Insecticidal proteins from plants and methods for their use - US12595488B2
Summary
USPTO granted Patent No. 12,595,488 B2 to Pioneer Hi-Bred International, Inc. covering compositions and methods for producing insecticidal proteins derived from plants. The patent claims 10 protected compositions including nucleic acid sequences, expression vectors, and transformed organisms useful for controlling Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran, and nematode pest populations.
What changed
USPTO issued Patent US12595488B2 to Pioneer Hi-Bred International, Inc. on April 7, 2026, covering 10 claims for insecticidal proteins from plants and methods of use. The patent protects nucleic acid sequences encoding insecticidal proteins, expression vectors containing those sequences, and transformed bacteria, plants, plant cells, plant tissues, and seeds with insecticidal activity.
For agricultural firms and biotechnology companies, this patent establishes intellectual property protection for Pioneer Hi-Bred's insect control technology in the agricultural biotechnology space. Companies developing similar transformation methods or insecticidal proteins with overlapping sequences may need to evaluate freedom-to-operate considerations or seek licensing arrangements.
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Apr 7, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Insecticidal proteins from plants and methods for their use
Grant US12595488B2 Kind: B2 Apr 07, 2026
Assignee
PIONEER HI-BRED INTERNATIONAL, INC.
Inventors
Jennifer Kara Barry, Angel Elizabeth Grace D'Oliviera, Ryan Michael Gerber, Kevin Hayes, Albert L Lu, Amy Lum, Ute Schellenberger, Eric Schepers, Jeffrey Sopa, Weiping Xie, Nasser Yalpani
Abstract
Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
CPC Classifications
C12N 15/8286 C12N 15/111 C12N 15/82 A01N 63/50 C07K 14/325 C07K 14/415 Y02A 40/146 A24D 1/042 A24D 1/045
Filing Date
2023-06-29
Application No.
18344457
Claims
10
Named provisions
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