Function selection in industrial networks

USPTO granted patent US12591222B2 to Cisco Technology, Inc. covering methods for selecting 5G user plane functions in industrial networks based on hierarchical security model layers. The patent, filed April 24, 2023, includes 20 claims related to associating 5G functions with contextual security information and directing endpoint communications accordingly.

Haematopoietic Stem Cell Treatment

The USPTO granted patent US12589115B2 to the University of Edinburgh on March 31, 2026. The patent covers modified haematopoietic stem cells (HSCs), methods for preparing them, and their therapeutic applications including treatment of haematological disorders. A particular focus is on methods for treating conditions characterized by elevated YTHDF2 expression using YTHDF2 inhibitors. Seven claims were issued.

GABA Agonists and Antagonists for Hematopoietic Stem Cell and Megakaryocyte Progenitor Differentiation

The USPTO granted Patent US12589114B2 to Stanford University covering methods for using GABA agonists and antagonists to affect differentiation of hematopoietic stem cells and megakaryocyte progenitors. The patent claims 7 compositions and methods targeting GABRR1 expression to either inhibit or promote megakaryocyte generation and platelet production. This patent issuance provides Stanford exclusive rights to these therapeutic approaches.

Valve Material with Combined Anti-Clotting and Anti-Calcification Properties

The USPTO granted Patent US12589187B2 to Jilin Venus Haoyue Medical Limited for a valve material with synergistic anti-coagulation and anti-calcification functions. The patent describes a preparation method involving glutaraldehyde cross-linking treatment, amine compound blocking, and anticoagulant cross-linking that addresses calcification and thrombosis issues in biological valve materials.

Bladder tumor treatment, viral nanoparticle conjugates, immune therapy

The USPTO granted patent US12589165B2 to the Department of Health and Human Services covering methods for treating bladder tumors using viral nanoparticle conjugates combined with immune checkpoint inhibitors. The patent, with inventors including John Todd Schiller and Rhonda C. Kines, contains 20 claims and was filed on April 11, 2018. This represents a technology transfer of government-funded research to advance immunotherapy treatment options.

Feed additive composition containing erythritol

The USPTO granted patent US12588689B2 to Easy Bio, Inc. for a feed additive composition combining erythritol with beta-glucan (60-100 parts by weight) and/or lysophospholipid (5-10 parts by weight) per 100 parts by weight of erythritol. The erythritol is sourced from a culture medium of erythritol-producing strains. The patent contains 9 claims.

Microbial cell product patent granted to FUMI Ingredients B.V.

The USPTO granted Patent US12588687B2 to FUMI Ingredients B.V. on March 31, 2026, for a microbial cell product and its method of preparation. The patent covers mechanical cell disintegration at 15-35°C to produce extracts for food, animal feed, and cosmetic applications. The patent includes 20 claims and is valid for 20 years from the September 13, 2021 filing date.

Production of antibodies by modification of autonomous heavy chain variable domain via gene conversion

USPTO granted patent US12588664B2 to Crystal Bioscience Inc. on March 31, 2026. The patent covers transgenic animals engineered with B cells that use gene conversion for antibody diversification, involving functional immunoglobulin heavy chain genes and operably linked pseudogenes that donate sequence to enable diversification.

Cerebrolysin patent for CADASIL treatment

USPTO granted patent US12589118B2 to Ever Neuro Pharma GmbH for a method of using cerebrolysin to reduce mortality in patients with CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy). The patent includes 15 claims and was filed on August 28, 2018.

Method for producing modified pea protein

USPTO granted patent US12588686B2 to Ajinomoto Co., Inc. covering methods for producing modified pea protein with improved solubility. The method involves treating pea ground product with acid and conducting enzyme reactions using protein deamidase. The patent contains 4 claims and names three inventors.