STAT3 inhibitor prodrug patent compositions
Summary
USPTO granted patent US12594265B2 to Ohio State Innovation Foundation for prodrug compositions inhibiting STAT3 (including STAT3). The patent covers pharmaceutical compositions for treating inflammatory disorders (including multiple sclerosis) and cancers of uncontrolled cellular proliferation. Inventors: Yuhong Yang, Chenglong Li, Michael Racke. Application No. 17821286, 19 claims.
What changed
USPTO issued patent grant US12594265B2 to Ohio State Innovation Foundation for methods and compositions related to STAT inhibitor prodrugs, specifically targeting STAT3. The patent protects pharmaceutical compositions comprising prodrug inhibitors of STAT and their use in treating inflammatory disorders and cancers. Filing date was August 22, 2022 (Application No. 17821286), with 19 claims granted.
This patent grant creates intellectual property rights but imposes no regulatory compliance obligations on pharmaceutical companies or other entities. Organizations developing STAT3 inhibitors or related cancer/inflammatory disease therapeutics should consider potential patent infringement implications and may need to obtain licenses from the assignee for commercialization activities. No compliance deadlines or penalties are associated with this notice.
Archived snapshot
Apr 7, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Methods and compositions for inhibition of STAT3
Grant US12594265B2 Kind: B2 Apr 07, 2026
Assignee
Ohio State Innovation Foundation
Inventors
Yuhong Yang, Chenglong Li, Michael Racke
Abstract
In one aspect, the disclosure relates to prodrug compositions of a STAT inhibitor compound. In some aspects, the STAT is STAT3. Disclosed are pharmaceutical compositions comprising the prodrug inhibitors of STAT. In various aspects, the prodrug inhibitors of STAT can be used in methods of treating an inflammatory disorder, including multiple sclerosis, or a disorder of uncontrolled cellular proliferation, such as a cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
CPC Classifications
A61K 31/18 C07D 275/06
Filing Date
2022-08-22
Application No.
17821286
Claims
19
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