Arrowhead Pharmaceuticals Patent for AATD Treatment

The USPTO has granted Arrowhead Pharmaceuticals, Inc. a patent (US12582668B2) for methods of treating alpha-1 antitrypsin deficiency (AATD) using pharmaceutical compositions containing AAT RNAi agents. The patent filing date was June 5, 2020, and it is scheduled to be granted on March 24, 2026.

USPTO Patent Grant: Method for producing transplantable oral mucosa tissue

The USPTO has granted patent US12582750B2 to MUKOCELL GMBH for a method of producing transplantable oral mucosa tissue. This patent covers the use of specific markers to identify suitable oral mucosa for autologous grafts, particularly for urethral reconstruction or cornea implantation.

USPTO Patent Grant: AAV vectors for Schwann cell diseases

The USPTO has granted patent US12582725B2 for AAV vectors with a myelin protein zero promoter, designed for treating Schwann cell-associated diseases like Charcot-Marie-Tooth disease. The patent was assigned to The Cyprus Foundation for Muscular Dystrophy Research.

USPTO Patent Grant: Microbial Polypeptides for Glycogen Storage Diseases

The USPTO has granted patent US12582724B2 to Duke University for compositions comprising microbial polypeptides designed to treat glycogen storage diseases. The patent covers isolated nucleic acid molecules, vectors, and methods utilizing these components for therapeutic purposes.

USPTO Patent Grant US12582723B2 for FKRP Protein Polynucleotides

The USPTO has granted patent US12582723B2 to Genethon for synthetic polynucleotides encoding a human FKRP protein. These polynucleotides are designed to avoid frameshift mutations and are useful for treating pathologies linked to FKRP deficiency or defects in alpha-dystroglycan glycosylation, such as LGMD2I.

USPTO Patent US12582141B2: Phytase Activity Polypeptides

The USPTO has granted patent US12582141B2 to AB Enzymes Finland Oy for novel polypeptides with improved phytase activity. The patent covers compositions, recombinant host cells, and their use in feed applications.

USPTO Patent Granted for ST Gal(+) Bacteria in Fermented Milk

The USPTO has granted a patent (US12582133B2) to Chr. Hansen A/S for a method using ST Gal(+) bacteria to produce fermented milk products with a high stable pH. The patent covers specific bacterial strains and their application in food production.

USPTO Patent Grant: IL-15 Humanized Mouse Model

The USPTO has granted patent US12582106B2 for an IL-15 humanized mouse model and its use, assigned to GEMPHARMATECH CO., LTD. The patent details a specific genetic modification of the mouse, combining human and mouse gene segments, and outlines its preparation and application, particularly in cancer research.

Neighborhood Reinvestment Corporation Sunshine Act Meeting Notice

The Neighborhood Reinvestment Corporation has issued a notice for a Special Board of Directors meeting to be held on March 30, 2026. The meeting will include both open and closed sessions, with the closed session pertaining to the FY26 Final Budget.

USPTO PTAB Adds New IPR, CBM, and PGR Decisions

The USPTO's Patent Trial and Appeal Board (PTAB) has added new decisions for Inter Partes Review (IPR), Covered Business Method (CBM), and Post-Grant Review (PGR) proceedings. These include final written decisions for cases involving Bio-Rad Laboratories, Inc. v California Institute of Technology and Google LLC v Ericsson AB, as well as 'Settled After Institution' decisions.