Orthotic and Prosthetic Device and Manufacturing System and Method

USPTO granted patent US12594173B2 to Hanger, Inc. for an orthotic and prosthetic device including a socket, fasteners, and pylon system. The patent covers the mechanical coupling design between socket components and pylon through threaded fasteners extending through aligned through-holes and blind-holes. This patent affects medical device manufacturers developing prosthetic limbs.

PathAI Patent - AI Pathology Tissue Prediction Statistical Model

The USPTO granted Patent US12597523B1 to PathAI, Inc. on April 7, 2026. The patent covers systems and methods for training a statistical model to predict tissue characteristics for pathology images using annotated image patches and machine learning techniques. The patent contains 17 claims and was filed on January 16, 2024.

Cancer evolution detection and diagnostic methods

The USPTO granted patent US12597524B2 to Guardant Health, Inc. covering methods for determining probability that a cancer patient's initial mutational state will develop a subsequent state after therapeutic interventions. The patent enables healthcare providers to select treatment courses that maximize probability of desired patient outcomes.

US12597516B2 physiotherapy device control, wireless remote

US12597516B2 physiotherapy device control, wireless remote

System and method for automated diagnosis

USPTO granted patent US12597520B2 to Regents of the University of Michigan for an automated diagnosis method. The patent covers a system receiving user data inputs, converting them to stored data, determining severity indexes, predicting medical conditions, and identifying presence/absence of conditions for output. The patent contains 20 claims and is classified under G16H (Health Informatics).

Pressure Ulcer Management System and Computing Device

USPTO granted patent US12597522B2 to Ajou University Industry-Academic Cooperation Foundation covering a method and system for managing pressure ulcers using a computing device with risk evaluation and prevention management modules. The patent includes 17 claims and covers technology for assessing patient pressure ulcer risk levels and scheduling prevention activities in hospital settings.

Predictive health recommendation system using large data models

The USPTO granted Patent US12597526B2 to Included Health Inc. covering systems and methods for generating predictive data models to provide personalized health action recommendations. The patent describes acquiring service requests, identifying user features, segmenting users, generating recommended actions, determining expected values, and ranking outputs. The patent contains 20 claims and falls under CPC classifications G16H 50/70, G16H 10/60, G16H 20/00, and G06N 20/00 (health informatics and machine learning).

Insecticidal proteins from plants and methods for their use - US12595488B2

USPTO granted Patent No. 12,595,488 B2 to Pioneer Hi-Bred International, Inc. covering compositions and methods for producing insecticidal proteins derived from plants. The patent claims 10 protected compositions including nucleic acid sequences, expression vectors, and transformed organisms useful for controlling Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran, and nematode pest populations.

Sterile genes and related constructs and applications thereof

USPTO granted patent US12595489B2 to SINOBIOWAY BIO-AGRICULTURE GROUP CO. LTD. covering isolated polynucleotides, polypeptides, and recombinant DNA constructs for regulating plant sterility, with 3 claims allowed under CPC classification C12N 15/829. The patent, which issues from application 17597380 filed July 5, 2019, provides intellectual property protection for sterility gene technology in plants.

Rapamycin resistant cells

Seattle Children's Hospital has been granted US Patent 12595492B2 for rapamycin resistant cell compositions and methods. The patent covers proteins expressed in host cells to confer rapamycin resistance, with applications in modulating cell signaling and selective cell expansion. The patent contains 32 claims with six named inventors including Andrew M. Scharenberg and David J. Rawdings.