Method and device for determining a coronary microvascular resistance score

ChangeBridge: Patent Grants - Diagnosis & Surgery (A61B)

Published April 7th, 2026

Detected April 7th, 2026

Summary

USPTO granted Patent US12593988B2 to QFR Solutions B.V. covering methods and devices for determining coronary microvascular resistance scores to assess myocardial tissue perfusion. The patent describes using blood pressure data, flow data, and throughflow geometry data to generate microvascular resistance scores via an electronic output signal for display. Medical device manufacturers developing cardiac diagnostic technologies should review this patent for potential freedom-to-operate implications.

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What changed

USPTO granted Patent US12593988B2 to QFR Solutions B.V. on April 7, 2026. The patent covers methods for determining a microvascular resistance score indicating myocardial tissue perfusion, involving acquisition of blood pressure and flow data in a cardiac vessel, generation of adjusted data corresponding to a second physiological state, and output of the resistance score via electronic signal for display.

This is a routine patent grant notice with no compliance obligations or deadlines. Medical device manufacturers and healthcare providers developing or using cardiac diagnostic methods should review this patent when assessing intellectual property positions or developing competing technologies.

Source document (simplified)

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Method and device for determining a coronary microvascular resistance score

Grant US12593988B2 Kind: B2 Apr 07, 2026

Assignee

QFR Solutions B.V.

Inventors

Javier Escaned-Barbosa, Hernán David Mejía Rentería, Johan Hendrikus Christiaan Reiber

Abstract

A method of determining a microvascular resistance score indicating perfusion of myocardial tissue in a body of a mammal is provided, comprising obtaining acquired blood pressure data and flow data of blood in a cardiac vessel while the mammal is in a first physiological state; obtaining throughflow data indicative of a geometry the cardiac vessel; generating adjusted blood pressure data and adjusted flow data corresponding to a second physiological state, based on the acquired blood pressure value and the first physiological state; generating the microvascular resistance score, based on the adjusted blood pressure data, the adjusted flow data and the throughflow data; and providing, through an electronic output signal, the microvascular resistance score for display on an electronic display module.