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USPTO Patent Application: Phage T4 Nanoparticle Vaccine Platform

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Summary

The USPTO has published a patent application (US20260083835A1) detailing a modular bacteriophage T4 nanoparticle vaccine platform. This platform is designed for the rapid development of dual COVID-19 and flu mucosal vaccines, administered intranasally without an adjuvant.

What changed

This document is a USPTO patent application (US20260083835A1) for a novel vaccine platform. The application describes a composition utilizing a bacteriophage T4 nanoparticle, which can display or package antigens on its surface or interior. The proposed vaccine is intended for intranasal administration and is designed to target respiratory viruses such as coronavirus and influenza, without the need for an adjuvant. The inventors listed are Venigalla B. Rao and Jingen Zhu.

As this is a patent application, it does not impose immediate regulatory requirements or compliance deadlines on regulated entities. However, it signals potential future developments in vaccine technology. Companies involved in pharmaceutical research and development, particularly in the areas of infectious disease and vaccine manufacturing, should be aware of this technological advancement. Further analysis would be required if this patent application leads to a granted patent and subsequent commercialization efforts.

Source document (simplified)

← USPTO Patent Applications

MODULAR BACTERIOPHAGE T4 NANOPARTICLE PLATFORM ENABLES RAPID DESIGN OF DUAL COVID-19-FLU MUCOSAL VACCINES

Application US20260083835A1 Kind: A1 Mar 26, 2026

Inventors

Venigalla B. Rao, Jingen Zhu

Abstract

A non-infections bacteriophage T4 nanoparticle vaccine composition includes a bacteriophage capsid and at least one antigen displayed on the surface of the capsid or packaged in its interior. The vaccine is administered intranasally and is free of an adjuvant. The antigen is selected from respiratory viruses including coronavirus and influenza.

CPC Classifications

A61K 39/145 A61K 9/0043 A61K 9/5184 A61K 9/5192 A61K 39/215 A61K 47/02 A61P 31/16 C07K 14/005 C12N 7/00 C12N 9/222 C12N 15/111 A61K 2039/5254 A61K 2039/5256 A61K 2039/543 A61K 2039/55555 A61K 2039/572 A61K 2039/575 A61K 2039/70 C07K 2319/40 C12N 2310/20 C12N 2760/16134 C12N 2770/20034 C12N 2795/10034

Filing Date

2025-09-24

Application No.

19337994

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Classification

Agency
USPTO
Instrument
Notice
Legal weight
Non-binding
Stage
Draft
Change scope
Minor
Document ID
US20260083835A1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Vaccine Development Drug Manufacturing
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
R&D
Topics
Pharmaceuticals Biotechnology

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