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Effect of Complete Suction-Induced Collapse of Renal Collecting System at End of RIRS on Early Postoperative Outcomes

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Summary

NIH ClinicalTrials.gov has registered NCT07535281, a randomized controlled trial evaluating whether actively suctioning the renal collecting system to induce collapse at the end of retrograde intrarenal surgery (RIRS) reduces postoperative pain and infection in kidney stone patients. Participants will be randomly assigned to experimental group (suction-induced collapse) or control group (standard drainage). The study aims to determine if this surgical modification improves early recovery outcomes and patient satisfaction.

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What changed

NIH ClinicalTrials.gov registered a new randomized controlled trial (NCT07535281) examining the effect of complete suction-induced collapse of the renal collecting system at the end of retrograde intrarenal surgery (RIRS) on early postoperative outcomes in patients with kidney stones. The study will compare experimental group (suction-induced collapse) versus control group (standard drainage) to evaluate differences in postoperative pain and infection rates.

For urology departments and clinical investigators conducting RIRS procedures, this trial registration signals ongoing research into surgical technique modifications that may improve patient recovery. Kidney stone patients may benefit from discussing this trial with their urologists if they are candidates for RIRS. No compliance obligations are created by this clinical trial registration.

Archived snapshot

Apr 18, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

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Effect of Complete Suction-Induced Collapse of the Renal Collecting System at the End of RIRS on Early Postoperative Outcomes

N/A NCT07535281 Kind: NA Apr 17, 2026

Abstract

The purpose of this study is to evaluate whether actively suctioning the renal collecting system to induce a "collapse" state at the end of retrograde intrarenal surgery (RIRS) can reduce postoperative pain and infection in patients with kidney stones. Participants will be randomly assigned to either the experimental group (suction-induced collapse) or the control group (standard drainage). The study aims to determine if this simple surgical modification can improve early recovery outcomes and patient satisfaction.

Conditions: Kidney Stones, Nephrolithiasis, Renal Calculi

Interventions: Complete suction-induced collapse, Standard RIRS with natural drainage

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Last updated

Classification

Agency
NIH
Published
April 17th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
NCT07535281

Who this affects

Applies to
Healthcare providers Patients
Industry sector
6211 Healthcare Providers
Activity scope
Clinical trial research Urological surgery
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Topics
Medical Devices Public Health

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