Patent Application: Conditioned Media, Cultured Cells Production

The USPTO has published a new patent application, US20260083818A1, detailing a system and method for the production, formulation, and use of conditioned media and cultured cells. The application was filed on May 7, 2025, and describes techniques for culturing various cell types, including animal and plant cells, together.

CRISPR/Cas13a Kit for Rapid ALV-J Detection

The USPTO has published a patent application for a CRISPR/Cas13a kit designed for the rapid detection of avian leukosis virus subgroup J (ALV-J). This application details a method combining CRISPR/Cas13a with recombinase aided amplification for improved sensitivity and specificity in detecting ALV-J.

Use of G007-LK for Osteogenic Differentiation and Bone Regeneration

The USPTO has published patent application US20260085289A1, detailing the use of a compound known as G007-LK. The application, filed by the Hospital of Stomatology, Guangzhou Medical University, describes G007-LK's potential to promote osteogenic differentiation of dental stem cells and aid in bone tissue regeneration.

Patent Application for Feeder Cells and Cell Sheet Production

The USPTO has published a new patent application (US20260085290A1) filed by DAI NIPPON PRINTING CO., LTD. The application details a method for producing feeder cells and cell sheets, derived from pluripotent stem cells, intended for maintaining or proliferating difficult-to-culture cells. This is a standard publication of a patent application.

Patent Application: Diabetes Prevention/Treatment by Myeloid Suppressor Cell Activity

The USPTO has published a new patent application (US20260085291A1) from CREATIVE MEDICAL TECHNOLOGIES, INC. The application details methods and compositions for preventing or treating Type 1 diabetes by augmenting myeloid suppressor cell activity, potentially involving conditioned immune cells or exogenous suppressor cells.

Minimal Essential Media for Human Induced Pluripotent Stem Cells

The USPTO has published a patent application (US20260085292A1) detailing minimal essential media for culturing human induced pluripotent stem cells (iPSCs). The application was filed on September 11, 2023, by inventor Paul Wesley Burridge.

USPTO Patent Application for Body Fluid Sample Transport Solution

The USPTO has published a new patent application (US20260085293A1) detailing a solution and method for transporting or storing body fluid samples. The application, filed on March 27, 2024, by inventors Mitsumi NISHI, Noriko MIYAUCHI, and Rieko SHIMAMURA, describes a solution containing specific active ingredients for sample preservation.

Process for Producing Purified Rhabdovirus from Cell Culture

The USPTO has published a patent application detailing a process for producing a purified rhabdovirus from cell culture, specifically oncolytic rhabdoviruses like vesicular stomatitis virus. The application, filed on August 21, 2025, outlines methods for both upstream and downstream processing.

Patent Application for AAV Purification Using Anion Exchange Chromatography

The USPTO has published a patent application (US20260085295A1) detailing methods for purifying adeno-associated viruses (AAV) using anion exchange chromatography. The application, filed on September 23, 2025, by inventors Garima Thakur, Sheldon Robert Mink, and Andrew David Tustian, focuses on enhancing purification efficiency and concentration.

Bacterial Superoxide Dismutases Patent Application

The USPTO has published a patent application (US20260085297A1) filed by Novozymes A/S for bacterial superoxide dismutases. The application, filed on August 29, 2025, describes polypeptides useful in animal feed additives for improving growth, performance, and health.

Method for Efficient Biosynthesis of Rebaudioside M2 Using Glycosyltransferase

The USPTO has published a patent application detailing a method for the efficient biosynthesis of rebaudioside M2 using glycosyltransferase. The assignee, GUILIN LAYN NATURAL INGREDIENTS CORP., claims this method provides an environmentally friendly way to produce rebaudioside M2 with no by-products, potentially reducing production costs.

Patent Application for Engineered Pyrococcus Enzymes

The USPTO has published patent application US20260085299A1 for engineered Pyrococcus enzymes designed for improved nucleotide analogue incorporation in DNA sequencing. The application was filed on May 27, 2025.

Patent Application: Genome Modification Compositions and Methods

The USPTO has published a new patent application (US20260085301A1) from Confluence Genetics, LLC, detailing compositions and methods for targeting and eliminating cells with pre-determined DNA sequences using Cas12a2 protein. The application was filed on September 19, 2025.

Method to enhance CAR-T cell efficacy using NOS inhibitor

The USPTO has published a patent application (US20260083844A1) detailing a method to enhance CAR-T cell efficacy by downregulating nitric oxide synthase (NOS). This application describes a potential therapeutic approach for treating B cell malignancies that are resistant to current CAR-T cell treatments.

Patent Application: Plant Pest Control using Cas12a2 Protein

The USPTO has published a patent application (US20260085302A1) from Confluence Genetics, LLC, detailing methods and compositions for controlling plant pests using Cas12a2 protein and guide polynucleotides. The application describes targeting specific DNA or RNA sequences within plant pests for elimination.

Novel cell wall hydrolases target Cutibacterium acnes conditions

The USPTO has published a patent application (US20260085303A1) detailing novel cell wall hydrolases designed to target Cutibacterium acnes. The application describes compositions and uses for treating conditions associated with this bacterium.

Methods for adding polymers to ribonucleic acids

The USPTO has published a patent application detailing methods for adding polymers of non-canonical nucleotides to the 3' end of ribonucleic acids (RNA). The application, filed by inventors from institutions including the University of California, describes techniques that may be used for RNA analysis and identification. This publication represents a new patent application and does not impose immediate regulatory obligations.

Patent Application for Nucleic Acid Library Preparation

The USPTO has published a new patent application, US20260085306A1, detailing ligation-free methods for preparing nucleic acid libraries for high-throughput sequencing. The application was filed on January 16, 2024, and published on March 26, 2026.

Genome-wide insulator screening system disclosed

The USPTO has published a patent application detailing a genome-wide insulator screening system. The system, comprising specific MAI-seq vectors, is designed for high-sensitivity screening of genomic insulators and is applicable to any species.

Methods for Generating cDNA Library from RNA

The USPTO has published a patent application (US20260085308A1) detailing methods for the fast and efficient generation of cDNA libraries from RNA. The application, filed on September 11, 2023, by inventors Keith Brown, Steven Head, and Phillip Ordoukhanian, describes a method adaptable for automation.

Patent Application: Compositions for Treating CHD2 Haploinsufficiency

The USPTO has published a patent application (US20260085319A1) for compositions and methods to treat CHD2 haploinsufficiency. The application details a method of increasing Chromodomain Helicase DNA Binding Protein 2 (CHD2) in neuronal cells using a nucleic acid agent.

Method for Trans-Differentiating Non-Neuronal Cells into Neurons

The USPTO has published a patent application (US20260085284A1) from SHANGHAI GENEMAGIC BIOSCIENCES CO., LTD. for a method of trans-differentiating non-neuronal cells into neurons using specific regulators. The application was filed on August 30, 2023.

Patent Application for Propagator Cells and Phage Propagation Methods

The USPTO has published a new patent application (US20260085296A1) detailing propagator cells and methods for propagating phage, particularly for delivering CRISPR-Cas components via probiotic organisms. The application was filed on December 4, 2025.

EYEQ trademark application published for opposition

The USPTO has published the trademark application for 'EYEQ' for opposition. The application covers a range of medical and psychological services, as well as related software and training. The publication date is March 26, 2026, with a filing date of July 30, 2024.

B.PINK Trademark Application Published for Opposition

The USPTO has published the trademark application for 'B.PINK' for opposition. This publication pertains to a wide range of digital and telecommunication services related to health management, fitness, nutrition, and well-being.

MYHEALTHPRAC trademark published for opposition

The USPTO has published the trademark application for MYHEALTHPRAC, which covers software development for mobile applications and advisory services relating to healthcare. The application was published for opposition on March 26, 2026, following a filing date of February 26, 2025.

VPX Trademark Application Published for Opposition

The USPTO has published the trademark application for 'VPX' for medical and surgical instruments, apparatus, and implants, as well as medical and healthcare clinic services. The application was published for opposition on March 26, 2026, with a filing date of April 30, 2025.

HT Hadat Cosmetics Trademark Publication

The USPTO has published the trademark application for HT Hadat Cosmetics for opposition. The application covers a broad range of services including import-export, commercial information, advertising, business auditing, and marketing services.

Fox Chase Bank Trademark Registration for Banking Services

The USPTO has registered the trademark 'Fox Chase Bank' for banking services, as indicated by registration number TM75103519. The trademark was officially registered on March 26, 2026, following a filing date of May 13, 1996.

Autopilot Trademark Registration TM74345639

The United States Patent and Trademark Office (USPTO) has registered the trademark 'AUTOPILOT' (TM74345639) for software used to control radio frequency broadcast transmitters. The trademark was registered on March 26, 2026, with a filing date of January 5, 1993.

AMC Trademark TM74067606 Cancellation

The USPTO has cancelled trademark application TM74067606 for AMC, originally filed on June 8, 1990. The cancellation is scheduled to take effect on March 26, 2026. This cancellation pertains to a broad range of goods including testing instruments, computer hardware and software, audio/video equipment, manufacturing machinery, and lubricants.

ULTROL Registered Trademark TM73048869

The USPTO has registered the trademark TM73048869 for 'ULTROL' electrical wire and cable. The trademark was filed on April 9, 1975, and registered on March 26, 2026. This registration pertains to goods classified under Class 009.

HY-VIZ Registered Trademark for Protective Clothing

The USPTO has registered the trademark HY-VIZ (TM74643641) for protective clothing, specifically disposable safety apparel designed to be highly visible. The trademark was registered on March 26, 2026, with a filing date of February 28, 1995.

TORCHMATE Registered Trademark TM74635589 for Robot Software

The USPTO has registered the trademark TORCHMATE (TM74635589) for computer software used with industrial robots for resistance welding applications. The registration was finalized on March 26, 2026, based on a filing date of February 17, 1995.

Trademark Registration 74132257 - Temperature Sensors

The USPTO has registered trademark 74132257 for "temperature sensors indicating by color the freezing ambient temperature adjacent the area of a stretch of the driving surface for indicating whether it is frozen or not." The trademark was registered on March 26, 2026, with a filing date of January 22, 1991.

VIDAS Registered Trademark for Immunodiagnostic Assay System

The USPTO has registered the trademark VIDAS (TM74072619) for an automatic immunodiagnostic assay analysis system. The registration covers reagent strips, solid phrase receptacles, and computer systems for analyzing enzyme-linked fluorescent immunoassays for in vitro diagnostic use.

APCO Registered Trademark TM74642652 - Architectural Signs

The USPTO has registered trademark TM74642652 for APCO, covering architectural signs made primarily of plastic, including luminous and non-luminous directory, display, exterior, and interior signs. The trademark was registered on March 26, 2026, with a filing date of March 6, 1995.

GOLDMINE registered trademark for task management software

The USPTO has registered the trademark GOLDMINE (TM74599524) for task management software. The registration was finalized on March 26, 2026, based on a filing date of November 16, 1994. This registration pertains to computer programs for organization and management.

MAVERICK Trademark Registration TM74559625

The USPTO has registered the trademark MAVERICK (TM74559625) for goods and services including film and music publishing, prerecorded media, and entertainment content. The registration was finalized on March 26, 2026, based on a filing date of August 9, 1994.

Emily Reed Consent Caution

The State Bar of Arkansas has issued a consent caution to Emily Reed (Bar Number 2001020) in case number 2025-028. The document was filed on March 18, 2026, and is classified as a caution disciplinary action.

Minister Tong's Address on Maritime Law, Arbitration, and Industry Updates

Minister Edwin Tong of Singapore's Ministry of Law delivered an address at the 23rd International Congress of Maritime Arbitrators on March 22, 2026. The speech highlighted the critical importance of the maritime industry to global trade and Singapore's role within it, touching upon recent disruptions and their economic impacts.

Oklahoma Man Arrested for Soliciting Minor and Sending Explicit Images

The South Carolina Attorney General's Office announced the arrest of Brantly Leon Griffin for criminal solicitation of a minor and dissemination of obscene material to a minor. Griffin faces up to 10 years imprisonment for each felony charge.

Chester County Gang Shooting Indictment

South Carolina Attorney General Alan Wilson announced the return of a two-count indictment against Kylynn Jackson and Rajai Jones for the murder of Darius Minter in Chester County. The indictments include charges of criminal conspiracy and murder, stemming from alleged retaliatory gang violence. Bond was denied for both defendants.

AG Wilson Announces Indictments in Operation Ganjapreneur Marijuana Bust

South Carolina Attorney General Alan Wilson announced indictments in Operation Ganjapreneur, a drug trafficking investigation targeting illegal marijuana and THC products. The State Grand Jury issued indictments against alleged operators of Dab City Warehouse, LLC, and Jay's Head Shop and Wellness Center LLC, following seizures of approximately 30,000 pounds of product valued at nearly $77 million.

Man Arrested on Child Sexual Abuse Material Charges

The South Carolina Attorney General's Office announced the arrest of Richard Channing Shealy on 13 charges related to the sexual exploitation of minors. Shealy faces charges for distributing and possessing child sexual abuse material, with potential penalties of up to 10 years imprisonment per count.

AMF applies ESMA crypto-asset staff training guidelines under MiCA

The AMF in France has adopted guidelines from the European Securities and Markets Authority (ESMA) regarding the knowledge and competence of staff at crypto-asset service providers (CASPs). These guidelines, adopted by ESMA on January 28, 2026, aim to ensure CASP staff act in the best interests of clients under the MiCA regulation.

Cankun He criminal case

The U.S. District Court for the Northern District of California has filed recent documents in the criminal case against Cankun He. The filings include the U.S. opposition to He's motion for relief under the Speedy Trial Act and the Due Process Clause, with a last filing date of March 27, 2026.

Product Intervention Restricts Futures Marketing to Retail Clients

BaFin has issued a general administrative act restricting the marketing, distribution, and sale of futures to retail clients in Germany. The measure, effective January 1, 2023, prohibits investment firms from offering these products to retail clients unless specific exceptions, such as excluding additional payment obligations or confirming hedging purposes, are met.

UKRI Funding: £600,000 for STFC Science Commercialisation

UKRI is offering up to £600,000 in grant funding for UK research organisations to commercialise STFC science, specifically from particle physics, astronomy, nuclear, and solar/planetary science communities. This is an 'intention to submit' stage, with the full scheme anticipated to open in June 2026.

UKRI Diet and Health Collaborative R&D Grants Funding

UKRI has opened a call for collaborative research and development grants totaling £3.75 million to support innovations in diet and health for the UK population. The funding opportunity, managed by BBSRC and Defra, requires a 30% industry contribution and has a maximum award of £800,000 per project. Applications are open until May 27, 2026.