Patent: ROS-detonable Nanoclusters for Anti-Restenotic Therapy

The USPTO has granted a patent (US12582613B2) for biomimetic, reactive oxygen species-detonable nanoclusters designed for anti-restenotic therapy. The technology, assigned to the University of Virginia Patent Foundation, involves nanoclusters with self-assembled cores and biomimetic membrane coatings that can deliver anti-restenotic drugs.

Moderna Cancer Vaccines Patent Grant

The USPTO has granted patent US12582609B2 to ModernaTX, Inc. for cancer ribonucleic acid (RNA) vaccines. The patent covers cancer RNA vaccines, methods of use, and compositions. This grant is a routine notification of intellectual property protection.

USPTO Patent Grant: B-RAF Kinase Inhibitor Solid Dispersion

The USPTO has granted a patent to BeiGene, Ltd. for a stable solid dispersion of a B-RAF kinase dimer inhibitor, Compound 1. The patent covers the composition, methods of preparation, and uses of this solid dispersion, as well as a crystalline form of Compound 1.

USPTO Patent Grant: Topical Anti-inflammatory Composition with Zileuton

The USPTO has granted a patent (US12582598B2) to QURIENT CO., LTD. for a topical anti-inflammatory pharmaceutical composition comprising Zileuton. The patent covers the composition, its uses, and methods of preparation.

USPTO Grants Patent for ACE Inhibitor and Blood Pressure-Lowering Agent

The USPTO has granted a patent (US12582146B2) to MARUZEN PHARMACEUTICALS CO., LTD. for an angiotensin-converting enzyme inhibitor and blood pressure-lowering agent containing a specific compound. The patent also covers beverages and food products incorporating this compound.

USPTO Patent Granted for Dissociative Disorder Treatment Methods

The USPTO has granted a patent (US12582616B2) to The Board of Trustees of the Leland Stanford Junior University for methods of treating dissociative disorders. The patent covers agents that modulate neural activity in the posteromedial cortex to treat these conditions.

Senate Bill Waives Notice for Posthumous Promotion of Captain Cody Khork

The U.S. Senate has passed S.4138, a bill to waive the 60-day notice requirement for the posthumous honorary promotion of Captain Cody Khork of the United States Army to the rank of major. This legislative action specifically addresses an individual case to facilitate the promotion.

v. Tripp et al - Civil Case Filing

A new civil case, v. Tripp et al, was filed in the U.S. District Court for the Northern District of California on March 23, 2026. The case is classified as a Personal Injury and Product Liability matter under Diversity jurisdiction.

Tripp v. Nevro Corporation - Product Liability Lawsuit Filed

A new product liability lawsuit, Tripp v. Nevro Corporation et al., was filed in the U.S. District Court for the Northern District of California on March 23, 2026. The case involves personal injury claims related to product liability.

Ramirez v. Nevro Corporation - Product Liability Lawsuit Filed

A new civil case, Ramirez v. Nevro Corporation, was filed on March 23, 2026, in the U.S. District Court for the Northern District of California. The case involves personal injury and product liability claims, with a request for an injunction against the US government or APA vacatur.

Keene v. Pacha Soap Co - Civil Fraud Case Filing

A new civil case, Keene v. Pacha Soap Co, was filed in the U.S. District Court for the Northern District of California on March 23, 2026. The case is based on diversity jurisdiction and alleges other fraud. The filing includes a complaint and proposed summons.

Pirc v. Upgrade, Inc. - Consumer Credit Case Filing

A new civil case, Pirc v. Upgrade, Inc., was filed in the U.S. District Court for the Northern District of California on March 23, 2026. The case is based on Federal Question jurisdiction and falls under the Nature of Suit category of Consumer Credit.

Hawken v. Nevro Corporation - Product Liability Lawsuit

A new product liability lawsuit, Hawken v. Nevro Corporation, was filed on March 23, 2026, in the U.S. District Court for the Northern District of California. The complaint alleges personal injury and product liability against Nevro Corporation and other defendants, seeking injunctive relief.

Kenney v. Chime Financial, Inc. - Consumer Credit Case Filing

A new civil case, Kenney v. Chime Financial, Inc., was filed on March 23, 2026, in the U.S. District Court for the Northern District of California. The case is based on a federal question and concerns consumer credit.

Patillero, Jr. v. RH, Inc. - Other Fraud

A new civil case, Patillero, Jr. v. RH, Inc., was filed on March 23, 2026, in the U.S. District Court for the Northern District of California. The case is based on diversity jurisdiction and involves a claim of 'Other Fraud'. RH, Inc. filed a Notice of Removal from Marin Superior Court.

GG v. Noem et al - Other Immigration Actions

A civil case titled GG v. Noem et al was filed on March 23, 2026, in the U.S. District Court for the Northern District of California. The case involves 'Other Immigration Actions' and seeks an injunction against the U.S. government or APA vacatur.

Karma Nuts Inc. v. Karma Spices and Trading Company - Trademark Infringement

Karma Nuts Inc. has filed a trademark infringement lawsuit against Karma Spices and Trading Company, Inc. The case was filed in the U.S. District Court for the Northern District of California on March 23, 2026. The filing includes a complaint, certificate of interested entities, and a report on trademark filing.

Kang et al v. Meta Platforms, Inc. et al - Civil Case Filing

A new civil case, Kang et al v. Meta Platforms, Inc. et al, was filed in the U.S. District Court for the Northern District of California. The case involves federal question jurisdiction and is categorized under 'Other Statutory Actions'. The filing date and last filing date were both March 23, 2026.

Wells v. Silva - Habeas Corpus Case Filing

A habeas corpus case titled Wells v. Silva was filed on March 23, 2026, in the U.S. District Court for the Northern District of California. The filing includes a petition, a consent to proceed before a US Magistrate Judge, and a motion for leave to proceed in forma pauperis.

Malmstein et al v. 6Sense Insights, Inc. - Civil Case Filing

A new civil case, Malmstein et al v. 6Sense Insights, Inc., was filed in the U.S. District Court for the Northern District of California on March 23, 2026. The case was removed from San Francisco Superior Court under diversity jurisdiction, with 6Sense Insights, Inc. as the defendant.

Doe v. Uber Technologies - Civil Complaint

A civil complaint was filed by Jane Doe NLG (J.A.) against Uber Technologies, Inc., Rasier, LLC, and Rasier-CA, LLC on March 23, 2026. The case, filed in the U.S. District Court for the Northern District of California, is based on diversity jurisdiction and concerns personal injury. The filing fee was $405.

USA v. Varela-Hernandez - Criminal Case Filing

The U.S. District Court for the Northern District of California has filed a new criminal case, USA v. Varela-Hernandez. The case was filed on March 23, 2026, and assigned to Judge Jon S. Tigar. No summary of the case is currently available.

Manley v. Nevro Corporation - Product Liability Lawsuit

A new product liability lawsuit, Manley v. Nevro Corporation, was filed in the U.S. District Court for the Northern District of California on March 23, 2026. The case involves personal injury claims related to product liability. The filing includes a complaint and a proposed summons.

Santiago v. General Motors LLC - Civil Case Filing

A new civil case, Santiago v. General Motors LLC, was filed in the U.S. District Court for the Northern District of California on March 23, 2026. The case was removed from the Superior Court of California, County of Monterey, by General Motors LLC. The filing includes a Notice of Removal and a Certificate of Interested Entities.

Roe v. Uber Technologies - Personal Injury Product Liability

A new civil case, Roe v. Uber Technologies, Inc., was filed on March 23, 2026, in the U.S. District Court for the Northern District of California. The case is classified as a Personal Injury Product Liability matter and is based on Diversity jurisdiction.

Roe CL 294 v. Uber Technologies, Inc. - Personal Injury Product Liability Complaint

A new civil complaint has been filed in the U.S. District Court for the Northern District of California. The case, Roe CL 294 v. Uber Technologies, Inc. et al., is a personal injury product liability suit. The complaint was filed on March 23, 2026.

Ortiz v. Unum Life Insurance Company of America - ERISA Benefits Dispute

A new civil case, Ortiz v. Unum Life Insurance Company of America, has been filed in the U.S. District Court for the Northern District of California. The case concerns a dispute over employee benefits under an ERISA plan, with a complaint filed on March 23, 2026.

Mounteer v. Nevro Corporation - Product Liability Lawsuit

A new civil lawsuit, Mounteer v. Nevro Corporation, was filed in the U.S. District Court for the Northern District of California. The case is based on diversity jurisdiction and involves a product liability claim for personal injury. The filing date was March 23, 2026.

Trip v. Nevro Corporation et al - Personal Injury Product Liability

A new civil case, Trip v. Nevro Corporation et al, was filed on March 23, 2026, in the U.S. District Court for the Northern District of California. The case is classified as a Personal Injury Product Liability matter under Diversity jurisdiction.

Appeal against conviction by Kassim Nicholas against His Majesty's Advocate

The Scottish High Court of Justiciary heard an appeal against conviction by Kassim Ashley Green Nicholas. The appeal is based on alleged new evidence not presented at trial. The court is considering whether this evidence warrants a new trial.

Cahlum Hamilton appeal against sentence High Court of Justiciary

The High Court of Justiciary in Scotland heard an appeal against a sentence imposed on Cahlum Hamilton, who was 17 at the time of the offenses. The appeal challenges the imposition of an order for lifelong restriction with a punishment part of two years for charges including assault with a machete and possession of a bladed article.

CBSA Final Dumping Decision: Oil Country Tubular Goods from Mexico, Philippines, Türkiye, South Korea, USA

The Canada Border Services Agency (CBSA) has made a final determination of dumping for oil country tubular goods originating in or exported from Mexico, the Philippines, Türkiye, South Korea, and the USA. This decision imposes provisional duties on these goods.

ASIC Extends Super Trustee Transfer Relief to 2031

ASIC has extended the intra-fund transfer relief for superannuation trustees by five years, until 1 April 2031. This extension provides clarity on application form and cooling-off period requirements, continuing relief previously set to expire in April 2026. The decision follows a consultation period where all submissions supported the proposed extension.

SEC Approves Cboe Exchange Rule Change for Market-Maker Orders

The Securities and Exchange Commission (SEC) has approved a rule change proposed by Cboe Exchange, Inc. This change permits market-maker orders to be solicited as the contra-side order in certain exchange auctions. The approval was published on March 24, 2026.

SEC Order Grants Accelerated Approval for Cboe EDGX Rule Change on Retail Price Improvement

The SEC has granted accelerated approval for a rule change proposed by Cboe EDGX Exchange, Inc. The rule change modifies EDGX Rule 11.21 to adopt a Retail Price Improvement Program and adjusts other rules to describe the behavior of orders containing non-displayed instructions. This action aims to enhance price improvement opportunities for retail investors.

MIAX PEARL LLC Rule Change Approval for Sub-Dollar Securities

The SEC has approved a rule change for MIAX PEARL LLC, allowing for 'post only' orders in sub-dollar securities. This notice details the approval of the proposed rule change filed by MIAX PEARL.

Cboe Exchange Inc. Fee Schedule Amendment - Floor Booth Fees

The SEC has published a notice regarding Cboe Exchange Inc.'s proposed rule change to amend its fee schedule. This amendment specifically addresses floor booth fees. The filing was effective immediately upon filing.

SEC - Agency Information Collection Activities; Form N-14 Extension

The SEC has published a notice requesting public comment on an extension for Form N-14, an information collection activity. This notice is part of the agency's standard review process for information collections under the Paperwork Reduction Act.

SEC Notice: FP Strategies LLC Filing

The Securities and Exchange Commission has published a notice regarding a filing by FP Strategies LLC and other entities. This notice pertains to an application filed on February 6, 2026, under the Investment Company Act.

Advisors Series Trust and Scharf Investments, LLC Notice

The Securities and Exchange Commission has issued a notice regarding Advisors Series Trust and Scharf Investments, LLC. This notice pertains to an application filed on October 3, 2025, and amended on February 27, 2026, under the Investment Company Act.

Cboe Exchange Inc. Fee Adjustments for FINRA Fees

The SEC has published a notice regarding a proposed rule change by Cboe Exchange Inc. to amend its fee schedule. This change is intended to reflect adjustments to certain FINRA fees, ensuring alignment between exchange and regulatory fees.

Transportation Council Public Meeting Announcement

The Department of Transportation has issued a notice announcing a public meeting for the Beautifying Transportation Infrastructure Council. The meeting is scheduled for March 31, 2026, and details on how to access the meeting will be provided online.

Nashoba Valley Viticultural Area Established

The Alcohol and Tobacco Tax and Trade Bureau (TTB) has established the Nashoba Valley Viticultural Area. This rule defines a specific geographic region for the cultivation of grapes and the production of wine, impacting agricultural producers and wineries within the designated area.

Establishment of the Nine Lakes of East Tennessee Viticultural Area

The Alcohol and Tobacco Tax and Trade Bureau (TTB) has established the Nine Lakes of East Tennessee Viticultural Area. This final rule defines a new geographical designation for wine production, impacting labeling and origin claims for wines from this region.

Proposed Champlain Valley of Vermont Viticultural Area

The Alcohol and Tobacco Tax and Trade Bureau (TTB) has proposed establishing a new viticultural area, the Champlain Valley of Vermont. This proposal defines a specific geographic region for wine production, which may impact labeling and marketing for wineries in the area.

Polyethylene Terephthalate Film, Sheet, and Strip Determinations from China, India, Taiwan, UAE

The International Trade Commission has published a notice regarding determinations for Polyethylene Terephthalate (PET) Film, Sheet, and Strip from China, India, Taiwan, and the United Arab Emirates. This notice pertains to ongoing investigations and reviews.

Oil Country Tubular Goods Reviews Scheduled

The International Trade Commission has scheduled full five-year reviews for oil country tubular goods from India, South Korea, Turkey, Ukraine, and Vietnam. These reviews will determine if existing antidumping and countervailing duty orders should be continued.

Estate of Troy Michael Shafer v. Daryl T Parker Md - Medical Malpractice Appeal

The Michigan Court of Appeals vacated and remanded a trial court's decision, finding that the trial court abused its discretion by denying a motion to amend a complaint and affidavit of merit in a medical malpractice case. The case involves the estate of a deceased inmate suing a healthcare provider and its employee.

Platsis v. Calhoun County - Creek Maintenance Denied

The Michigan Court of Appeals affirmed a lower court's decision denying a motion to compel creek maintenance and dismissing the case. The plaintiff had sought to force the Calhoun County Water Resources Commissioner to clean Helmer Creek, a request that has been unsuccessful in previous legal efforts.

People of Michigan v. Johnny Lee Tucker - Meth Conviction Affirmation

The Michigan Court of Appeals affirmed the meth conviction and sentence of Johnny Lee Tucker. The court found no errors in the lower court's proceedings, upholding the jury's verdict and the sentence imposed.