United States

USPTO Patent US12583820B2: Antivirals against coronavirus

The USPTO has granted patent US12583820B2 to Kansas State University Research Foundation for broad spectrum antivirals against coronaviruses. The patent covers specific chemical compounds designed to inhibit viral replication.

Biomaterial with functionalized tyrosine, preparation method, pharmaceutical composition

The USPTO has granted a patent (US12583818B2) for a method to prepare a biomaterial with selectively functionalized tyrosine and a pharmaceutical composition containing it. This innovation aims to improve the efficacy of biomaterial drugs by ensuring selective coupling to tyrosine without affecting other amino acids or the biomaterial's inherent activity.

USPTO Patent Grant US12582652B2 for Ion Channel Modulator

The USPTO has granted patent US12582652B2 to Praxis Precision Medicines, Inc. for a novel ion channel modulator compound. The patent covers methods of treating neurological disorders and conditions associated with neuronal excitability.

USPTO Patent Grant: Chemokine CXCR4 Receptor Modulators

The USPTO has granted a patent to Emory University for chemokine CXCR4 receptor modulators and their uses. The patent covers compounds and pharmaceutical compositions that can be used for managing various conditions including viral infections, abnormal cellular proliferation, and cancer.

USPTO Patent Grant for Protein Production by Ajinomoto

The USPTO has granted patent US12584156B2 to Ajinomoto Co., Inc. for a method of producing objective proteins using animal cells. The method involves culturing animal cells with increased phosphoric acid and/or potassium concentration in the culture medium.

USPTO Patent Grant: DNA Fragment Assembly Method and Kit

The USPTO has granted patent US12584155B2 for a method and kit for assembling multiple DNA fragments at room temperature. The patent, assigned to Universitetet i Tromsø—Norges arktiske universitet, utilizes specific thermolabile DNA polymerases and exonucleases.

USPTO Patent Grant for Amberketal Production by GIVAUDAN SA

The USPTO has granted patent US12584153B2 to GIVAUDAN SA for an enzyme-mediated process for producing Amberketal and its homologues. The patent covers the method, the products, and their uses.

USPTO Patent Grant: Lipase for Metal Reduction in Distillers Corn Oil

The USPTO has granted a patent (US12584150B2) to POET Research, Inc. for a method using endogenous lipase to reduce metal content in distillers corn oil (DCO). This DCO is intended for use as a feedstock in renewable diesel production.

USPTO Patent US12584149B2: Genome Editing of Primary Cells

The USPTO has granted patent US12584149B2 to The Board of Trustees of the Leland Stanford Junior University for methods of nuclease-mediated genome editing of primary cells. The patent covers techniques for inducing stable gene modification via homologous recombination and enriching genetically modified cells using DNA nucleases and AAV vectors.

USPTO Patent Grant: Synthetic Modified Vaccinia Ankara Based Coronavirus Vaccines

The USPTO has granted patent US12584146B2 to City of Hope for synthetic modified vaccinia Ankara (SMVA) based vaccine compositions designed to prevent or treat coronavirus infections. The patent covers novel vaccine formulations and methods of production.