ChangeBridge: EPO Bulletin - Peptides (C07K)

Genmab A/S Bispecific Antibodies Against CD3 and CD20 Patent

The European Patent Office published a patent application (EP4678661A3) for Genmab A/S concerning bispecific antibodies targeting CD3 and CD20. The patent abstract details their use in treating diseases requiring T cell-mediated killing of CD20-expressing cells.

EPO Patent Bulletin - Antibodies Binding to Citrullinated Histone

The European Patent Office has published a patent bulletin regarding antibodies binding to citrullinated histone 2A and/or 4, filed by Citryll B.V. The patent, EP4659807A3, relates to antibodies or binding fragments thereof directed against citrulline-containing epitopes, potentially for therapeutic use in Neutrophil Extracellular Trap (NET)-associated pathologies.

EPO Patent EP4671270A3: Purifying Low-pI Antibody

The European Patent Office has published patent application EP4671270A3 concerning a method for purifying antibodies with a low isoelectric point. The patent describes techniques to suppress aggregation and improve impurity removal during antibody purification processes.

EPO Patent Bulletin - CAR for HVG Disease Treatment

The European Patent Office has published a patent bulletin regarding a CAR for use in treating HVG disease. The patent, filed by Medizinische Hochschule Hannover and Technische Universität Braunschweig, describes a nucleic acid encoding a chimeric antigen receptor with specificity for HLA-A*02 for use in suppressing immune rejection of transplants.