USPTO Patent Granted: Synthetic Lixiviant Biology for Metal Recovery

The USPTO has granted a patent (US12584191B2) to the National University of Singapore for methods of using synthetic lixiviant biology for the recovery of precious and toxic metals from anthropogenic sources, including electronic waste. The patent covers engineered biological systems for metal recovery and cyanide remediation.

USPTO Grants Psoriasis Treatment Patent to Regeneron Pharmaceuticals

The USPTO has granted a new patent (US12584174B2) to Regeneron Pharmaceuticals for a method of treating psoriasis using IFIH1 inhibitors. The patent, filed on June 9, 2022, covers specific treatment methods and identification of at-risk subjects.

USPTO Patent US12584163B2 for Genomic Alterations Evaluation

The USPTO has granted patent US12584163B2 to Foundation Medicine, Inc. for compositions and methods of evaluating genomic alterations in a sample. The patent, filed on June 11, 2019, was officially granted on March 24, 2026.

Method for Capturing RNA In Situ Structures and Interactions

The USPTO has granted a patent (US12584160B2) for a method of capturing RNA in situ higher-order structures and interactions. The method involves specific labeling and purification steps to improve the efficiency and reduce the cost of RNA interaction analysis.

USPTO Patent Grant: Method for Enhancing Anti-Tumor Response in Melanoma

The USPTO has granted a patent (US12584919B2) for a method to enhance anti-tumor T cell responses in melanoma patients with defective STING signaling. The method involves administering a demethylating agent to demethylate STING proteins in tumor cells, potentially in combination with STING agonists or tumor-infiltrating lymphocytes.

USPTO Patent US12584907B1: Hydrogel for Organoid Patterning

The USPTO has granted patent US12584907B1 for a viscoelastic hydrogel designed for organoid patterning and vascularization. The patent, assigned to The Florida State University Research Foundation, Inc., details a cell scaffold using methacrylated hyaluronic acid and dopamine-modified hyaluronic acid for culturing spinal cord models and blood-spinal cord barrier models.

USPTO Patent Grant: Coating agent for stem cell differentiation

The USPTO has granted patent US12584906B2 for a coating agent designed to induce pluripotent stem cells to differentiate into brain microvascular endothelium-like cells. The patent, assigned to Nagoya City University, aims to facilitate a stable supply of these specialized cells for research and potential therapeutic applications.

USPTO Patent Grant for Chimeric Antigen and T Cell Receptors

The USPTO has granted patent US12583923B2 to Kite Pharma, Inc. for chimeric antigen and T cell receptors and methods of use. The patent covers novel CAR or TCR constructs designed for potential cancer treatment applications.

USPTO Patent Grant: Lewy Body Disorder Treatment

The USPTO has granted a patent (US12583894B2) to the University of Florida Research Foundation, Inc. for methods of treating Lewy body disorders. The patent covers administering a T cell specific for an alpha-synuclein mutant to reduce Lewy bodies in the central nervous system.

USPTO Patent Grant: Liquid Extraction from Solid Phase

The USPTO has granted patent US12582924B2 for a method of obtaining liquid from a solid phase, particularly useful for nucleic acid extractions. The patent, assigned to Cambridge Enterprise Limited, describes an improved liquid extraction technique that increases recovery compared to existing methods.