Patent Application for Chromophores with New Ring-Locked Donors

The USPTO has published a new patent application (US20260085189A1) filed by Lightwave Logic, Inc. The application describes novel nonlinear optical (NLO) chromophores with ring-locked donors designed to increase r33 and stability. The filing date was September 23, 2025.

Patent Application for Psilocin Derivatives for Treating Disorders

The USPTO has published a patent application (US20260085040A1) for psilocin derivatives, including carbohydrate and amino acid conjugates. These compounds are intended for the treatment of various neuropsychiatric, neurodegenerative, neuroinflammatory, and pain disorders.

Psilocin Crystalline Forms Patent Application

The USPTO has published a patent application (US20260085039A1) detailing crystalline forms of psilocin, including salts and cocrystals. The application, filed by Jim Gilligan and Peter Guzzo, describes these forms as having improved physical properties like aqueous solubility and stability, suitable for various administration routes.

Novel Nootropic Prodrugs of Phenethylamine

The USPTO has published a patent application (US20260085036A1) for novel nootropic prodrugs of phenethylamine, assigned to MiHKAL GmbH. The application describes compounds designed to improve phenethylamine uptake and reduce side effects, potentially for treating conditions like depression and PTSD.

Patent Application for GYS1 Inhibitors

The USPTO has published a patent application (US20260085034A1) for N-(BENZHYDRYL)CYCLOALKYLCARBOXAMIDE derivatives as inhibitors of Glycogen Synthase 1 (GYS1). The application details compounds and methods for preparing them, as well as methods for inhibiting GYS1 and treating GYS1-mediated diseases.

Patent Application for Artemisinic Acid Derivative Preparation

The USPTO has published a patent application (US20260085030A1) for an artemisinic acid derivative and its preparation method. The application, filed by Yunnan Botanee Bio-Technology Group Co., Ltd., aims to improve the water solubility of artemisinic acid and dihydroartemisinic acid while retaining their whitening, anti-inflammatory, and anti-tumor properties.

Chromophores with New Bridges that Increase Refractive Index

The USPTO has published a patent application (US20260085236A1) for Lightwave Logic, Inc., detailing new nonlinear optical (NLO) chromophores designed to increase refractive index. These chromophores offer improved electro-optic effects, modulation speed, photostability, and thermal stability, making them suitable for low-power, small-footprint electro-optic devices.

New Polymers and Methods Patent Application

The USPTO has published a new patent application, US20260085336A1, detailing processes for forming pyridinedicarboxylic acid derivatives and copolymers. The application, filed on September 25, 2025, outlines biocatalytic methods and potential uses for these new materials.

Patent Application for Novel Compound Treating Neurodegeneration and Cardiovascular Diseases

The USPTO has published a patent application (US20260085083A1) for a novel compound and pharmaceutical composition developed by SHANDONG RUZHI BIOMEDICINE TECHNOLOGY CO., LTD. The compound is intended for preventing or treating neurodegenerative diseases and cardiovascular/cerebrovascular diseases.

KDM1A Inhibitors for Disease Treatment Patent Application

The USPTO has published a new patent application (US20260085082A1) from Imago Biosciences, Inc. The application discloses new compounds and compositions for pharmaceutical use, specifically for inhibiting KDM1A and increasing gamma globin gene expression to treat diseases like acute myelogenous leukemia.