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MODULAR BACTERIOPHAGE T4 NANOPARTICLE PLATFORM ENABLES RAPID DESIGN OF DUAL COVID-19-FLU MUCOSAL VACCINES

Application US20260083835A1 Kind: A1 Mar 26, 2026

Inventors

Venigalla B. Rao, Jingen Zhu

Abstract

A non-infections bacteriophage T4 nanoparticle vaccine composition includes a bacteriophage capsid and at least one antigen displayed on the surface of the capsid or packaged in its interior. The vaccine is administered intranasally and is free of an adjuvant. The antigen is selected from respiratory viruses including coronavirus and influenza.

CPC Classifications

A61K 39/145 A61K 9/0043 A61K 9/5184 A61K 9/5192 A61K 39/215 A61K 47/02 A61P 31/16 C07K 14/005 C12N 7/00 C12N 9/222 C12N 15/111 A61K 2039/5254 A61K 2039/5256 A61K 2039/543 A61K 2039/55555 A61K 2039/572 A61K 2039/575 A61K 2039/70 C07K 2319/40 C12N 2310/20 C12N 2760/16134 C12N 2770/20034 C12N 2795/10034

Filing Date

2025-09-24

Application No.

19337994