The USPTO issued Patent US12594329B2 (Kind B2) to the University of Denver for virus-like particle technology. The patent discloses methods for generating modified viral genomes with portions removed to produce non-replicating virus-like particles, along with related compositions and antibody detection tests. The patent was filed November 9, 2021, under application number 17522150, and contains 9 claims.

This patent grant establishes exclusionary intellectual property rights for the University of Denver in the virus-like particle technology space. Organizations engaged in virus-like particle research or development should evaluate whether their activities may fall within the scope of these claims to assess potential licensing needs or freedom-to-operate concerns.