Healthcare & Life Sciences

Patent Application for Cell Manipulation Device and Method

The USPTO has published a new patent application (US20260086001A1) for a cell manipulation device and method. The application, filed on December 1, 2025, describes a technique for culturing cells by attaching them to an air bubble formed in a liquid flow path. This is a routine publication of a patent application.

Patent Application for mRNA Design

The USPTO has published patent application US20260088125A1 concerning methods for designing synthetic RNA molecules, specifically for mRNA design. The application details a process for obtaining coding sequences and selecting regions for synthetic RNA molecule production.

Method Predicts Prime Editing Efficiency in Different Cell Types

The USPTO has published a patent application (US20260088126A1) detailing a method and device for predicting prime editing efficiency in various cell types and prime editor types. The application, filed by Yonsei University, focuses on training predictive models for both on-target and off-target prime editing efficiency.

Delayed Harvest Methods for Short Stature Corn Plants

The USPTO has published a patent application (US20260083046A1) detailing methods for delayed harvesting of short stature corn plants. The application, filed on October 23, 2025, aims to provide growers with a flexible harvesting window to optimize drying or seed access without increasing yield loss risk.

Coffee Fermentation Using Pichia Kluyveri and Lactiplantibacillus Plantarum

The USPTO has published a patent application (US20260083149A1) from CHR. HANSEN A/S detailing a method for coffee fermentation using specific yeast and bacteria strains. The application focuses on improving coffee bean and beverage production through controlled fermentation processes.

Edible Aerial Mycelium Patent Application

The USPTO has published a patent application (US20260083160A1) filed on November 5, 2023, for edible aerial mycelium, methods of preparation, and food products containing them. The application includes hybrid food products with aerial mycelium and meat.

Patent Application: Complex for Cartilage Differentiation

The USPTO has published a new patent application (US20260083780A1) detailing a complex for promoting cartilage differentiation. The application describes a method for fabricating cartilage and a pharmaceutical composition for treating arthropathy, filed on June 2, 2025.

Antimicrobial use of Micrococcus porci against Staphylococcus species

The USPTO has published a patent application detailing the selective antimicrobial use of Micrococcus porci against harmful Staphylococcus species. The application describes compositions comprising Micrococcus porci for use in cosmetics, quasi-drugs, external skin preparations, or medicines.

Patent Application for Engineered Bacteriophage Transducing Particles Production

The USPTO has published a new patent application (US20260083787A1) from TROBIX BIO LTD. for systems and methods for producing engineered bacteriophage transducing particles. The application details novel approaches for manipulating bacterial populations using these particles and associated regulatory elements.

Patent Application for Treating DNAse1 Deficiency Diseases

The USPTO has published a new patent application (US20260083828A1) detailing compositions and methods for treating diseases associated with DNAse1 and/or DNAse1L3 deficiency. The application was filed on September 11, 2025, by inventors Demetrios Braddock, Paul Stabach, and Ethan Lester.

Patent Application: Alpha-Glucosidase Compositions for Pompe Disease Treatment

The USPTO has published a new patent application (US20260083829A1) from Amicus Therapeutics, Inc. The application details compositions comprising high concentrations of acid alpha-glucosidase and active site-specific chaperones for treating Pompe disease. It also covers methods for increasing enzyme stability.

mRNA Vaccine and Immune Modulator Combination Patent Application

The USPTO has published a patent application (US20260083837A1) for a combination comprising mRNA molecules for vaccines or therapeutic proteins, along with immune-modulating mRNA. The application details combinations for improved or reduced immunogenicity to increase efficacy, and relates to host cells, pharmaceutical compositions, vaccines, and kits for medical use.

Patent Application: Conditioned Media, Cultured Cells Production

The USPTO has published a new patent application, US20260083818A1, detailing a system and method for the production, formulation, and use of conditioned media and cultured cells. The application was filed on May 7, 2025, and describes techniques for culturing various cell types, including animal and plant cells, together.

CRISPR/Cas13a Kit for Rapid ALV-J Detection

The USPTO has published a patent application for a CRISPR/Cas13a kit designed for the rapid detection of avian leukosis virus subgroup J (ALV-J). This application details a method combining CRISPR/Cas13a with recombinase aided amplification for improved sensitivity and specificity in detecting ALV-J.

Use of G007-LK for Osteogenic Differentiation and Bone Regeneration

The USPTO has published patent application US20260085289A1, detailing the use of a compound known as G007-LK. The application, filed by the Hospital of Stomatology, Guangzhou Medical University, describes G007-LK's potential to promote osteogenic differentiation of dental stem cells and aid in bone tissue regeneration.

GalNAc Monomer for Liver-Targeted Nucleic Acid Drug Delivery

The USPTO has published a patent application detailing a GalNAc monomer for liver-targeted delivery of small nucleic acid drugs. The application, filed by inventors Zeao Huang et al., describes a compound that enhances drug efficacy through efficient liver targeting.

Patent Application: Iron Metabolism Targets for Obesity Treatment

The USPTO has published a new patent application (US20260085321A1) detailing methods for treating obesity by inhibiting specific iron metabolism genes. The application, filed on September 24, 2025, by inventor Richard Possemato, proposes inducing weight loss through increased lipid catabolism.

Engineered Ketoreductases for Chiral Alcohol Preparation

The USPTO has published a patent application (US20260085334A1) for engineered ketoreductase polypeptides developed by Enzymaster (Ningbo) Bio-Engineering Co., Ltd. The patent describes enzymes capable of preparing chiral alcohols with high catalytic activity, stereoselectivity, thermal stability, and solvent tolerance.

Method for Producing Oil Composition via Biomass Fermentation

The USPTO has published a patent application detailing a method for producing an oil composition through the fermentation of biomass using specific yeast strains. The application outlines a preparation stage, a fermentation stage with controlled temperature and pH, and an oil procurement stage involving mechanical cell lysis.

Patent Application for Metabolism Disease Therapeutic Agents

The USPTO has published a new patent application (US20260085322A1) for therapeutic agents targeting metabolism-associated diseases, such as MAFLD. The application was filed on September 6, 2023, by inventors from the USPTO.

HT Hadat Cosmetics Trademark Publication

The USPTO has published the trademark application for HT Hadat Cosmetics for opposition. The application covers a broad range of services including import-export, commercial information, advertising, business auditing, and marketing services.

B.PINK Trademark Application Published for Opposition

The USPTO has published the trademark application for 'B.PINK' for opposition. This publication pertains to a wide range of digital and telecommunication services related to health management, fitness, nutrition, and well-being.

VPX Trademark Application Published for Opposition

The USPTO has published the trademark application for 'VPX' for medical and surgical instruments, apparatus, and implants, as well as medical and healthcare clinic services. The application was published for opposition on March 26, 2026, with a filing date of April 30, 2025.

MYHEALTHPRAC trademark published for opposition

The USPTO has published the trademark application for MYHEALTHPRAC, which covers software development for mobile applications and advisory services relating to healthcare. The application was published for opposition on March 26, 2026, following a filing date of February 26, 2025.

EYEQ trademark application published for opposition

The USPTO has published the trademark application for 'EYEQ' for opposition. The application covers a range of medical and psychological services, as well as related software and training. The publication date is March 26, 2026, with a filing date of July 30, 2024.

Proposed Rescission of LGBTQI+ Children Placement Requirements

The Administration for Children and Families (ACF) proposes to remove the 'Designated Placement Requirements Under Titles IV-E and IV-B for LGBTQI+ Children' rule. This action follows a court decision vacating the rule, which had required specific placement availability for LGBTQI+ children in foster care. ACF is seeking public comment on this proposed rescission.

HANPO PATCH Trademark Application - Herbal Mud Packs

The USPTO has received an intent-to-use trademark application for 'HANPO PATCH' for goods including herbal mud packs, medicinal herbs, and dressings. The application was filed on March 25, 2026, with an intended use date of March 26, 2026.

SMILE+ DAILY ORAL DEFENSE Trademark Application

The USPTO has received an intent-to-use trademark application for 'SMILE+ DAILY ORAL DEFENSE' filed on March 25, 2026. The application covers dietary and nutritional supplements. This filing indicates a future intention to use the mark in commerce.

VERO Intent to Use Trademark Application Filed

The USPTO has received an intent-to-use trademark application for the mark 'VERO'. The application, filed on March 25, 2026, covers dietary and nutritional supplements, including satiety beverages and powdered drink mixes.

Fertility Centers of New England Registered Trademark

The USPTO has registered a trademark (TM78517534) for Fertility Centers of New England, covering medical services, laboratory, and research services. The trademark was registered on March 26, 2026, with a filing date of November 16, 2004.

AHEALTHYME Trademark Registration

The USPTO has registered the trademark AHEALTHYME (TM78491961) for services providing health information via an internet website. The registration was finalized on March 26, 2026, based on a filing date of September 30, 2004.

AIX Trademark Application for Dental Services

The USPTO has received an intent-to-use trademark application for the mark AIX, filed by an unspecified applicant. The application covers a range of dental services and products, including denture fitting, oral surgery, dental implants, and custom prosthetics. The filing date for this application was March 25, 2026.

GCVS veterinary services trademark registered

The USPTO has registered the trademark GCVS GULF COAST VETERINARY SPECIALISTS for veterinary services, including dermatology, allergy, internal medicine, neurology, oncology, diagnostic imaging, surgery, and orthopedics. The registration is effective March 26, 2026.

AMA LA Trademark Registration - Educational and Health Services

The USPTO has registered trademark TM77473347 for AMA LA, covering educational services in cosmetics, health care, and essential oils, as well as consultation and health care services. The trademark was registered on March 26, 2026, with a filing date of May 13, 2008.

AMALA Trademark Registration (TM77347849) - Medical Services

The USPTO has registered trademark TM77347849 for the mark AMALA, covering a range of medical, health care, and cosmetic services. The registration was finalized on March 26, 2026, following a filing date in December 2007.

Rabid Skunks Confirmed in Pickens County; One Person and One Horse Exposed

The South Carolina Department of Public Health confirmed two skunks tested positive for rabies in Pickens County, leading to exposure for one person and one horse. The notice reminds residents of rabies vaccination requirements for pets and livestock.

MDHHS Seeks Applications for Victim Advocacy and Response Services Grant

The Michigan Department of Health and Human Services (MDHHS) is seeking applications for victim advocacy and system response services through the STOP Violence Against Women Formula Grants program. Approximately $1.763 million is available, with grant applications due May 1, 2026.

CMS Seeks Public Comment on Information Collection Activities

The Centers for Medicare & Medicaid Services (CMS) is seeking public comment on its intention to collect information, specifically regarding the State-based Exchange Annual Reporting Tool (SMART). This notice provides an opportunity for comment on the necessity, utility, and burden of the proposed information collection.

CMS Seeks Public Comment on Information Collection Activities

The Centers for Medicare & Medicaid Services (CMS) is seeking public comment on its intention to collect information from the public, as required by the Paperwork Reduction Act. This notice provides an opportunity for comment on the necessity, utility, and burden of proposed information collections, including those related to Qualified Health Plan (QHP) certification.

FDA Approves Kresladi, First Gene Therapy for Severe LAD-I

The FDA has approved Kresladi (marnetegragene autotemcel), the first gene therapy for severe Leukocyte Adhesion Deficiency Type I (LAD-I) in pediatric patients. This accelerated approval offers a new treatment option for a rare inherited immune deficiency, targeting the underlying genetic cause of the disease.

Patent Application for Fiber-Based Prebiotic Dietary Supplements

The USPTO has published a patent application (US20260083772A1) for powder compositions comprising fiber intended for use as a prebiotic dietary supplement. The application details therapeutic ingredients and manufacturing processes aimed at improving gut microbiome and overall gut health.

Cancer Treatment Methods Using Tumor Treating Fields, Chemotherapy, and Anti-Fibrotic Agents

The USPTO has published a patent application detailing methods for treating cancer. The application describes compositions and systems involving the concurrent application of tumor treating fields, chemotherapeutic agents, and anti-fibrotic agents to reduce cancer cell viability and tumor growth.

Patent Application: Sigmari Ligand for Pancreatic Cancer Treatment

The USPTO has published a patent application (US20260083725A1) for a Sigmari Ligand for the treatment of pancreatic cancer. The application details a method involving a Sig-1R ligand to inhibit tumor growth and metastasis, filed on August 9, 2023.

Biopolymers for Ophthalmic Use Patent Application

The USPTO has published a patent application (US20260083771A1) for biopolymers intended for ophthalmic use, filed by ExoPolymer, Inc. The application details biopolymers comprising repeating polysaccharide units, their preparations, ophthalmic compositions, and methods of use.

Patent Application: Acetic Acid and Hypochlorous Acid Compositions for Skin Trauma Treatment

The USPTO has published a new patent application (US20260083774A1) detailing compositions containing hypochlorous acid and acetic acid for treating skin trauma and biofilms. The application was filed on September 22, 2025, and published on March 26, 2026.

Pegylated Menaquinol Compositions and Treatment Methods Patent Application

The USPTO has published a patent application (US20260083773A1) for pegylated menaquinol compositions and methods of treatment. The application, filed on December 5, 2025, discloses isolated, stable, and biologically active pegylated menaquinol derivatives for treating various diseases.

Patent Application: Cytotoxic Lymphocyte Activation and Expansion

The USPTO has published patent application US20260083776A1 concerning methods for activating and expanding cytotoxic lymphocytes with decreased exhaustion potential. The application details micropatterned surfaces and biofunctionalization techniques for cell expansion, potentially impacting future therapeutic development in oncology.

Metal nanoparticle agglomerates for infection control and water purification

The USPTO has published a patent application detailing the use of metal nanoparticle agglomerates for infection control and water purification. The application describes antiseptic substrates and fluid formulations incorporating these agglomerates for topical or oral use, aiming to provide infection control against infective agents.

USPTO Patent Application for Compounds Targeting Pax3/Foxo1 Fusion Protein

The USPTO has published patent application US20260083724A1, filed by Georgetown University, for novel compounds designed to target the PAX3::FOXO1 fusion protein. These compounds aim to reduce protein levels and treat fusion-positive rhabdomyosarcoma.

Guidance on Post-Flood Cleanup and Health Safety

The Hawaiʻi Department of Health (DOH) has issued guidance for residents impacted by recent flooding. The guidance provides recommendations for safe cleanup procedures, mold prevention, and floodwater safety to protect public health during recovery efforts.