Patent Application for Artemisinic Acid Derivative Preparation

ChangeBridge: Patent Apps - Organic Chemistry (C07D)

Published October 28th, 2025

Detected March 26th, 2026

Summary

The USPTO has published a patent application (US20260085030A1) for an artemisinic acid derivative and its preparation method. The application, filed by Yunnan Botanee Bio-Technology Group Co., Ltd., aims to improve the water solubility of artemisinic acid and dihydroartemisinic acid while retaining their whitening, anti-inflammatory, and anti-tumor properties.

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What changed

This document is a published patent application from the USPTO detailing a new artemisinic acid derivative. The invention focuses on creating water-soluble forms of artemisinic acid or dihydroartemisinic acid through reactions with organic compounds, peptides, or basic metal compounds. The application highlights the potential benefits of these derivatives, including improved solubility and combined biological activities such as whitening, anti-inflammatory, and anti-tumor effects, suggesting significant research and development prospects.

As this is a patent application, it does not impose immediate regulatory obligations on companies. However, it signals potential future developments in the pharmaceutical and cosmetic industries. Companies involved in the research, development, or manufacturing of artemisinic acid-based products, particularly those seeking improved formulations for topical or systemic applications, should monitor the progress of this patent application and related intellectual property.

Source document (simplified)

← USPTO Patent Applications

ARTEMISINIC ACID DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

Application US20260085030A1 Kind: A1 Mar 26, 2026

Assignee

Yunnan Botanee Bio-Technology Group Co., Ltd.

Inventors

Yichun WANG, Feifei WANG, Liping QU, Yanzhen SHEN, Zuding WANG, Qiongfen WU, Lijuan YAN, Zhaoxiang YANG, Xiao MA, Zhenyu GUO

Abstract

An artemisinic acid derivative includes: a water-soluble organic salt formed by a reaction of artemisinic acid or dihydroartemisinic acid with a small-molecule basic organic compound, or a water-soluble complex formed by a reaction of artemisinic acid or dihydroartemisinic acid with a small molecule peptide, or a water-soluble salt formed by a reaction of artemisinic acid or dihydroartemisinic acid with a basic metal compound. The artemisinic acid derivative provided by the present application solves the problem of difficulty in dissolving the artemisinic acid and the dihydroartemisinic acid in water, and combines whitening, anti-inflammatory, and anti-tumor biological activities, thus having a good research and development prospect.

CPC Classifications

C07C 57/26 A61K 8/0212 A61K 8/022 A61K 8/06 A61K 8/37 A61K 8/44 A61K 8/4926 A61K 8/64 A61K 9/107 A61K 9/19 A61K 31/19 A61K 31/198 A61K 31/455 A61K 31/4965 A61K 38/063 A61Q 1/00 C07C 51/41 C07C 51/418 C07C 51/47 C07C 229/26 C07C 279/14 C07D 213/82 C07D 241/12 C07F 1/00 C07F 1/04 C07C 2602/28