Energy Transmitting Device for Tinnitus Treatment via Bone Conduction

USPTO granted patent US12594007B2 to Circius Pharma AB for an energy transmitting device using bone conduction to treat tinnitus. The patent covers a two-unit system with a first unit producing treatment energy and a second unit securing the device against the patient's skin for bone conductivity transmission. The patent contains 21 claims and was filed on July 26, 2021.

Surgical Vessel Sizing System Patent Grant

USPTO granted patent US12593989B2 to Briteseed, LLC for a surgical system that determines vessel size using optical sensors. The system analyzes pulsatile and non-pulsatile light components to calculate vessel diameter. The patent names 6 inventors and contains 7 claims.

AI System for Analyzing Wearable Activity Tracker Health Data

The USPTO granted Patent US12593990B2 to Aetna Inc. on April 7, 2026, covering a system and method for using deep learning algorithms to analyze health data collected from wearable devices such as activity trackers and smartwatches. The system processes input vectors containing monitored parameter data, embedding data from health records, and optionally social determinants and demographic data to generate health condition probability classifiers. Five inventors are named: Naiqian Zhi, Benjamin Wanamaker, Rajiv Bhan, and Sumeet Kumar.

Method and device for determining a coronary microvascular resistance score

USPTO granted Patent US12593988B2 to QFR Solutions B.V. covering methods and devices for determining coronary microvascular resistance scores to assess myocardial tissue perfusion. The patent describes using blood pressure data, flow data, and throughflow geometry data to generate microvascular resistance scores via an electronic output signal for display. Medical device manufacturers developing cardiac diagnostic technologies should review this patent for potential freedom-to-operate implications.

Transmission mode-photoacoustic tomography of the human brain through an acoustic window

The USPTO granted Patent US12593986B2 to the California Institute of Technology covering photoacoustic imaging techniques for transmission mode tomography of the human brain through an acoustic window in the skull. The patent lists inventors Yang Zhang, Sri Sai Narasimha KS Dhara Venkata, and Lihong Wang, with 27 claims. This patent grant establishes enforceable intellectual property rights for diffuse light delivery and acoustic wave detection in brain imaging applications.

Quorum Sensing Compositions and Methods for Microbial Community Modulation

USPTO granted patent US12594307B2 to The Regents of the University of California for quorum sensing compositions and methods for modulating bacterial quorum sensing. The patent covers engineered bacterial strains with multiple activator polypeptide-encoding sequences and methods for tunable dynamics in microbial communities. Inventors include Jeff Hasty, Arianna Miano, and Michael Julius Liao, with applications spanning synthetic biology and therapeutic development.

Single domain antibodies for cancer therapy, Institut Curie

USPTO granted Patent US12594302B2 to Institut Curie covering fully humanized anti-FGFR4 single domain antibodies (sdAbs), functionalized drug nanocarriers, and compositions for cancer therapy. The patent includes 24 claims and covers nucleic acids, vectors, host cells, and immune cells comprising said sdAbs. The invention relates to FGFR4-targeted therapies for treating cancer.

Bispecific CAR Targeting CD19 and CD20 for Cancer Treatment

USPTO granted Patent US12594321B2 to Novartis AG for a bispecific chimeric antigen receptor (CAR) targeting CD19 and CD20 for cancer treatment. The patent covers CAR proteins, encoding nucleic acids, vectors, and methods for treating diseases associated with CD20 or CD22 expression using modified T or NK cells. The patent includes 18 claims and lists 6 inventors.

Temperature-Optimized Bacillus Strains Patent Grant

The USPTO granted patent US12593849B2 to Chr. Hansen A/S on April 7, 2026, covering new strains of Bacillus paralicheniformis with improved growth rates and plant growth promoting properties. The patent names six inventors including Patricia Dominguez Cuevas and Lars Moelbak, with 21 claims. Filing date was August 28, 2020, under application number 17638152.

Virus-like Particles Patent Granted to University of Denver

The USPTO granted Patent US12594329B2 to the University of Denver on April 7, 2026. The patent covers virus-like particles, compositions, antibody detection tests using virus-like particles, and methods of producing non-replicating virus-like particles from modified viral genomes. Schuyler B. van Engelenburg is the sole inventor of the 9-claim patent.