European Patent EP4670679A3 for Mitral Valve Prosthesis

The European Patent Office has published patent EP4670679A3 for a two-stage platform for mitral valve replacement, developed by Majoro Cardiac Innovations, LLC. This patent describes a system for percutaneously deploying a mitral annular ring platform and a valved-stent prosthetic device, aiming to provide a consistent platform for various vendors.

European Patent EP4678097A3 for Neural Interface Implants

The European Patent Office has published patent EP4678097A3 for Synchron Australia Pty Limited, detailing systems and methods for controlling devices using detected changes in neural-related signals. The patent describes a neural interface implanted within a subject's brain to detect these signals and transmit input commands.

EPO Patent Bulletin - CAR for HVG Disease Treatment

The European Patent Office has published a patent bulletin regarding a CAR for use in treating HVG disease. The patent, filed by Medizinische Hochschule Hannover and Technische Universität Braunschweig, describes a nucleic acid encoding a chimeric antigen receptor with specificity for HLA-A*02 for use in suppressing immune rejection of transplants.

EPO Patent EP4671270A3: Purifying Low-pI Antibody

The European Patent Office has published patent application EP4671270A3 concerning a method for purifying antibodies with a low isoelectric point. The patent describes techniques to suppress aggregation and improve impurity removal during antibody purification processes.

EPO Patent Bulletin - Antibodies Binding to Citrullinated Histone

The European Patent Office has published a patent bulletin regarding antibodies binding to citrullinated histone 2A and/or 4, filed by Citryll B.V. The patent, EP4659807A3, relates to antibodies or binding fragments thereof directed against citrulline-containing epitopes, potentially for therapeutic use in Neutrophil Extracellular Trap (NET)-associated pathologies.

Genmab A/S Bispecific Antibodies Against CD3 and CD20 Patent

The European Patent Office published a patent application (EP4678661A3) for Genmab A/S concerning bispecific antibodies targeting CD3 and CD20. The patent abstract details their use in treating diseases requiring T cell-mediated killing of CD20-expressing cells.

Pyridazinone Compounds as Thyroid Hormone Analogs Synthesis Methods

The European Patent Office has published a patent application detailing new synthesis methods for pyridazinone compounds, which act as thyroid hormone analogs. These methods aim to improve purity, yield, and scalability for large-scale preparation, and also describe morphic forms and a treatment method for thyroid hormone resistance.

Shin-Etsu Chemical Patent for Resist Composition

The European Patent Office has published a patent application by Shin-Etsu Chemical Co., Ltd. for a novel onium salt, a chemically amplified positive resist composition, and a resist pattern forming process. The patent aims to improve resolution and reduce line edge roughness in pattern formation.

EPO Patent Application: Anti-c-Met Antibody Drug Conjugates

The European Patent Office has published a patent application (EP4656248A3) filed by AbbVie Manufacturing Management Unlimited Company for anti-c-Met antibody drug conjugates. The application details compositions and methods for using these conjugates, which are relevant to cancer treatments.

Nitrogen-Containing Heterocyclic Compound Patent Application

The European Patent Office has published patent application EP4711361A1 concerning a nitrogen-containing heterocyclic compound and its use, filed by Jiangsu Deyuan Pharmaceutical Co., Ltd. The application details compounds represented by formula (II), their stereoisomers, and pharmaceutically acceptable salts.