2,6-dioxo-3,6-dihydropyrimidine compound, bactericide, nematicide, and antifungal agent

USPTO granted patent US12593845B2 to Nippon Soda Co., Ltd. on April 7, 2026, covering a 2,6-dioxo-3,6-dihydropyrimidine compound for use as an agricultural and horticultural bactericide, nematicide, and medical/veterinary antifungal agent. The patent contains 4 claims and names 9 inventors including Takaaki Teranishi and Hajime Shimomura.

STAT3 inhibitor prodrug patent compositions

USPTO granted patent US12594265B2 to Ohio State Innovation Foundation for prodrug compositions inhibiting STAT3 (including STAT3). The patent covers pharmaceutical compositions for treating inflammatory disorders (including multiple sclerosis) and cancers of uncontrolled cellular proliferation. Inventors: Yuhong Yang, Chenglong Li, Michael Racke. Application No. 17821286, 19 claims.

Bioactive benzocycloheptene analogues as PI3K/MK2 inhibitors

USPTO granted Patent US12595234B2 to the Council of Scientific & Industrial Research for bioactive benzocycloheptene analogues that inhibit PI3K and MK2. The patent covers compounds for treating type 2 diabetes, inflammatory conditions, epilepsy, cancer, and CNS disorders. The patent contains 10 claims.

MDM2 Inhibitor Patent Granted to Bahcesehir University

The USPTO granted Bahcesehir University Patent No. US12595232B2 for a novel Mouse Double Minute 2 (MDM2) inhibitor compound. The patent covers formula (I) compounds or pharmaceutically acceptable derivatives for inhibiting MDM2 activity. Application No. 17904403 was filed February 16, 2021, and the patent contains 2 claims.

EIA Requests Extension of Nuclear Fuel Data Survey Form GC-859

The Energy Information Administration (EIA) requests a three-year extension with changes to Form GC-859 Nuclear Fuel Data Survey (OMB Control No. 1901-0287). The amendment reinstates Section C.2, Projected Assembly Discharges, and requires reporting of at least three cycles to address the five-year gap between survey collections. Comments are due May 6, 2026.

Arms Export Control Act Violation Disclosure Information Collection

The State Department published a 60-day notice requesting OMB approval for a new information collection on disclosure of violations of the Arms Export Control Act. The Directorate of Defense Trade Controls is seeking public comments on the proposed requirements for reporting violations. The comment period closes June 8, 2026.

External Research Records, State-10 - System of Records Rescinded

The Department of State issued a notice rescinding the Privacy Act system of records for External Research Records, State-10. The system, which managed information related to consultant programs and external research activities, was decommissioned on May 31, 1999 following the merger of the U.S. Arms Control and Disarmament Agency (ACDA) into the Department of State. All remaining records were transferred to the National Archives and Records Administration (NARA) per the applicable record schedule.

Report to Congress on FY13 NDAA Implementation

The Department of State published a Report to Congress pursuant to the National Defense Authorization Act for Fiscal Year 2013 (FY13 NDAA). The report documents State Department compliance with NDAA-mandated requirements and was approved by the Deputy Secretary of State on March 25, 2026. This is a one-page notice (Public Notice: 12990) providing statutory reporting to Congress.

Economic Injury Disaster Declaration for Hawaii Downtown Hilo Fire

The Small Business Administration issued Disaster Declaration #21475 (Hawaii Disaster #HI-20012) for the Downtown Hilo Fire area in Hawaii, making economic injury disaster loans available to eligible small businesses and nonprofits. The declaration covers the incident period from February 2, 2026, through the filing date. Applications for these loans must be submitted by December 3, 2026.

Actuarial Advisory Committee Public Meeting Notice

The Railroad Retirement Board published a notice announcing a public meeting of the Actuarial Advisory Committee with respect to the Railroad Retirement Account, scheduled for April 8, 2026. The meeting will address actuarial matters related to the Railroad Retirement Account. This is a routine advisory committee meeting announcement affecting railroad industry stakeholders.