Piperidinyl Aryloxy Propanamides and Propanoates Patent EP3759094A1
The European Patent Office published patent application EP3759094A1 for Takeda Pharmaceutical Company Limited covering piperidinyl-3-(aryloxy)propanamides and propanoates compounds. The patent application includes therapeutic indications for depression (A61P 25/24), CNS disorders (A61P 25/28), and psychiatric disorders (A61P 25/18). The application designates multiple European states including Germany, France, United Kingdom, Italy, Spain, and others.
Novel Compounds - Inflazome Limited EP3759102A1
The European Patent Office published patent application EP3759102A1 for Inflazome Limited, titled 'Novel Compounds.' The patent covers heterocyclic compounds classified under C07D with pharmaceutical applications (A61K, A61P). The application designates all EU member states plus several additional European countries.
Solid Form Composition for Use in Treatment of Extraoesophageal Symptoms of Gastric Reflux
The European Patent Office published patent application EP3752202A1 filed by Drugs Minerals and Generics Italia S.R.L. for a solid dosage form composition intended for treating extraoesophageal symptoms of gastric reflux. The application, filed with inventor Luigi Mercuri, designates multiple EU member states including DE, FR, GB, IT, ES, NL, and 24 others. This publication establishes a priority date for the claimed pharmaceutical composition.
Base-Modified Cytidine Nucleotides for Leukemia Therapy (EP3810140A1)
The European Patent Office published patent application EP3810140A1 for Medivir Aktiebolag covering base-modified cytidine nucleotides for leukemia therapy. The application includes IPC classifications for A61K 31/506 (pyrimidine derivatives), C07D 405/04 (heterocyclic compounds), and A61P 35/02 (antineoplastic agents). The patent designates all EPO member states including AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR.
Mature Virus-Like Particles of Flaviviruses Vaccine
The EPO published patent application EP3976768A1, filed by Chiang Mai University and NSTDA, covering mature virus-like particles (VLPs) of flaviviruses for use as vaccines. The invention relates to the production of immunogenic VLP compositions and methods for preventing flavivirus infections. The patent designates 33 European states including major markets such as DE, FR, GB, IT, and ES.
Pfizer CD70 CAR Chimeric Antigen Receptor Patent Application EP3746483A1
The European Patent Office published Pfizer Inc.'s patent application EP3746483A1 for chimeric antigen receptors targeting CD70. The application (A1 publication with European search report) covers compositions and methods for CD70-targeting CARs with 11 named inventors including Srivatsa Srinivasan and Barbra Johnson Sasu. The application designates all EU member states plus other EPC contracting states.
Novel Pyrazole Compounds for Inflammatory Disease Treatment
The European Patent Office has published patent EP3759103A1, granting Inflazome Limited intellectual property protection for novel pyrazole-derived compounds. Inventors include David Miller, Jimmy Van Wiltenburg, and Matthew Cooper. The compounds are classified under A61K 31/415 with therapeutic applications targeting inflammatory diseases.
Turkish Sex Pain Questionnaire Validation for Chronic Pain Conditions
NIH registered observational study NCT07536672 on ClinicalTrials.gov to validate the Turkish version of the Sex Pain Questionnaire developed by Rafael Ballester-Arnal in 2022. The study evaluates sexual function problems in patients with chronic pain conditions including fibromyalgia, neck pain, and lower back pain. The questionnaire consists of 17 items across two factors measuring sexual dissatisfaction and the effect of chronic pain on sexual life. No regulatory obligations or compliance requirements are imposed by this registration.
GLP-2 (Teduglutide) Phase 2 Trial for Environmental Enteric Dysfunction in Undernourished Women, Dhaka
The NIH ClinicalTrials.gov registry published a Phase 2 clinical trial (NCT07537686) evaluating teduglutide (a GLP-2 analog) for treatment of environmental enteric dysfunction (EED) in 40 undernourished women aged 18-35 in Dhaka, Bangladesh. The randomized study will assess whether 30 days of daily subcutaneous teduglutide injections improve intestinal damage (via biopsy) and gut inflammation markers. icddr,b (Bangladesh) is a collaborating institution.