MAGEA4 Specific T Cell Receptors Patent Application

The USPTO has published a patent application (US20260085105A1) filed by Amgen Inc. for recombinant T-cell receptors designed to selectively recognize MAGE-A4-derived peptides. The application details screening for cross-reactivity and alloreactivity.

Patent Application for Detecting Immune Cells Using Fusion Proteins

The USPTO has published a new patent application (US20260085104A1) detailing fusion proteins for detecting and isolating immune cells. The application, filed by Patrick Schlegel, describes specific fusion proteins involving a dysfunctional purinergic P2X7 receptor epitope and an antibody Fc region.

Long-acting insulin compound for treating diabetes

The USPTO has published a patent application (US20260085103A1) for a long-acting insulin compound designed for treating diabetes. The application details the compound's use in pharmaceutical compositions for conditions including type-I, type-II, and gestational diabetes.

Patent Application for Synthetic Promoters and Circuits in Cancer Cells

The USPTO has published a patent application (US20260085102A1) for nucleic acid molecules designed to specifically express sequences of interest in cancer cells. The application details synthetic promoters and circuits for use in cancer treatment.

Novel Platelet Derived Growth Factor Peptide Mimetic for Cardiac Repair

The USPTO has published a patent application (US20260085101A1) for a novel platelet-derived growth factor peptide mimetic designed for cardiac repair, particularly post-infarction. The application details specific compounds, their preparation, and methods of use.

US Patent Application for Antigen Production Methods

The USPTO has published a new patent application (US20260085100A1) from The Wistar Institute of Anatomy and Biology detailing methods for manufacturing individualized vaccines. The application focuses on nucleic acid molecules encoding neoantigens specific to tumor antigens for use in subject immunization.

Stabilized trimeric class I fusion proteins patent application

The USPTO has published a patent application (US20260085096A1) for stabilized trimeric class I fusion proteins. The application details specific mutations in the HR2 domain to enhance protein stability. This is a routine publication of a new patent application.

Patent Application for AAV Capsid Variants and Uses

The USPTO has published a new patent application (US20260085095A1) detailing adeno-associated virus (AAV) capsid variants and their uses. The application was filed on June 1, 2023, and is scheduled for publication on March 26, 2026. This represents a new disclosure in the field of gene therapy vectors.

Stapled Peptide and Use Thereof Patent Application

The USPTO has published a patent application (US20260085094A1) for a stapled peptide and its use, filed by inventors Zhixiang PAN, Haiying HE, Zhigan JIANG, and Shuhui CHEN. The application details a series of stapled peptides, specifically relating to polypeptides with sequences shown in formulas (I-1)-(I-5) and (II-6), and their pharmaceutically acceptable salts.

Melanocortin Receptor Ligands Patent Application

The USPTO has published a new patent application (US20260085092A1) for compounds acting as ligands for melanocortin receptors. The application details specific compounds and their potential use in treating mammals, filed by inventors Zeng Xin Dong and Jacques-Pierre Moreau.